Automatic annotation results for Homo_sapiens.fasta



Ssequence id Locus Description Alignment Score E-value % Sequence Identity EC number COG Function KEGG Pathways GeneOntology
ENST00000009120 Metalloprotease mmp21/22A related cluster 1727 0.0 92% (317/342) GO:0000004|biological_process unknown|ND; GO:0004222|metalloendopeptidase activity|IEA; GO:0004222|metalloendopeptidase activity|ISS; GO:0004222|metalloendopeptidase activity|NAS; GO:0005578|extracellular matrix (sensu Metazoa)|IEA; GO:0005578|extracellular matrix (sensu Metazoa)|NAS; GO:0005622|intracellular|ISS; GO:0006508|proteolysis and peptidolysis|IEA; GO:0008233|peptidase activity|IEA; GO:0008237|metallopeptidase activity|IEA; GO:0008270|zinc ion binding|ISS
ENST00000011700 Vps13d Vps13d; vacuolar protein sorting 13D (yeast) 19676 0.0 90% (3820/4239) Intracellular trafficking, secretion, and vesicular transport
ENST00000029717 Tnfrsf1b Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b) (Etanercept) [Contains: Tumor necrosis factor binding protein 2 (TBPII) (TBP-2)] related cluster 2133 0.0 90% (397/441) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006915|apoptosis|IEA; GO:0016021|integral to membrane|IEA; GO:0019221|cytokine and chemokine mediated signaling pathway|IEA
ENST00000054661 G6PE GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)] related cluster 4156 0.0 99% (790/791) 1.1.1.47 Carbohydrate transport and metabolism GO:0003824|catalytic activity|IEA; GO:0004345|glucose-6-phosphate 1-dehydrogenase activity|IEA; GO:0004345|glucose-6-phosphate 1-dehydrogenase activity|TAS; GO:0005489|electron transporter activity|NR; GO:0005783|endoplasmic reticulum|IEA; GO:0005975|carbohydrate metabolism|IEA; GO:0006006|glucose metabolism|IEA; GO:0006098|pentose-phosphate shunt|IEA; GO:0016491|oxidoreductase activity|IEA; GO:0016787|hydrolase activity|IEA; GO:0017057|6-phosphogluconolactonase activity|IEA; GO:0047936|glucose 1-dehydrogenase activity|IEA
ENST00000054668 Uts2 Urotensin-2 precursor related cluster 529 3e-53 86% (106/122) Neuroactive ligand-receptor interaction GO:0005102|receptor binding|TAS; GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|TAS; GO:0005576|extracellular region|IEA; GO:0005615|extracellular space|TAS; GO:0006936|muscle contraction|TAS; GO:0007268|synaptic transmission|TAS; GO:0008217|regulation of blood pressure|TAS
ENST00000054670 Tnfrsf9 Tumor necrosis factor receptor superfamily member 9 precursor related cluster 1259 1e-138 91% (226/246) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0004872|receptor activity|TAS; GO:0005887|integral to plasma membrane|TAS; GO:0006917|induction of apoptosis|TAS; GO:0006955|immune response|NR; GO:0008285|negative regulation of cell proliferation|TAS; GO:0016021|integral to membrane|IEA
ENST00000062030 Akr7a5 Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) 1338 1e-148 77% (250/323)
ENST00000062038 [J] COG0244 Ribosomal protein L10 493 1e-49 50% (103/202) Translation, ribosomal structure and biogenesis
ENST00000072205 LOC230872 LOC230872; rootletin 5386 0.0 63% (1212/1919)
ENST00000160698 Trp73 Tumor protein p73 related cluster 3237 0.0 95% (608/636) GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|IEA; GO:0003700|transcription factor activity|TAS; GO:0005515|protein binding|IPI; GO:0005634|nucleus|IEA; GO:0006298|mismatch repair|TAS; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0006915|apoptosis|IEA; GO:0008630|DNA damage response, signal transduction resulting in induction of apoptosis|TAS; GO:0045786|negative regulation of cell cycle|IEA
ENST00000164247 Kcnab2 Voltage-gated potassium channel beta-2 subunit (K(+) channel beta-2 subunit) related cluster 1906 0.0 100% (367/367) GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005249|voltage-gated potassium channel activity|IEA; GO:0005737|cytoplasm|IEA; GO:0005737|cytoplasm|NR; GO:0006811|ion transport|IEA; GO:0006813|potassium ion transport|IEA; GO:0015459|potassium channel regulator activity|TAS; GO:0016021|integral to membrane|IEA
ENST00000168666 Per3 Period circadian protein 3 related cluster 5354 0.0 86% (1037/1196) GO:0004871|signal transducer activity|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007165|signal transduction|IEA; GO:0048511|rhythmic process|IEA
ENST00000196061 PLOD1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor related cluster 3804 0.0 97% (711/727) 1.14.11.4 Lysine degradation GO:0005489|electron transporter activity|NAS; GO:0005489|electron transporter activity|NR; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|NAS; GO:0008475|procollagen-lysine 5-dioxygenase activity|IEA; GO:0008544|epidermis development|TAS; GO:0016020|membrane|IEA; GO:0016491|oxidoreductase activity|IEA; GO:0016702|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|IEA; GO:0016706|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|IEA; GO:0019538|protein metabolism|IEA
ENST00000234487 Clcn6 Chloride channel protein 6 related cluster 3954 0.0 90% (766/848) Inorganic ion transport and metabolism GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS
ENST00000234490 Dnajc11 Dnajc11; DnaJ (Hsp40) homolog, subfamily C, member 11 1553 1e-172 92% (302/327) Posttranslational modification, protein turnover, chaperones
ENST00000234492 Pax7 Pax7; paired box gene 7 2263 0.0 91% (430/468)
ENST00000234646 Pqlc2 Pqlc2; PQ loop repeat containing 2 928 2e-99 86% (179/207)
ENST00000234875 Rpl22 60S ribosomal protein L22 related cluster 401 1e-37 81% (81/99) Ribosome GO:0003723|RNA binding|IEA; GO:0003723|RNA binding|TAS; GO:0003735|structural constituent of ribosome|IEA; GO:0003735|structural constituent of ribosome|TAS; GO:0005622|intracellular|IEA; GO:0005840|ribosome|IEA; GO:0005842|cytosolic large ribosomal subunit (sensu Eukaryota)|TAS; GO:0006412|protein biosynthesis|IEA; GO:0006412|protein biosynthesis|TAS; GO:0008201|heparin binding|IEA
ENST00000234897 Phf13 PHD finger protein 13 related cluster 1402 1e-154 88% (265/300) GO:0003677|DNA binding|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA
ENST00000234909 LOC313729 Mitogen-inducible gene 6 protein related cluster 2130 0.0 89% (412/462) GO:0005100|Rho GTPase activator activity|TAS; GO:0005737|cytoplasm|TAS; GO:0006950|response to stress|TAS
ENST00000234912 Chain B, Crystal Structure Of The K130r Mutant Of Human Dj-1 pdb|1PE0|A Chain A, Crystal Structure Of The K130r Mutant Of Human Dj-1 943 1e-100 99% (188/189)
ENST00000235287 SPEE Spermidine synthase related cluster 1478 1e-164 97% (281/287) 2.5.1.16 Amino acid transport and metabolism Arginine and proline metabolism Urea cycle and metabolism of amino groups beta-Alanine metabolism GO:0003824|catalytic activity|IEA; GO:0004766|spermidine synthase activity|IEA; GO:0004766|spermidine synthase activity|TAS; GO:0008295|spermidine biosynthesis|IEA; GO:0008757|S-adenosylmethionine-dependent methyltransferase activity|IEA; GO:0016740|transferase activity|IEA
ENST00000235299 Fbxo2 F-box only protein 2 related cluster 1199 1e-131 76% (225/296) GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|TAS; GO:0005515|protein binding|IEA; GO:0006464|protein modification|TAS; GO:0006508|proteolysis and peptidolysis|TAS; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA
ENST00000235310 Mad2l2 Mitotic spindle assembly checkpoint protein MAD2B related cluster 1043 1e-113 94% (200/211) 2.7.7.7 DNA polymerase GO:0007049|cell cycle|IEA; GO:0007067|mitosis|IEA; GO:0007067|mitosis|NAS; GO:0007094|mitotic spindle checkpoint|TAS
ENST00000235329 Mfn2 Transmembrane GTPase MFN2 related cluster 3704 0.0 96% (729/758) General function prediction only GO:0003924|GTPase activity|IEA; GO:0005525|GTP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0016021|integral to membrane|IEA; GO:0016787|hydrolase activity|IEA; GO:0019867|outer membrane|IEA
ENST00000235332 IGFBP-2-Binding Protein, IIp45 related cluster 1727 0.0 90% (321/353)
ENST00000235372 LOC313678 LOC313678; similar to zinc finger protein RIZ 2423 0.0 74% (473/631) General function prediction only
ENST00000235417 LOC298607 LOC298607; similar to Agmatinase, mitochondrial precursor (Agmatine ureohydrolase) (AUH) 1437 1e-159 83% (274/328) Amino acid transport and metabolism
ENST00000235432 Plekhm2 Plekhm2; pleckstrin homology domain containing, family M (with RUN domain) member 2 4260 0.0 81% (828/1019)
ENST00000235455 Zbtb17 Zbtb17; zinc finger and BTB domain containing 17 3480 0.0 83% (661/788) General function prediction only
ENST00000235768 Sdhb Sdhb; succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [EC:1.3.5.1] [KO:K00235] 1347 1e-149 89% (250/278) 1.3.5.1 Energy production and conversion Citrate cycle (TCA cycle) Oxidative phosphorylation
ENST00000235772 Mfap2 Mfap2; microfibrillar-associated protein 2 660 2e-68 81% (122/150)
ENST00000235799 actin 565 4e-57 35% (127/357) Cytoskeleton
ENST00000235835 Akr7a5 Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) 1569 1e-175 86% (297/343)
ENST00000235865 Pla2g5 Pla2g5; phospholipase A2, group V [EC:3.1.1.4] [KO:K01047] 512 3e-51 68% (94/137) 3.1.1.4 Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism
ENST00000235867 Pla2g2d Pla2g2d; phospholipase A2, group IID [EC:3.1.1.4] [KO:K01047] 625 5e-64 71% (103/145) 3.1.1.4 Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism
ENST00000235894 Ddost Ddost; dolichyl-di-phosphooligosaccharide-protein glycotransferase [EC:2.4.1.119] [KO:K00730] 2037 0.0 94% (392/417) 2.4.1.119 N-Glycan biosynthesis
ENST00000240174 Nppb Natriuretic peptides B precursor [Contains: Gamma-brain natriuretic peptide; Brain natriuretic peptide 32 (BNP-32)] related cluster 619 1e-63 90% (121/134) GO:0005102|receptor binding|IPI; GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|NAS; GO:0005576|extracellular region|IEA; GO:0005576|extracellular region|TAS; GO:0005615|extracellular space|NAS; GO:0007166|cell surface receptor linked signal transduction|NAS; GO:0007589|fluid secretion|TAS; GO:0008217|regulation of blood pressure|NAS; GO:0008613|diuretic hormone activity|TAS; GO:0016525|negative regulation of angiogenesis|TAS; GO:0030146|diuresis|TAS; GO:0030147|natriuresis|TAS; GO:0030308|negative regulation of cell growth|NAS; GO:0042312|regulation of vasodilation|NAS; GO:0043114|regulation of vascular permeability|TAS
ENST00000240179 LOC313706 Transitional epithelia response protein related cluster 1616 1e-180 94% (319/338) GO:0016020|membrane|IEA
ENST00000240185 Tardbp TAR DNA-binding protein-43 related cluster 1543 1e-171 74% (308/414) General function prediction only GO:0000398|nuclear mRNA splicing, via spliceosome|IEA; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|TAS; GO:0003723|RNA binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0006366|transcription from Pol II promoter|TAS; GO:0006397|mRNA processing|IEA; GO:0007067|mitosis|TAS; GO:0008017|microtubule binding|TAS
ENST00000241542 Mint Mint; Msx2 interacting nuclear target protein 11585 0.0 67% (2423/3596)
ENST00000244841 Pin Pin; dynein, cytoplasmic, light chain 1 419 4e-41 87% (78/89)
ENST00000245530 Padi2 Padi2; peptidyl arginine deiminase, type II [EC:3.5.3.15] 3321 0.0 93% (623/665) 3.5.3.15
ENST00000246421 Unassigned protein
ENST00000246422 [G] COG0061 Predicted sugar kinase 495 3e-49 39% (104/261) Carbohydrate transport and metabolism
ENST00000247986 Kif17 Kif17; kinesin family member 17 3962 0.0 78% (806/1028) Cytoskeleton
ENST00000248008 LOC313658 LOC313658; similar to retinoblastoma-associated factor 600 23413 0.0 89% (4598/5155)
ENST00000248017 LOC298581 LOC298581; similar to group IIE secreted phospholipase A2 674 1e-70 90% (112/124)
ENST00000251544 Fbxo6b F-box only protein 6 related cluster 1531 1e-170 95% (281/293) GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA
ENST00000251546 Fbxo44 F-box only protein 44 related cluster 492 1e-112 100% (87/87) GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA
ENST00000251547 Fbxo44 F-box only protein 44 related cluster 1313 1e-144 94% (237/250) GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA
ENST00000253251 Ube4b Ubiquitin conjugation factor E4 B related cluster 5281 0.0 87% (1030/1173) Posttranslational modification, protein turnover, chaperones GO:0000151|ubiquitin ligase complex|IEA; GO:0000151|ubiquitin ligase complex|TAS; GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0004842|ubiquitin-protein ligase activity|TAS; GO:0005515|protein binding|IPI; GO:0005737|cytoplasm|IDA; GO:0006457|protein folding|NAS; GO:0006511|ubiquitin-dependent protein catabolism|TAS; GO:0006512|ubiquitin cycle|IEA; GO:0006915|apoptosis|ISS; GO:0008151||NAS; GO:0009411|response to UV|ISS; GO:0016567|protein ubiquitination|IEA; GO:0019899|enzyme binding|IPI; GO:0042787|protein ubiquitination during ubiquitin-dependent protein catabolism|TAS; GO:0051082|unfolded protein binding|NAS
ENST00000253887 Mrpl20 Mitochondrial ribosomal protein L20 related cluster 771 1e-81 100% (149/149) Translation, ribosomal structure and biogenesis GO:0003723|RNA binding|IEA; GO:0003735|structural constituent of ribosome|IEA; GO:0005622|intracellular|IEA; GO:0005840|ribosome|IEA; GO:0006412|protein biosynthesis|IEA; GO:0019843|rRNA binding|IEA; GO:0030529|ribonucleoprotein complex|IEA
ENST00000253987 CAH6 Carbonic anhydrase VI precursor related cluster 1593 1e-177 95% (295/308) 4.2.1.1 Inorganic ion transport and metabolism Nitrogen metabolism GO:0004089|carbonate dehydratase activity|IEA; GO:0004089|carbonate dehydratase activity|TAS; GO:0006730|one-carbon compound metabolism|IEA; GO:0008270|zinc ion binding|IEA; GO:0016829|lyase activity|IEA
ENST00000253998 Nephrocystin 4 related cluster 321 6e-28 100% (59/59) GO:0005198|structural molecule activity|NAS; GO:0005515|protein binding|IPI; GO:0007165|signal transduction|NAS; GO:0007632|visual behavior|NAS; GO:0016020|membrane|IC; GO:0016337|cell-cell adhesion|NAS; GO:0030036|actin cytoskeleton organization and biogenesis|NAS
ENST00000255573 LOC298578 LOC298578; similar to Group IIF secretory phospholipase A2 precursor (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF) 853 1e-90 66% (156/236)
ENST00000262450 Chd5 Chromodomain helicase-DNA-binding protein 5 related cluster 8272 0.0 82% (1606/1950) GO:0000151|ubiquitin ligase complex|IEA; GO:0000785|chromatin|IEA; GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA; GO:0003682|chromatin binding|IEA; GO:0004386|helicase activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0006333|chromatin assembly or disassembly|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008026|ATP-dependent helicase activity|IEA; GO:0008270|zinc ion binding|IEA; GO:0016567|protein ubiquitination|IEA; GO:0016568|chromatin modification|IEA
ENST00000263495 Putative MAPK activating protein related cluster 609 4e-62 92% (122/132)
ENST00000263741 45 kDa calcium-binding protein precursor related cluster 307 1e-26 98% (58/59) GO:0005509|calcium ion binding|IEA; GO:0005794|Golgi apparatus|IEA
ENST00000263743 Dvl1 Segment polarity protein dishevelled homolog DVL-1 related cluster 175 1e-149 100% (35/35) Wnt signaling pathway GO:0003677|DNA binding|IEA; GO:0004871|signal transducer activity|IEA; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005737|cytoplasm|TAS; GO:0007165|signal transduction|TAS; GO:0007222|frizzled signaling pathway|IEA; GO:0007242|intracellular signaling cascade|IEA; GO:0007275|development|IEA; GO:0007507|heart development|TAS; GO:0009653|morphogenesis|TAS; GO:0016055|Wnt receptor signaling pathway|IEA
ENST00000263746 Atad3a AAA-ATPase TOB3 related cluster 2440 0.0 76% (501/654) General function prediction only GO:0000166|nucleotide binding|IEA; GO:0005524|ATP binding|IEA; GO:0017111|nucleoside-triphosphatase activity|IEA
ENST00000263750 Gnb1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 related cluster 177 4e-11 25% (53/210) GO:0004871|signal transducer activity|IEA; GO:0007165|signal transduction|IEA
ENST00000263932 Tnfrsf8 Tumor necrosis factor receptor superfamily member 8 precursor related cluster 2845 0.0 89% (531/593) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0004888|transmembrane receptor activity|TAS; GO:0007165|signal transduction|TAS; GO:0008285|negative regulation of cell proliferation|TAS; GO:0016021|integral to membrane|IEA
ENST00000263934 Kif1b Kinesin-like protein KIF1B related cluster 8121 0.0 90% (1610/1770) Cytoskeleton GO:0003774|motor activity|IEA; GO:0003777|microtubule motor activity|ISS; GO:0005515|protein binding|ISS; GO:0005524|ATP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0005875|microtubule associated complex|IEA; GO:0005875|microtubule associated complex|ISS; GO:0007018|microtubule-based movement|ISS; GO:0007270|nerve-nerve synaptic transmission|ISS; GO:0007274|neuromuscular synaptic transmission|ISS; GO:0008017|microtubule binding|ISS; GO:0008089|anterograde axon cargo transport|ISS; GO:0009790|embryonic development|ISS; GO:0016887|ATPase activity|ISS; GO:0019894|kinesin binding|TAS; GO:0030659|cytoplasmic vesicle membrane|ISS; GO:0030705|cytoskeleton-dependent intracellular transport|ISS
ENST00000264203 Capzb Capzb; F-actin capping protein beta subunit 1415 1e-156 100% (271/271)
ENST00000264205 ECE1 Endothelin-converting enzyme 1 related cluster 3997 0.0 97% (750/770) 3.4.24.71 GO:0004222|metalloendopeptidase activity|TAS; GO:0004245|neprilysin activity|IEA; GO:0005624|membrane fraction|TAS; GO:0006508|proteolysis and peptidolysis|IEA; GO:0007267|cell-cell signaling|NR; GO:0008237|metallopeptidase activity|IEA; GO:0008270|zinc ion binding|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|TAS; GO:0016512|endothelin-converting enzyme 1 activity|IEA; GO:0016787|hydrolase activity|IEA
ENST00000264206 Usp48 Ubiquitin-specific protease 31 related cluster 5402 0.0 98% (1016/1035) Posttranslational modification, protein turnover, chaperones GO:0004197|cysteine-type endopeptidase activity|IEA; GO:0004221|ubiquitin thiolesterase activity|IEA; GO:0006511|ubiquitin-dependent protein catabolism|IEA; GO:0008233|peptidase activity|IEA
ENST00000270684 Slc2a5 Solute carrier family 2, facilitated glucose transporter, member 5 related cluster 2185 0.0 88% (441/501) GO:0005215|transporter activity|IEA; GO:0005351|sugar porter activity|IEA; GO:0005353|fructose transporter activity|IEA; GO:0005353|fructose transporter activity|TAS; GO:0005355|glucose transporter activity|IEA; GO:0005355|glucose transporter activity|TAS; GO:0005886|plasma membrane|TAS; GO:0005975|carbohydrate metabolism|TAS; GO:0006810|transport|IEA; GO:0008643|carbohydrate transport|IEA; GO:0015755|fructose transport|TAS; GO:0015758|glucose transport|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000270685 LOC435818 Intestinal facilitative glucose transporter 7 related cluster 2479 0.0 93% (491/524) GO:0005215|transporter activity|IEA; GO:0005351|sugar porter activity|IEA; GO:0005355|glucose transporter activity|IEA; GO:0006810|transport|IEA; GO:0008643|carbohydrate transport|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000270691 Espn Espn; espin 854 6e-91 63% (196/308)
ENST00000270708 Wdr8 WD-repeat protein 8 related cluster 2483 0.0 100% (460/460) General function prediction only
ENST00000270722 PR-domain zinc finger protein 16 related cluster 6181 0.0 91% (1170/1275) General function prediction only GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IC; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|NAS; GO:0005634|nucleus|IC; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IC; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008270|zinc ion binding|IEA
ENST00000270728 Ela2 Ela2; elastase 2 [EC:3.4.21.71] 1220 1e-134 83% (224/269) 3.4.21.71 Posttranslational modification, protein turnover, chaperones
ENST00000270733 Padi3 Padi3; peptidyl arginine deiminase, type III [EC:3.5.3.15] 3151 0.0 87% (581/663) 3.5.3.15
ENST00000270737 Padi1 Padi1; peptidyl arginine deiminase, type I [EC:3.5.3.15] 2673 0.0 75% (501/662) 3.5.3.15
ENST00000270747 Arhgef19 Arhgef19; Rho guanine nucleotide exchange factor (GEF) 19 3151 0.0 79% (634/801) Signal transduction mechanisms
ENST00000270750 LOC298609 LOC298609; similar to Swiprosin 1 799 2e-84 71% (171/238)
ENST00000270774 Pex14 Peroxisomal membrane protein PEX14 related cluster 1355 1e-149 76% (276/362) GO:0005777|peroxisome|IEA; GO:0005777|peroxisome|TAS; GO:0005779|integral to peroxisomal membrane|TAS; GO:0016020|membrane|IEA
ENST00000270776 6PGD 6-phosphogluconate dehydrogenase, decarboxylating related cluster 2431 0.0 97% (464/475) 1.1.1.44 Carbohydrate transport and metabolism Pentose phosphate pathway GO:0004616|phosphogluconate dehydrogenase (decarboxylating) activity|IEA; GO:0005489|electron transporter activity|TAS; GO:0006098|pentose-phosphate shunt|IEA; GO:0009051|pentose-phosphate shunt, oxidative branch|TAS; GO:0016491|oxidoreductase activity|IEA
ENST00000288032 Epha2 Epha2; Eph receptor A2 [EC:2.7.1.112] [KO:K05103] 4593 0.0 91% (869/952) 2.7.1.112
ENST00000288660 LOC302697 LOC302697; similar to Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (eIF-4C) 510 2e-51 98% (97/98) Translation, ribosomal structure and biogenesis
ENST00000288709 PREDICTED: similar to membrane metallo-endopeptidase-like 2 [Canis familiaris] 3280 0.0 86% (612/710) Posttranslational modification, protein turnover, chaperones
ENST00000288726 Tnfrsf14 Tumor necrosis factor receptor superfamily member 14 precursor related cluster 1578 1e-175 100% (283/283) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0004888|transmembrane receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005887|integral to plasma membrane|IC; GO:0006915|apoptosis|IEA; GO:0006955|immune response|IEA; GO:0006955|immune response|TAS; GO:0007165|signal transduction|IEA; GO:0007166|cell surface receptor linked signal transduction|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000288738 PANK4 Pantothenate kinase 4 related cluster 3749 0.0 94% (729/771) 2.7.1.33 Coenzyme transport and metabolism GO:0004594|pantothenate kinase activity|IEA; GO:0005524|ATP binding|IEA; GO:0015937|coenzyme A biosynthesis|IEA; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA
ENST00000288774 Peroxisome assembly protein 10 related cluster 1224 1e-134 72% (244/337) GO:0000151|ubiquitin ligase complex|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005777|peroxisome|IEA; GO:0005778|peroxisomal membrane|NAS; GO:0007031|peroxisome organization and biogenesis|IDA; GO:0008270|zinc ion binding|IEA; GO:0008270|zinc ion binding|NAS; GO:0016020|membrane|IEA; GO:0016558|peroxisome matrix protein import|IDA; GO:0016567|protein ubiquitination|IEA
ENST00000288796 Ski Ski oncogene related cluster 2738 0.0 76% (546/711) GO:0005554|molecular_function unknown|ND; GO:0005634|nucleus|IEA; GO:0005634|nucleus|NAS; GO:0008151||IEA; GO:0030154|cell differentiation|NAS
ENST00000288816 KPCZ Protein kinase C, zeta type related cluster 3151 0.0 99% (589/590) 2.7.1.37 Calcium signaling pathway MAPK signaling pathway Phosphatidylinositol signaling system Wnt signaling pathway GO:0004672|protein kinase activity|IEA; GO:0004672|protein kinase activity|TAS; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0004700|atypical protein kinase C activity|TAS; GO:0005524|ATP binding|IEA; GO:0005624|membrane fraction|TAS; GO:0005737|cytoplasm|TAS; GO:0005886|plasma membrane|TAS; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006468|protein amino acid phosphorylation|TAS; GO:0006916|anti-apoptosis|TAS; GO:0007165|signal transduction|TAS; GO:0007242|intracellular signaling cascade|IEA; GO:0016740|transferase activity|IEA; GO:0019992|diacylglycerol binding|IEA
ENST00000289226 Gpr153 G protein-coupled receptor 153 related cluster 2479 0.0 80% (493/609) GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004872|receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0016021|integral to membrane|IEA
ENST00000289749 Nbl1 Nbl1; neuroblastoma, suppression of tumorigenicity 1 677 3e-70 80% (128/160)
ENST00000289753 Htr6 Htr6; 5-hydroxytryptamine (serotonin) receptor 6 [KO:K04162] 1576 1e-175 73% (322/440) Calcium signaling pathway Neuroactive ligand-receptor interaction
ENST00000289839 LOC362638 LOC362638; similar to CYTIDINE DEAMINASE (CYTIDINE AMINOHYDROLASE) 663 5e-69 82% (119/144) Nucleotide transport and metabolism
ENST00000289840 LOC298575 LOC298575; similar to protein kinase BRPK [KO:K05688] 2307 0.0 80% (450/560) Neurodegenerative Disorders Parkinson's disease
ENST00000289877 Proton-associated sugar transporter A related cluster 2291 0.0 89% (448/498) GO:0005351|sugar porter activity|IEA; GO:0006810|transport|IEA; GO:0015293|symporter activity|IEA; GO:0016021|integral to membrane|IEA
ENST00000290507 Padi4 Padi4; peptidyl arginine deiminase, type IV [EC:3.5.3.15] 2553 0.0 72% (480/663) 3.5.3.15
ENST00000290597 Aldh4a1 Aldh4a1; aldehyde dehydrogenase 4 family, member A1 2720 0.0 92% (505/547) Energy production and conversion
ENST00000291355 Dffa DNA fragmentation factor alpha subunit related cluster 1586 1e-176 95% (317/331) Apoptosis GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS
ENST00000294399 LOC362668 Krueppel-related zinc finger protein 3 related cluster 3557 0.0 96% (663/688) General function prediction only GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|TAS; GO:0005515|protein binding|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008270|zinc ion binding|IEA
ENST00000294427 LOC362653 [O] COG5640 Secreted trypsin-like serine protease 241 3e-20 30% (73/240) Posttranslational modification, protein turnover, chaperones
ENST00000294431 Lzic Leucine zipper & ICAT homologous protein LZIC related cluster 709 5e-74 81% (154/190) GO:0007275|development|IEA; GO:0008013|beta-catenin binding|IEA
ENST00000294435 Rbp7 Retinol-binding protein IV, cellular related cluster 726 3e-76 100% (134/134) GO:0005215|transporter activity|IEA; GO:0005488|binding|IEA; GO:0006810|transport|IEA; GO:0008289|lipid binding|IEA; GO:0019841|retinol binding|IEA
ENST00000294450 Cal Cal; CSX-associated LIM 1280 1e-141 66% (248/373)
ENST00000294489 Gp38 Gp38; glycoprotein 38 211 2e-15 36% (59/162)
ENST00000294492 Dhrs3 Dhrs3; dehydrogenase/reductase (SDR family) member 3 1488 1e-165 95% (287/302)
ENST00000294544 Ubxd3 Ubxd3; UBX domain containing 3 906 1e-96 65% (183/280)
ENST00000294546 LOC287005 LOC287005; CaM-kinase II inhibitor alpha 333 3e-30 82% (64/78)
ENST00000294599 Egfl3 Multiple EGF-like-domain protein 3 related cluster 7106 0.0 96% (1188/1237) GO:0000004|biological_process unknown|ND; GO:0005198|structural molecule activity|IEA; GO:0005509|calcium ion binding|IEA; GO:0005509|calcium ion binding|NAS; GO:0008372|cellular_component unknown|ND
ENST00000302666 PK3CD Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform related cluster 4960 0.0 90% (949/1044) 2.7.1.153 Apoptosis Inositol phosphate metabolism Jak-STAT signaling pathway Phosphatidylinositol signaling system Regulation of actin cytoskeleton Toll-like receptor signaling pathway GO:0004428|inositol or phosphatidylinositol kinase activity|IEA; GO:0005942|phosphoinositide 3-kinase complex|IEA; GO:0005942|phosphoinositide 3-kinase complex|NAS; GO:0006468|protein amino acid phosphorylation|NAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|NAS; GO:0016301|kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|NAS; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|IEA
ENST00000302692 Mitochondrial carrier protein MGC4399 related cluster 1613 1e-180 100% (316/316) GO:0005488|binding|IEA; GO:0005743|mitochondrial inner membrane|IEA; GO:0006810|transport|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000303152 Dffb DNA fragmentation factor 40 kDa subunit related cluster 1789 0.0 100% (338/338) 3.-.-.- Apoptosis GO:0004518|nuclease activity|IEA; GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS; GO:0016787|hydrolase activity|IEA
ENST00000304185 PUSL1 Pseudouridylate synthase-like 1 related cluster 1460 1e-162 95% (282/294) 4.2.1.70 Translation, ribosomal structure and biogenesis GO:0004730|pseudouridylate synthase activity|IEA; GO:0008033|tRNA processing|IEA; GO:0016829|lyase activity|IEA
ENST00000304436 Angpt1 Angiopoietin-4 precursor related cluster 512 1e-50 36% (108/297) GO:0000004|biological_process unknown|ND; GO:0005554|molecular_function unknown|ND; GO:0030297|transmembrane receptor protein tyrosine kinase activator activity|NAS
ENST00000304457 Polymyositis/scleroderma autoantigen 2 related cluster 4203 0.0 95% (819/860) GO:0003676|nucleic acid binding|IEA; GO:0003723|RNA binding|IEA; GO:0004518|nuclease activity|IEA; GO:0004527|exonuclease activity|IEA; GO:0004674|protein serine/threonine kinase activity|TAS; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005730|nucleolus|TAS; GO:0006364|rRNA processing|IEA; GO:0008408|3'-5' exonuclease activity|IEA; GO:0016787|hydrolase activity|IEA
ENST00000304706 Arpm2 Actin related protein M2 related cluster 1972 0.0 100% (377/377) Cytoskeleton GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|IEA; GO:0015629|actin cytoskeleton|IEA
ENST00000306256 LOC298675 LOC298675; similar to RER1 homolog 1029 1e-111 96% (189/196)
ENST00000307786 Calglandulin-like protein related cluster 820 5e-87 100% (164/164) GO:0005509|calcium ion binding|IEA
ENST00000308271 Usp48 Ubiquitin-specific protease 31 related cluster 5065 0.0 98% (963/982) Posttranslational modification, protein turnover, chaperones GO:0004197|cysteine-type endopeptidase activity|IEA; GO:0004221|ubiquitin thiolesterase activity|IEA; GO:0006511|ubiquitin-dependent protein catabolism|IEA; GO:0008233|peptidase activity|IEA
ENST00000308647 Atad3a AAA-ATPase TOB3 related cluster 2662 0.0 93% (522/556) GO:0000166|nucleotide binding|IEA; GO:0005524|ATP binding|IEA; GO:0017111|nucleoside-triphosphatase activity|IEA
ENST00000309212 Limitrin related cluster 1809 0.0 79% (351/442)
ENST00000311890 Hspb7 Hspb7; heat shock protein family, member 7 (cardiovascular) 660 4e-68 92% (129/140)
ENST00000312301 Nppa Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide) (ANP) (Prepronatriodilatin) [Contains: Cardiodilatin-related peptide (CDP)] related cluster 623 4e-64 89% (119/133) GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|NAS; GO:0005576|extracellular region|IEA; GO:0005576|extracellular region|NAS; GO:0007582|physiological process|IEA; GO:0008217|regulation of blood pressure|IDA
ENST00000312413 Clcn6 Chloride channel protein 6 related cluster 1365 1e-150 89% (266/297) Inorganic ion transport and metabolism GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS
ENST00000314340 Agtrap AGTRAP protein related cluster 823 2e-87 100% (158/158)
ENST00000315234 ICMT Protein-S-isoprenylcysteine O-methyltransferase related cluster 1303 1e-143 90% (246/273) 2.1.1.100 Posttranslational modification, protein turnover, chaperones GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA
ENST00000315901 Rbp7 Retinol-binding protein IV, cellular related cluster 126 9e-06 100% (24/24) GO:0005215|transporter activity|IEA; GO:0005488|binding|IEA; GO:0006810|transport|IEA; GO:0008289|lipid binding|IEA; GO:0019841|retinol binding|IEA
ENST00000317137 LOC298675 LOC298675; similar to RER1 homolog 383 1e-107 93% (69/74)
ENST00000317673 CD2L1 PITSLRE serine/threonine-protein kinase CDC2L1 related cluster 574 3e-58 71% (120/167) 2.7.1.37 GO:0000074|regulation of cell cycle|IEP; GO:0001558|regulation of cell growth|IEP; GO:0004672|protein kinase activity|IEA; GO:0004674|protein serine/threonine kinase activity|IDA; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0005524|ATP binding|IDA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|IEP; GO:0006468|protein amino acid phosphorylation|IDA; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006915|apoptosis|IEA; GO:0007049|cell cycle|IEA; GO:0007067|mitosis|NAS; GO:0016740|transferase activity|IEA; GO:0050684|regulation of mRNA processing|IDA
ENST00000317967 LOC313644 Rap1 GTPase-activating protein 1 related cluster 3149 0.0 91% (607/664) GO:0005096|GTPase activator activity|IEA; GO:0005096|GTPase activator activity|TAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0016020|membrane|IEA
ENST00000319254 G protein-coupled receptor 157 related cluster 594 5e-61 73% (114/155) GO:0004872|receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0016020|membrane|IEA
ENST00000320153 ddi2 ddi2; DNA-damage inducible protein 2 1505 1e-167 77% (305/394)
ENST00000320485 Cort CORT related cluster 700 6e-73 86% (133/154) Neuroactive ligand-receptor interaction GO:0005179|hormone activity|IEA; GO:0005576|extracellular region|IEA
ENST00000320498 Cort Cortistatin, isoform d related cluster 420 5e-40 100% (83/83) Neuroactive ligand-receptor interaction GO:0003677|DNA binding|IEA
ENST00000321729 MGC94202 Aurora-A kinase interacting protein related cluster 1054 1e-114 100% (199/199) GO:0005515|protein binding|IPI; GO:0005634|nucleus|IDA; GO:0005634|nucleus|IEA; GO:0045839|negative regulation of mitosis|NAS
ENST00000322762 LOC298683 Von Willebrand factor A domain-related protein, isoform 1 related cluster 1817 0.0 82% (365/445)
ENST00000323338 MTHR Methylenetetrahydrofolate reductase related cluster 3259 0.0 93% (612/656) 1.5.1.20 Amino acid transport and metabolism One carbon pool by folate GO:0003824|catalytic activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|TAS; GO:0006520|amino acid metabolism|TAS; GO:0006555|methionine metabolism|IEA; GO:0008015|circulation|TAS; GO:0016491|oxidoreductase activity|IEA
ENST00000323910 Thap1 THAP domain protein 3 related cluster 770 7e-81 95% (146/153) GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA
ENST00000325267 Tas1r2 Tas1r2; taste receptor, type 1, member 2 [KO:K04625] 2954 0.0 64% (543/838)
ENST00000325764 Catnbip1 Beta-catenin-interacting protein 1 related cluster 405 7e-38 100% (81/81) Wnt signaling pathway GO:0005515|protein binding|TAS; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|TAS; GO:0007165|signal transduction|TAS; GO:0007275|development|IEA; GO:0007275|development|TAS; GO:0008013|beta-catenin binding|IEA; GO:0008283|cell proliferation|TAS; GO:0016055|Wnt receptor signaling pathway|IEA
ENST00000326183 Olfr1289 Olfactory receptor 4F4 related cluster 1480 1e-164 94% (287/305) GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA
ENST00000326216 B3galt6 B3galt6; UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6 [EC:2.4.1.134] [KO:K00734] 1070 1e-116 77% (202/262) 2.4.1.134 Chondroitin / Heparan sulfate biosynthesis
ENST00000327169 Olr777 Olfactory receptor 4F3 related cluster 1540 1e-171 95% (297/312) GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA
ENST00000328565 Tnfrsf4 Tumor necrosis factor receptor superfamily member 4 precursor related cluster 1248 1e-137 87% (223/254) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005887|integral to plasma membrane|TAS; GO:0006955|immune response|TAS; GO:0016021|integral to membrane|IEA
ENST00000328596 Tnfrsf18 Tumor necrosis factor receptor superfamily member 18 precursor related cluster 119 6e-05 61% (24/39) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006916|anti-apoptosis|TAS; GO:0007165|signal transduction|TAS; GO:0016021|integral to membrane|IEA
ENST00000330361 Pla2g2a Pla2g2a; phospholipase A2, group IIA (platelets, synovial fluid) [EC:3.1.1.4] [KO:K01047] 506 2e-50 65% (95/144) 3.1.1.4 Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism
ENST00000331433 Clcnk1 Clcnk1; chloride channel K1 [KO:K05017] 2709 0.0 76% (521/680) Inorganic ion transport and metabolism
ENST00000332831 Olr777 Olfactory receptor 4F3 related cluster 1540 1e-171 95% (297/312) GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA
ENST00000333868 Casp9 Casp9; caspase 9 [EC:3.4.22.-] [KO:K04399] 1574 1e-175 76% (318/416) 3.4.22.- Apoptosis MAPK signaling pathway
ENST00000334429 Mst1 Mst1; Macrophage stimulating 1 (hepatocyte growth factor-like) 2488 0.0 74% (462/620)
ENST00000334998 Mst1 Mst1; macrophage stimulating 1 (hepatocyte growth factor-like) 1242 1e-136 77% (222/286)
ENST00000335808 BACH Cytosolic acyl coenzyme A thioester hydrolase related cluster 1665 0.0 97% (327/336) 3.1.2.2 Lipid transport and metabolism GO:0000062|acyl-CoA binding|TAS; GO:0003824|catalytic activity|IEA; GO:0003824|catalytic activity|TAS; GO:0004759|serine esterase activity|IEA; GO:0005737|cytoplasm|TAS; GO:0006629|lipid metabolism|TAS; GO:0016290|palmitoyl-CoA hydrolase activity|IEA; GO:0016787|hydrolase activity|IEA
ENST00000336114 Cort CORT related cluster 387 4e-36 98% (71/72) Neuroactive ligand-receptor interaction GO:0005179|hormone activity|IEA; GO:0005576|extracellular region|IEA
ENST00000337061 CD2L1 PITSLRE serine/threonine-protein kinase CDC2L1 related cluster 2770 0.0 72% (567/783) 2.7.1.37 GO:0000074|regulation of cell cycle|IEP; GO:0001558|regulation of cell growth|IEP; GO:0004672|protein kinase activity|IEA; GO:0004674|protein serine/threonine kinase activity|IDA; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0005524|ATP binding|IDA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|IEP; GO:0006468|protein amino acid phosphorylation|IDA; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006915|apoptosis|IEA; GO:0007049|cell cycle|IEA; GO:0007067|mitosis|NAS; GO:0016740|transferase activity|IEA; GO:0050684|regulation of mRNA processing|IDA
ENST00000337265 Nbl1 Nbl1; neuroblastoma, suppression of tumorigenicity 1 677 3e-70 80% (128/160)
ENST00000337639 Aldh4a1 Aldh4a1; aldehyde dehydrogenase 4 family, member A1 2720 0.0 92% (505/547) Energy production and conversion
ENST00000337907 Rere RERE related cluster 4980 0.0 65% (1006/1535) Dentatorubropallidoluysian atrophy (DRPLA) GO:0000004|biological_process unknown|ND; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|IEA; GO:0005515|protein binding|NAS; GO:0005634|nucleus|IEA; GO:0005634|nucleus|NAS; GO:0006355|regulation of transcription, DNA-dependent|IEA
ENST00000338555 Scnn1a Amiloride-sensitive sodium channel delta-subunit related cluster 3144 0.0 92% (588/638) GO:0005216|ion channel activity|IEA; GO:0005272|sodium channel activity|IEA; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|NR; GO:0006811|ion transport|IEA; GO:0006814|sodium ion transport|IEA; GO:0006814|sodium ion transport|TAS; GO:0015280|amiloride-sensitive sodium channel activity|IEA; GO:0015280|amiloride-sensitive sodium channel activity|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000338591 Kelch-like protein 17 related cluster 3033 0.0 94% (592/626) GO:0003779|actin binding|IEA; GO:0005515|protein binding|IEA
ENST00000338639 Chain B, Crystal Structure Of The K130r Mutant Of Human Dj-1 pdb|1PE0|A Chain A, Crystal Structure Of The K130r Mutant Of Human Dj-1 943 1e-100 99% (188/189)
ENST00000339380 LOC298683 Von Willebrand factor A domain-related protein, isoform 1 related cluster 1105 1e-120 78% (226/289)
ENST00000340401 Arhgef16 Neuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster 2004 0.0 93% (393/421) Signal transduction mechanisms
ENST00000340468 Ubiquitin cross-reactive protein precursor related cluster 733 4e-77 93% (144/154) Posttranslational modification, protein turnover, chaperones GO:0005515|protein binding|NAS; GO:0005615|extracellular space|NAS; GO:0005737|cytoplasm|NAS; GO:0006955|immune response|IEA; GO:0007267|cell-cell signaling|NAS
ENST00000342010 NMNA1 Nicotinamide mononucleotide adenylyltransferase 1 related cluster 1458 1e-161 100% (279/279) 2.7.7.1 Coenzyme transport and metabolism GO:0000287|magnesium ion binding|IEA; GO:0000309|nicotinamide-nucleotide adenylyltransferase activity|IDA; GO:0000309|nicotinamide-nucleotide adenylyltransferase activity|IEA; GO:0005515|protein binding|IPI; GO:0005634|nucleus|IDA; GO:0005634|nucleus|IEA; GO:0006736|NADH biosynthesis|IDA; GO:0009058|biosynthesis|IEA; GO:0009435|NAD biosynthesis|IEA; GO:0016740|transferase activity|IEA; GO:0016779|nucleotidyltransferase activity|IEA; GO:0019363|pyridine nucleotide biosynthesis|IEA
ENST00000342066 Samd11 Sterile alpha motif domain containing 11 related cluster 2055 0.0 82% (411/496)
ENST00000343008 Hes1 Transcription factor HES-4 related cluster 656 6e-68 88% (134/151) GO:0003677|DNA binding|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007275|development|IEA; GO:0007399|neurogenesis|IEA
ENST00000343090 Ube4b Ubiquitin conjugation factor E4 B related cluster 5714 0.0 86% (1125/1301) Posttranslational modification, protein turnover, chaperones GO:0000151|ubiquitin ligase complex|IEA; GO:0000151|ubiquitin ligase complex|TAS; GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005737|cytoplasm|ISS; GO:0006457|protein folding|ISS; GO:0006512|ubiquitin cycle|IEA; GO:0006915|apoptosis|IDA; GO:0008151||ISS; GO:0009411|response to UV|IDA; GO:0016567|protein ubiquitination|IEA; GO:0019899|enzyme binding|ISS; GO:0042787|protein ubiquitination during ubiquitin-dependent protein catabolism|TAS; GO:0051082|unfolded protein binding|ISS
ENST00000343579 Espn Espin related cluster 780 9e-82 50% (196/386) GO:0005903|brush border|TAS; GO:0005929|cilium|IDA; GO:0015629|actin cytoskeleton|IDA; GO:0030046|parallel actin filament bundle formation|IDA; GO:0051017|actin filament bundle formation|IDA
ENST00000343813 ICMT Protein-S-isoprenylcysteine O-methyltransferase related cluster 286 1e-137 67% (57/84) 2.1.1.100 Posttranslational modification, protein turnover, chaperones GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA
ENST00000344115 Gabrd Gamma-aminobutyric-acid receptor delta subunit precursor (GABA(A) receptor) related cluster 2106 0.0 94% (409/433) Neuroactive ligand-receptor interaction GO:0004890|GABA-A receptor activity|IEA; GO:0004890|GABA-A receptor activity|TAS; GO:0005216|ion channel activity|IEA; GO:0005230|extracellular ligand-gated ion channel activity|IEA; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|IEA; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0007165|signal transduction|TAS; GO:0007268|synaptic transmission|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0030594|neurotransmitter receptor activity|IEA; GO:0045211|postsynaptic membrane|IEA
ENST00000344365 UPF0120 protein DKFZp564C186 related cluster 3405 0.0 90% (668/736) GO:0005554|molecular_function unknown|IEA; GO:0005634|nucleus|IEA
ENST00000344573 PPBT Alkaline phosphatase, tissue-nonspecific isozyme precursor related cluster 2631 0.0 99% (496/497) 3.1.3.1 Inorganic ion transport and metabolism Folate biosynthesis Glycerolipid metabolism gamma-Hexachlorocyclohexane degradation GO:0000287|magnesium ion binding|IEA; GO:0001501|skeletal development|TAS; GO:0001503|ossification|IEA; GO:0004035|alkaline phosphatase activity|IEA; GO:0008152|metabolism|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016787|hydrolase activity|IEA
ENST00000344900 Clstn1 Calsyntenin-1 precursor related cluster 4699 0.0 93% (890/956) GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IEA; GO:0007155|cell adhesion|IEA; GO:0007156|homophilic cell adhesion|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000345034 Unassigned protein
ENST00000345038 Agrn Agrin precursor related cluster 9830 0.0 90% (1820/2020) GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|TAS; GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IPI; GO:0005605|basal lamina|IDA; GO:0007155|cell adhesion|IEA; GO:0007165|signal transduction|TAS; GO:0007213|acetylcholine receptor signaling, muscarinic pathway|TAS; GO:0043113|receptor clustering|IDA; GO:0043113|receptor clustering|IMP; GO:0043236|laminin binding|TAS; GO:0045162|clustering of voltage-gated sodium channels|TAS; GO:0050808|synapse organization and biogenesis|TAS
ENST00000346436 Clcn6 Chloride channel protein 6 related cluster 348 1e-145 78% (66/84) Inorganic ion transport and metabolism GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS
ENST00000347370 UB2J2 Ubiquitin-conjugating enzyme E2 J2 related cluster 1305 1e-143 95% (248/259) 6.3.2.19 Posttranslational modification, protein turnover, chaperones GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA
ENST00000348298 UB2J2 Ubiquitin-conjugating enzyme E2 J2 related cluster 1079 1e-117 94% (206/217) 6.3.2.19 Posttranslational modification, protein turnover, chaperones GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA
ENST00000348549 Casp9 Casp9; caspase 9 [EC:3.4.22.-] [KO:K04399] 412 3e-39 71% (100/139) 3.4.22.- Apoptosis MAPK signaling pathway
ENST00000349152 Tnfrsf1b Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b) (Etanercept) [Contains: Tumor necrosis factor binding protein 2 (TBPII) (TBP-2)] related cluster 1918 0.0 89% (359/403) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006915|apoptosis|IEA; GO:0016021|integral to membrane|IEA; GO:0019221|cytokine and chemokine mediated signaling pathway|IEA
ENST00000353409 Kif1b Kinesin-like protein KIF1B related cluster 8231 0.0 89% (1620/1803) Cytoskeleton GO:0003774|motor activity|IEA; GO:0003777|microtubule motor activity|ISS; GO:0005515|protein binding|ISS; GO:0005524|ATP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0005875|microtubule associated complex|IEA; GO:0005875|microtubule associated complex|ISS; GO:0007018|microtubule-based movement|ISS; GO:0007270|nerve-nerve synaptic transmission|ISS; GO:0007274|neuromuscular synaptic transmission|ISS; GO:0008017|microtubule binding|ISS; GO:0008089|anterograde axon cargo transport|ISS; GO:0009790|embryonic development|ISS; GO:0016887|ATPase activity|ISS; GO:0019894|kinesin binding|TAS; GO:0030659|cytoplasmic vesicle membrane|ISS; GO:0030705|cytoskeleton-dependent intracellular transport|ISS
ENST00000354700 Centb5 Centaurin beta 5 related cluster 1023 1e-110 100% (204/204) GO:0005096|GTPase activator activity|IEA; GO:0043087|regulation of GTPase activity|IEA
ENST00000356315 Vps13d Vps13d; vacuolar protein sorting 13D (yeast) 19514 0.0 90% (3794/4214) Intracellular trafficking, secretion, and vesicular transport
ENST00000356876 Tnfrsf25 Tumor necrosis factor receptor superfamily member 25 precursor related cluster 2064 0.0 88% (368/417) Cytokine-cytokine receptor interaction GO:0004872|receptor activity|IEA; GO:0004872|receptor activity|NAS; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005515|protein binding|IEA; GO:0005829|cytosol|NAS; GO:0005887|integral to plasma membrane|TAS; GO:0006915|apoptosis|IEA; GO:0006915|apoptosis|NAS; GO:0006917|induction of apoptosis|TAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0007166|cell surface receptor linked signal transduction|TAS; GO:0008624|induction of apoptosis by extracellular signals|TAS; GO:0016021|integral to membrane|IEA; GO:0042981|regulation of apoptosis|NAS
ENST00000357399 Clcnk1l Clcnk1l; chloride channel K1-like [KO:K05018] 2627 0.0 74% (504/681) Inorganic ion transport and metabolism
ENST00000357898 LOC313722 SPRY domain-containing SOCS box protein SSB-1 related cluster 1470 1e-163 100% (273/273) GO:0007242|intracellular signaling cascade|IEA
ENST00000358432 Epha2 Epha2; Eph receptor A2 [EC:2.7.1.112] [KO:K05103] 4593 0.0 91% (869/952) 2.7.1.112
ENST00000358481 LOC298595 LOC298595; similar to Peptidyl arginine deiminase, egg and embryo abundant 2516 0.0 68% (468/685)
ENST00000358663 UB2J2 Ubiquitin-conjugating enzyme E2 J2 related cluster 309 1e-26 98% (57/58) 6.3.2.19 Posttranslational modification, protein turnover, chaperones Parkinson's disease GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA
ENST00000358874 ENOA Alpha enolase related cluster 2219 0.0 100% (433/433) 4.2.1.11 Carbohydrate transport and metabolism Glycolysis / Gluconeogenesis Phenylalanine, tyrosine and tryptophan biosynthesis GO:0000015|phosphopyruvate hydratase complex|IEA; GO:0000287|magnesium ion binding|IEA; GO:0004634|phosphopyruvate hydratase activity|IEA; GO:0004634|phosphopyruvate hydratase activity|TAS; GO:0006096|glycolysis|IEA; GO:0016829|lyase activity|IEA
ENST00000359090 LOC433810 LOC433810; similar to transmembrane protein SHREW1 638 2e-65 92% (125/135)
ENST00000360001 45 kDa calcium-binding protein precursor related cluster 205 1e-129 76% (40/52) GO:0005509|calcium ion binding|IEA; GO:0005794|Golgi apparatus|IEA
ENST00000360142 Hp1bp3 Heterochromatin protein 1, binding protein 3 related cluster 1829 0.0 70% (391/553) GO:0000786|nucleosome|IEA; GO:0003677|DNA binding|IEA; GO:0005634|nucleus|IEA; GO:0006334|nucleosome assembly|IEA
ENST00000360393 Polymyositis/scleroderma autoantigen 2 related cluster 4369 0.0 95% (844/885) GO:0003676|nucleic acid binding|IEA; GO:0003723|RNA binding|IEA; GO:0004518|nuclease activity|IEA; GO:0004527|exonuclease activity|IEA; GO:0004674|protein serine/threonine kinase activity|TAS; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005730|nucleolus|TAS; GO:0006364|rRNA processing|IEA; GO:0008408|3'-5' exonuclease activity|IEA; GO:0016787|hydrolase activity|IEA
ENST00000360563 Pik3cd Phosphatidylinositol 3-kinase delta catalytic subunit related cluster 5011 0.0 90% (964/1068) 2.7.1.153 Apoptosis Inositol phosphate metabolism Jak-STAT signaling pathway Phosphatidylinositol signaling system Regulation of actin cytoskeleton Toll-like receptor signaling pathway GO:0004428|inositol or phosphatidylinositol kinase activity|IEA; GO:0005942|phosphoinositide 3-kinase complex|IEA; GO:0007165|signal transduction|IEA; GO:0016301|kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA
ENST00000361311 Clstn1 Calsyntenin-1 precursor related cluster 4630 0.0 93% (880/946) GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IEA; GO:0007155|cell adhesion|IEA; GO:0007156|homophilic cell adhesion|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA
ENST00000361445 Frap1 FKBP12-rapamycin complex-associated protein related cluster 12200 0.0 93% (2376/2549) GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA
ENST00000361521 BACH Cytosolic acyl coenzyme A thioester hydrolase related cluster 473 4e-46 100% (93/93) 3.1.2.2 Lipid transport and metabolism GO:0000062|acyl-CoA binding|TAS; GO:0003824|catalytic activity|IEA; GO:0003824|catalytic activity|TAS; GO:0004759|serine esterase activity|IEA; GO:0005737|cytoplasm|TAS; GO:0006629|lipid metabolism|TAS; GO:0016290|palmitoyl-CoA hydrolase activity|IEA; GO:0016787|hydrolase activity|IEA
ENST00000361640 Akr7a5 Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) 1399 1e-155 81% (260/318)
ENST00000361827 Masp2 Mannan-binding lectin serine protease 2 precursor related cluster 960 1e-103 95% (173/181) Complement and coagulation cascades GO:0004252|serine-type endopeptidase activity|IEA; GO:0004252|serine-type endopeptidase activity|TAS; GO:0004263|chymotrypsin activity|IEA; GO:0004295|trypsin activity|IEA; GO:0005509|calcium ion binding|IEA; GO:0005576|extracellular region|IEA; GO:0006508|proteolysis and peptidolysis|IEA; GO:0006956|complement activation|IEA; GO:0006956|complement activation|TAS; GO:0006958|complement activation, classical pathway|IEA; GO:0008233|peptidase activity|IEA; GO:0008236|serine-type peptidase activity|TAS; GO:0016787|hydrolase activity|IEA; GO:0019735|antimicrobial humoral response (sensu Vertebrata)|TAS
ENST00000361923 Per3 Period circadian protein 3 related cluster 5342 0.0 87% (1040/1187) GO:0004871|signal transducer activity|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007165|signal transduction|IEA; GO:0048511|rhythmic process|IEA
ENST00000361947 Frap1 FKBP12-rapamycin complex-associated protein related cluster 12187 0.0 93% (2376/2551) GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA
ENST00000362035 ICMT Protein-S-isoprenylcysteine O-methyltransferase related cluster 1303 1e-143 90% (246/273) 2.1.1.100 Posttranslational modification, protein turnover, chaperones GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA