Ssequence id |
Locus |
Description |
Alignment Score |
E-value |
% Sequence Identity |
EC number |
COG Function |
KEGG Pathways |
GeneOntology |
ENST00000009120
|
|
Metalloprotease mmp21/22A related cluster |
1727 |
0.0 |
92% (317/342) |
|
|
|
GO:0000004|biological_process unknown|ND; GO:0004222|metalloendopeptidase activity|IEA; GO:0004222|metalloendopeptidase activity|ISS; GO:0004222|metalloendopeptidase activity|NAS; GO:0005578|extracellular matrix (sensu Metazoa)|IEA; GO:0005578|extracellular matrix (sensu Metazoa)|NAS; GO:0005622|intracellular|ISS; GO:0006508|proteolysis and peptidolysis|IEA; GO:0008233|peptidase activity|IEA; GO:0008237|metallopeptidase activity|IEA; GO:0008270|zinc ion binding|ISS |
ENST00000011700
|
Vps13d |
Vps13d; vacuolar protein sorting 13D (yeast) |
19676 |
0.0 |
90% (3820/4239) |
|
Intracellular trafficking, secretion, and vesicular transport |
|
|
ENST00000029717
|
Tnfrsf1b |
Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b) (Etanercept) [Contains: Tumor necrosis factor binding protein 2 (TBPII) (TBP-2)] related cluster |
2133 |
0.0 |
90% (397/441) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006915|apoptosis|IEA; GO:0016021|integral to membrane|IEA; GO:0019221|cytokine and chemokine mediated signaling pathway|IEA |
ENST00000054661
|
G6PE |
GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6- phosphogluconolactonase (EC 3.1.1.31) (6PGL)] related cluster |
4156 |
0.0 |
99% (790/791) |
1.1.1.47 |
Carbohydrate transport and metabolism |
|
GO:0003824|catalytic activity|IEA; GO:0004345|glucose-6-phosphate 1-dehydrogenase activity|IEA; GO:0004345|glucose-6-phosphate 1-dehydrogenase activity|TAS; GO:0005489|electron transporter activity|NR; GO:0005783|endoplasmic reticulum|IEA; GO:0005975|carbohydrate metabolism|IEA; GO:0006006|glucose metabolism|IEA; GO:0006098|pentose-phosphate shunt|IEA; GO:0016491|oxidoreductase activity|IEA; GO:0016787|hydrolase activity|IEA; GO:0017057|6-phosphogluconolactonase activity|IEA; GO:0047936|glucose 1-dehydrogenase activity|IEA |
ENST00000054668
|
Uts2 |
Urotensin-2 precursor related cluster |
529 |
3e-53 |
86% (106/122) |
|
|
Neuroactive ligand-receptor interaction |
GO:0005102|receptor binding|TAS; GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|TAS; GO:0005576|extracellular region|IEA; GO:0005615|extracellular space|TAS; GO:0006936|muscle contraction|TAS; GO:0007268|synaptic transmission|TAS; GO:0008217|regulation of blood pressure|TAS |
ENST00000054670
|
Tnfrsf9 |
Tumor necrosis factor receptor superfamily member 9 precursor related cluster |
1259 |
1e-138 |
91% (226/246) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0004872|receptor activity|TAS; GO:0005887|integral to plasma membrane|TAS; GO:0006917|induction of apoptosis|TAS; GO:0006955|immune response|NR; GO:0008285|negative regulation of cell proliferation|TAS; GO:0016021|integral to membrane|IEA |
ENST00000062030
|
Akr7a5 |
Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) |
1338 |
1e-148 |
77% (250/323) |
|
|
|
|
ENST00000062038
|
|
[J] COG0244 Ribosomal protein L10 |
493 |
1e-49 |
50% (103/202) |
|
Translation, ribosomal structure and biogenesis |
|
|
ENST00000072205
|
LOC230872 |
LOC230872; rootletin |
5386 |
0.0 |
63% (1212/1919) |
|
|
|
|
ENST00000160698
|
Trp73 |
Tumor protein p73 related cluster |
3237 |
0.0 |
95% (608/636) |
|
|
|
GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|IEA; GO:0003700|transcription factor activity|TAS; GO:0005515|protein binding|IPI; GO:0005634|nucleus|IEA; GO:0006298|mismatch repair|TAS; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0006915|apoptosis|IEA; GO:0008630|DNA damage response, signal transduction resulting in induction of apoptosis|TAS; GO:0045786|negative regulation of cell cycle|IEA |
ENST00000164247
|
Kcnab2 |
Voltage-gated potassium channel beta-2 subunit (K(+) channel beta-2 subunit) related cluster |
1906 |
0.0 |
100% (367/367) |
|
|
|
GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005249|voltage-gated potassium channel activity|IEA; GO:0005737|cytoplasm|IEA; GO:0005737|cytoplasm|NR; GO:0006811|ion transport|IEA; GO:0006813|potassium ion transport|IEA; GO:0015459|potassium channel regulator activity|TAS; GO:0016021|integral to membrane|IEA |
ENST00000168666
|
Per3 |
Period circadian protein 3 related cluster |
5354 |
0.0 |
86% (1037/1196) |
|
|
|
GO:0004871|signal transducer activity|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007165|signal transduction|IEA; GO:0048511|rhythmic process|IEA |
ENST00000196061
|
PLOD1 |
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor related cluster |
3804 |
0.0 |
97% (711/727) |
1.14.11.4 |
|
Lysine degradation |
GO:0005489|electron transporter activity|NAS; GO:0005489|electron transporter activity|NR; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|NAS; GO:0008475|procollagen-lysine 5-dioxygenase activity|IEA; GO:0008544|epidermis development|TAS; GO:0016020|membrane|IEA; GO:0016491|oxidoreductase activity|IEA; GO:0016702|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|IEA; GO:0016706|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|IEA; GO:0019538|protein metabolism|IEA |
ENST00000234487
|
Clcn6 |
Chloride channel protein 6 related cluster |
3954 |
0.0 |
90% (766/848) |
|
Inorganic ion transport and metabolism |
|
GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS |
ENST00000234490
|
Dnajc11 |
Dnajc11; DnaJ (Hsp40) homolog, subfamily C, member 11 |
1553 |
1e-172 |
92% (302/327) |
|
Posttranslational modification, protein turnover, chaperones |
|
|
ENST00000234492
|
Pax7 |
Pax7; paired box gene 7 |
2263 |
0.0 |
91% (430/468) |
|
|
|
|
ENST00000234646
|
Pqlc2 |
Pqlc2; PQ loop repeat containing 2 |
928 |
2e-99 |
86% (179/207) |
|
|
|
|
ENST00000234875
|
Rpl22 |
60S ribosomal protein L22 related cluster |
401 |
1e-37 |
81% (81/99) |
|
|
Ribosome |
GO:0003723|RNA binding|IEA; GO:0003723|RNA binding|TAS; GO:0003735|structural constituent of ribosome|IEA; GO:0003735|structural constituent of ribosome|TAS; GO:0005622|intracellular|IEA; GO:0005840|ribosome|IEA; GO:0005842|cytosolic large ribosomal subunit (sensu Eukaryota)|TAS; GO:0006412|protein biosynthesis|IEA; GO:0006412|protein biosynthesis|TAS; GO:0008201|heparin binding|IEA |
ENST00000234897
|
Phf13 |
PHD finger protein 13 related cluster |
1402 |
1e-154 |
88% (265/300) |
|
|
|
GO:0003677|DNA binding|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA |
ENST00000234909
|
LOC313729 |
Mitogen-inducible gene 6 protein related cluster |
2130 |
0.0 |
89% (412/462) |
|
|
|
GO:0005100|Rho GTPase activator activity|TAS; GO:0005737|cytoplasm|TAS; GO:0006950|response to stress|TAS |
ENST00000234912
|
|
Chain B, Crystal Structure Of The K130r Mutant Of Human Dj-1 pdb|1PE0|A Chain A, Crystal Structure Of The K130r Mutant Of Human Dj-1 |
943 |
1e-100 |
99% (188/189) |
|
|
|
|
ENST00000235287
|
SPEE |
Spermidine synthase related cluster |
1478 |
1e-164 |
97% (281/287) |
2.5.1.16 |
Amino acid transport and metabolism |
Arginine and proline metabolism Urea cycle and metabolism of amino groups beta-Alanine metabolism |
GO:0003824|catalytic activity|IEA; GO:0004766|spermidine synthase activity|IEA; GO:0004766|spermidine synthase activity|TAS; GO:0008295|spermidine biosynthesis|IEA; GO:0008757|S-adenosylmethionine-dependent methyltransferase activity|IEA; GO:0016740|transferase activity|IEA |
ENST00000235299
|
Fbxo2 |
F-box only protein 2 related cluster |
1199 |
1e-131 |
76% (225/296) |
|
|
|
GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|TAS; GO:0005515|protein binding|IEA; GO:0006464|protein modification|TAS; GO:0006508|proteolysis and peptidolysis|TAS; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA |
ENST00000235310
|
Mad2l2 |
Mitotic spindle assembly checkpoint protein MAD2B related cluster |
1043 |
1e-113 |
94% (200/211) |
2.7.7.7 |
|
DNA polymerase |
GO:0007049|cell cycle|IEA; GO:0007067|mitosis|IEA; GO:0007067|mitosis|NAS; GO:0007094|mitotic spindle checkpoint|TAS |
ENST00000235329
|
Mfn2 |
Transmembrane GTPase MFN2 related cluster |
3704 |
0.0 |
96% (729/758) |
|
General function prediction only |
|
GO:0003924|GTPase activity|IEA; GO:0005525|GTP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0016021|integral to membrane|IEA; GO:0016787|hydrolase activity|IEA; GO:0019867|outer membrane|IEA |
ENST00000235332
|
|
IGFBP-2-Binding Protein, IIp45 related cluster |
1727 |
0.0 |
90% (321/353) |
|
|
|
|
ENST00000235372
|
LOC313678 |
LOC313678; similar to zinc finger protein RIZ |
2423 |
0.0 |
74% (473/631) |
|
General function prediction only |
|
|
ENST00000235417
|
LOC298607 |
LOC298607; similar to Agmatinase, mitochondrial precursor (Agmatine ureohydrolase) (AUH) |
1437 |
1e-159 |
83% (274/328) |
|
Amino acid transport and metabolism |
|
|
ENST00000235432
|
Plekhm2 |
Plekhm2; pleckstrin homology domain containing, family M (with RUN domain) member 2 |
4260 |
0.0 |
81% (828/1019) |
|
|
|
|
ENST00000235455
|
Zbtb17 |
Zbtb17; zinc finger and BTB domain containing 17 |
3480 |
0.0 |
83% (661/788) |
|
General function prediction only |
|
|
ENST00000235768
|
Sdhb |
Sdhb; succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [EC:1.3.5.1] [KO:K00235] |
1347 |
1e-149 |
89% (250/278) |
1.3.5.1 |
Energy production and conversion |
Citrate cycle (TCA cycle) Oxidative phosphorylation |
|
ENST00000235772
|
Mfap2 |
Mfap2; microfibrillar-associated protein 2 |
660 |
2e-68 |
81% (122/150) |
|
|
|
|
ENST00000235799
|
|
actin |
565 |
4e-57 |
35% (127/357) |
|
Cytoskeleton |
|
|
ENST00000235835
|
Akr7a5 |
Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) |
1569 |
1e-175 |
86% (297/343) |
|
|
|
|
ENST00000235865
|
Pla2g5 |
Pla2g5; phospholipase A2, group V [EC:3.1.1.4] [KO:K01047] |
512 |
3e-51 |
68% (94/137) |
3.1.1.4 |
|
Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism |
|
ENST00000235867
|
Pla2g2d |
Pla2g2d; phospholipase A2, group IID [EC:3.1.1.4] [KO:K01047] |
625 |
5e-64 |
71% (103/145) |
3.1.1.4 |
|
Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism |
|
ENST00000235894
|
Ddost |
Ddost; dolichyl-di-phosphooligosaccharide-protein glycotransferase [EC:2.4.1.119] [KO:K00730] |
2037 |
0.0 |
94% (392/417) |
2.4.1.119 |
|
N-Glycan biosynthesis |
|
ENST00000240174
|
Nppb |
Natriuretic peptides B precursor [Contains: Gamma-brain natriuretic peptide; Brain natriuretic peptide 32 (BNP-32)] related cluster |
619 |
1e-63 |
90% (121/134) |
|
|
|
GO:0005102|receptor binding|IPI; GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|NAS; GO:0005576|extracellular region|IEA; GO:0005576|extracellular region|TAS; GO:0005615|extracellular space|NAS; GO:0007166|cell surface receptor linked signal transduction|NAS; GO:0007589|fluid secretion|TAS; GO:0008217|regulation of blood pressure|NAS; GO:0008613|diuretic hormone activity|TAS; GO:0016525|negative regulation of angiogenesis|TAS; GO:0030146|diuresis|TAS; GO:0030147|natriuresis|TAS; GO:0030308|negative regulation of cell growth|NAS; GO:0042312|regulation of vasodilation|NAS; GO:0043114|regulation of vascular permeability|TAS |
ENST00000240179
|
LOC313706 |
Transitional epithelia response protein related cluster |
1616 |
1e-180 |
94% (319/338) |
|
|
|
GO:0016020|membrane|IEA |
ENST00000240185
|
Tardbp |
TAR DNA-binding protein-43 related cluster |
1543 |
1e-171 |
74% (308/414) |
|
General function prediction only |
|
GO:0000398|nuclear mRNA splicing, via spliceosome|IEA; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|TAS; GO:0003723|RNA binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0006366|transcription from Pol II promoter|TAS; GO:0006397|mRNA processing|IEA; GO:0007067|mitosis|TAS; GO:0008017|microtubule binding|TAS |
ENST00000241542
|
Mint |
Mint; Msx2 interacting nuclear target protein |
11585 |
0.0 |
67% (2423/3596) |
|
|
|
|
ENST00000244841
|
Pin |
Pin; dynein, cytoplasmic, light chain 1 |
419 |
4e-41 |
87% (78/89) |
|
|
|
|
ENST00000245530
|
Padi2 |
Padi2; peptidyl arginine deiminase, type II [EC:3.5.3.15] |
3321 |
0.0 |
93% (623/665) |
3.5.3.15 |
|
|
|
ENST00000246421
|
|
Unassigned protein |
|
|
|
|
|
|
|
ENST00000246422
|
|
[G] COG0061 Predicted sugar kinase |
495 |
3e-49 |
39% (104/261) |
|
Carbohydrate transport and metabolism |
|
|
ENST00000247986
|
Kif17 |
Kif17; kinesin family member 17 |
3962 |
0.0 |
78% (806/1028) |
|
Cytoskeleton |
|
|
ENST00000248008
|
LOC313658 |
LOC313658; similar to retinoblastoma-associated factor 600 |
23413 |
0.0 |
89% (4598/5155) |
|
|
|
|
ENST00000248017
|
LOC298581 |
LOC298581; similar to group IIE secreted phospholipase A2 |
674 |
1e-70 |
90% (112/124) |
|
|
|
|
ENST00000251544
|
Fbxo6b |
F-box only protein 6 related cluster |
1531 |
1e-170 |
95% (281/293) |
|
|
|
GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA |
ENST00000251546
|
Fbxo44 |
F-box only protein 44 related cluster |
492 |
1e-112 |
100% (87/87) |
|
|
|
GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA |
ENST00000251547
|
Fbxo44 |
F-box only protein 44 related cluster |
1313 |
1e-144 |
94% (237/250) |
|
|
|
GO:0005515|protein binding|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0030163|protein catabolism|IEA |
ENST00000253251
|
Ube4b |
Ubiquitin conjugation factor E4 B related cluster |
5281 |
0.0 |
87% (1030/1173) |
|
Posttranslational modification, protein turnover, chaperones |
|
GO:0000151|ubiquitin ligase complex|IEA; GO:0000151|ubiquitin ligase complex|TAS; GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0004842|ubiquitin-protein ligase activity|TAS; GO:0005515|protein binding|IPI; GO:0005737|cytoplasm|IDA; GO:0006457|protein folding|NAS; GO:0006511|ubiquitin-dependent protein catabolism|TAS; GO:0006512|ubiquitin cycle|IEA; GO:0006915|apoptosis|ISS; GO:0008151||NAS; GO:0009411|response to UV|ISS; GO:0016567|protein ubiquitination|IEA; GO:0019899|enzyme binding|IPI; GO:0042787|protein ubiquitination during ubiquitin-dependent protein catabolism|TAS; GO:0051082|unfolded protein binding|NAS |
ENST00000253887
|
Mrpl20 |
Mitochondrial ribosomal protein L20 related cluster |
771 |
1e-81 |
100% (149/149) |
|
Translation, ribosomal structure and biogenesis |
|
GO:0003723|RNA binding|IEA; GO:0003735|structural constituent of ribosome|IEA; GO:0005622|intracellular|IEA; GO:0005840|ribosome|IEA; GO:0006412|protein biosynthesis|IEA; GO:0019843|rRNA binding|IEA; GO:0030529|ribonucleoprotein complex|IEA |
ENST00000253987
|
CAH6 |
Carbonic anhydrase VI precursor related cluster |
1593 |
1e-177 |
95% (295/308) |
4.2.1.1 |
Inorganic ion transport and metabolism |
Nitrogen metabolism |
GO:0004089|carbonate dehydratase activity|IEA; GO:0004089|carbonate dehydratase activity|TAS; GO:0006730|one-carbon compound metabolism|IEA; GO:0008270|zinc ion binding|IEA; GO:0016829|lyase activity|IEA |
ENST00000253998
|
|
Nephrocystin 4 related cluster |
321 |
6e-28 |
100% (59/59) |
|
|
|
GO:0005198|structural molecule activity|NAS; GO:0005515|protein binding|IPI; GO:0007165|signal transduction|NAS; GO:0007632|visual behavior|NAS; GO:0016020|membrane|IC; GO:0016337|cell-cell adhesion|NAS; GO:0030036|actin cytoskeleton organization and biogenesis|NAS |
ENST00000255573
|
LOC298578 |
LOC298578; similar to Group IIF secretory phospholipase A2 precursor (Phosphatidylcholine 2-acylhydrolase GIIF) (GIIF sPLA2) (sPLA(2)-IIF) |
853 |
1e-90 |
66% (156/236) |
|
|
|
|
ENST00000262450
|
Chd5 |
Chromodomain helicase-DNA-binding protein 5 related cluster |
8272 |
0.0 |
82% (1606/1950) |
|
|
|
GO:0000151|ubiquitin ligase complex|IEA; GO:0000785|chromatin|IEA; GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA; GO:0003682|chromatin binding|IEA; GO:0004386|helicase activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0006333|chromatin assembly or disassembly|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008026|ATP-dependent helicase activity|IEA; GO:0008270|zinc ion binding|IEA; GO:0016567|protein ubiquitination|IEA; GO:0016568|chromatin modification|IEA |
ENST00000263495
|
|
Putative MAPK activating protein related cluster |
609 |
4e-62 |
92% (122/132) |
|
|
|
|
ENST00000263741
|
|
45 kDa calcium-binding protein precursor related cluster |
307 |
1e-26 |
98% (58/59) |
|
|
|
GO:0005509|calcium ion binding|IEA; GO:0005794|Golgi apparatus|IEA |
ENST00000263743
|
Dvl1 |
Segment polarity protein dishevelled homolog DVL-1 related cluster |
175 |
1e-149 |
100% (35/35) |
|
|
Wnt signaling pathway |
GO:0003677|DNA binding|IEA; GO:0004871|signal transducer activity|IEA; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005737|cytoplasm|TAS; GO:0007165|signal transduction|TAS; GO:0007222|frizzled signaling pathway|IEA; GO:0007242|intracellular signaling cascade|IEA; GO:0007275|development|IEA; GO:0007507|heart development|TAS; GO:0009653|morphogenesis|TAS; GO:0016055|Wnt receptor signaling pathway|IEA |
ENST00000263746
|
Atad3a |
AAA-ATPase TOB3 related cluster |
2440 |
0.0 |
76% (501/654) |
|
General function prediction only |
|
GO:0000166|nucleotide binding|IEA; GO:0005524|ATP binding|IEA; GO:0017111|nucleoside-triphosphatase activity|IEA |
ENST00000263750
|
Gnb1 |
Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 related cluster |
177 |
4e-11 |
25% (53/210) |
|
|
|
GO:0004871|signal transducer activity|IEA; GO:0007165|signal transduction|IEA |
ENST00000263932
|
Tnfrsf8 |
Tumor necrosis factor receptor superfamily member 8 precursor related cluster |
2845 |
0.0 |
89% (531/593) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0004888|transmembrane receptor activity|TAS; GO:0007165|signal transduction|TAS; GO:0008285|negative regulation of cell proliferation|TAS; GO:0016021|integral to membrane|IEA |
ENST00000263934
|
Kif1b |
Kinesin-like protein KIF1B related cluster |
8121 |
0.0 |
90% (1610/1770) |
|
Cytoskeleton |
|
GO:0003774|motor activity|IEA; GO:0003777|microtubule motor activity|ISS; GO:0005515|protein binding|ISS; GO:0005524|ATP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0005875|microtubule associated complex|IEA; GO:0005875|microtubule associated complex|ISS; GO:0007018|microtubule-based movement|ISS; GO:0007270|nerve-nerve synaptic transmission|ISS; GO:0007274|neuromuscular synaptic transmission|ISS; GO:0008017|microtubule binding|ISS; GO:0008089|anterograde axon cargo transport|ISS; GO:0009790|embryonic development|ISS; GO:0016887|ATPase activity|ISS; GO:0019894|kinesin binding|TAS; GO:0030659|cytoplasmic vesicle membrane|ISS; GO:0030705|cytoskeleton-dependent intracellular transport|ISS |
ENST00000264203
|
Capzb |
Capzb; F-actin capping protein beta subunit |
1415 |
1e-156 |
100% (271/271) |
|
|
|
|
ENST00000264205
|
ECE1 |
Endothelin-converting enzyme 1 related cluster |
3997 |
0.0 |
97% (750/770) |
3.4.24.71 |
|
|
GO:0004222|metalloendopeptidase activity|TAS; GO:0004245|neprilysin activity|IEA; GO:0005624|membrane fraction|TAS; GO:0006508|proteolysis and peptidolysis|IEA; GO:0007267|cell-cell signaling|NR; GO:0008237|metallopeptidase activity|IEA; GO:0008270|zinc ion binding|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|TAS; GO:0016512|endothelin-converting enzyme 1 activity|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000264206
|
Usp48 |
Ubiquitin-specific protease 31 related cluster |
5402 |
0.0 |
98% (1016/1035) |
|
Posttranslational modification, protein turnover, chaperones |
|
GO:0004197|cysteine-type endopeptidase activity|IEA; GO:0004221|ubiquitin thiolesterase activity|IEA; GO:0006511|ubiquitin-dependent protein catabolism|IEA; GO:0008233|peptidase activity|IEA |
ENST00000270684
|
Slc2a5 |
Solute carrier family 2, facilitated glucose transporter, member 5 related cluster |
2185 |
0.0 |
88% (441/501) |
|
|
|
GO:0005215|transporter activity|IEA; GO:0005351|sugar porter activity|IEA; GO:0005353|fructose transporter activity|IEA; GO:0005353|fructose transporter activity|TAS; GO:0005355|glucose transporter activity|IEA; GO:0005355|glucose transporter activity|TAS; GO:0005886|plasma membrane|TAS; GO:0005975|carbohydrate metabolism|TAS; GO:0006810|transport|IEA; GO:0008643|carbohydrate transport|IEA; GO:0015755|fructose transport|TAS; GO:0015758|glucose transport|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000270685
|
LOC435818 |
Intestinal facilitative glucose transporter 7 related cluster |
2479 |
0.0 |
93% (491/524) |
|
|
|
GO:0005215|transporter activity|IEA; GO:0005351|sugar porter activity|IEA; GO:0005355|glucose transporter activity|IEA; GO:0006810|transport|IEA; GO:0008643|carbohydrate transport|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000270691
|
Espn |
Espn; espin |
854 |
6e-91 |
63% (196/308) |
|
|
|
|
ENST00000270708
|
Wdr8 |
WD-repeat protein 8 related cluster |
2483 |
0.0 |
100% (460/460) |
|
General function prediction only |
|
|
ENST00000270722
|
|
PR-domain zinc finger protein 16 related cluster |
6181 |
0.0 |
91% (1170/1275) |
|
General function prediction only |
|
GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IC; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|NAS; GO:0005634|nucleus|IC; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IC; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008270|zinc ion binding|IEA |
ENST00000270728
|
Ela2 |
Ela2; elastase 2 [EC:3.4.21.71] |
1220 |
1e-134 |
83% (224/269) |
3.4.21.71 |
Posttranslational modification, protein turnover, chaperones |
|
|
ENST00000270733
|
Padi3 |
Padi3; peptidyl arginine deiminase, type III [EC:3.5.3.15] |
3151 |
0.0 |
87% (581/663) |
3.5.3.15 |
|
|
|
ENST00000270737
|
Padi1 |
Padi1; peptidyl arginine deiminase, type I [EC:3.5.3.15] |
2673 |
0.0 |
75% (501/662) |
3.5.3.15 |
|
|
|
ENST00000270747
|
Arhgef19 |
Arhgef19; Rho guanine nucleotide exchange factor (GEF) 19 |
3151 |
0.0 |
79% (634/801) |
|
Signal transduction mechanisms |
|
|
ENST00000270750
|
LOC298609 |
LOC298609; similar to Swiprosin 1 |
799 |
2e-84 |
71% (171/238) |
|
|
|
|
ENST00000270774
|
Pex14 |
Peroxisomal membrane protein PEX14 related cluster |
1355 |
1e-149 |
76% (276/362) |
|
|
|
GO:0005777|peroxisome|IEA; GO:0005777|peroxisome|TAS; GO:0005779|integral to peroxisomal membrane|TAS; GO:0016020|membrane|IEA |
ENST00000270776
|
6PGD |
6-phosphogluconate dehydrogenase, decarboxylating related cluster |
2431 |
0.0 |
97% (464/475) |
1.1.1.44 |
Carbohydrate transport and metabolism |
Pentose phosphate pathway |
GO:0004616|phosphogluconate dehydrogenase (decarboxylating) activity|IEA; GO:0005489|electron transporter activity|TAS; GO:0006098|pentose-phosphate shunt|IEA; GO:0009051|pentose-phosphate shunt, oxidative branch|TAS; GO:0016491|oxidoreductase activity|IEA |
ENST00000288032
|
Epha2 |
Epha2; Eph receptor A2 [EC:2.7.1.112] [KO:K05103] |
4593 |
0.0 |
91% (869/952) |
2.7.1.112 |
|
|
|
ENST00000288660
|
LOC302697 |
LOC302697; similar to Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (eIF-4C) |
510 |
2e-51 |
98% (97/98) |
|
Translation, ribosomal structure and biogenesis |
|
|
ENST00000288709
|
|
PREDICTED: similar to membrane metallo-endopeptidase-like 2 [Canis familiaris] |
3280 |
0.0 |
86% (612/710) |
|
Posttranslational modification, protein turnover, chaperones |
|
|
ENST00000288726
|
Tnfrsf14 |
Tumor necrosis factor receptor superfamily member 14 precursor related cluster |
1578 |
1e-175 |
100% (283/283) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0004888|transmembrane receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005887|integral to plasma membrane|IC; GO:0006915|apoptosis|IEA; GO:0006955|immune response|IEA; GO:0006955|immune response|TAS; GO:0007165|signal transduction|IEA; GO:0007166|cell surface receptor linked signal transduction|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000288738
|
PANK4 |
Pantothenate kinase 4 related cluster |
3749 |
0.0 |
94% (729/771) |
2.7.1.33 |
Coenzyme transport and metabolism |
|
GO:0004594|pantothenate kinase activity|IEA; GO:0005524|ATP binding|IEA; GO:0015937|coenzyme A biosynthesis|IEA; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA |
ENST00000288774
|
|
Peroxisome assembly protein 10 related cluster |
1224 |
1e-134 |
72% (244/337) |
|
|
|
GO:0000151|ubiquitin ligase complex|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005777|peroxisome|IEA; GO:0005778|peroxisomal membrane|NAS; GO:0007031|peroxisome organization and biogenesis|IDA; GO:0008270|zinc ion binding|IEA; GO:0008270|zinc ion binding|NAS; GO:0016020|membrane|IEA; GO:0016558|peroxisome matrix protein import|IDA; GO:0016567|protein ubiquitination|IEA |
ENST00000288796
|
Ski |
Ski oncogene related cluster |
2738 |
0.0 |
76% (546/711) |
|
|
|
GO:0005554|molecular_function unknown|ND; GO:0005634|nucleus|IEA; GO:0005634|nucleus|NAS; GO:0008151||IEA; GO:0030154|cell differentiation|NAS |
ENST00000288816
|
KPCZ |
Protein kinase C, zeta type related cluster |
3151 |
0.0 |
99% (589/590) |
2.7.1.37 |
|
Calcium signaling pathway MAPK signaling pathway Phosphatidylinositol signaling system Wnt signaling pathway |
GO:0004672|protein kinase activity|IEA; GO:0004672|protein kinase activity|TAS; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0004700|atypical protein kinase C activity|TAS; GO:0005524|ATP binding|IEA; GO:0005624|membrane fraction|TAS; GO:0005737|cytoplasm|TAS; GO:0005886|plasma membrane|TAS; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006468|protein amino acid phosphorylation|TAS; GO:0006916|anti-apoptosis|TAS; GO:0007165|signal transduction|TAS; GO:0007242|intracellular signaling cascade|IEA; GO:0016740|transferase activity|IEA; GO:0019992|diacylglycerol binding|IEA |
ENST00000289226
|
Gpr153 |
G protein-coupled receptor 153 related cluster |
2479 |
0.0 |
80% (493/609) |
|
|
|
GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004872|receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0016021|integral to membrane|IEA |
ENST00000289749
|
Nbl1 |
Nbl1; neuroblastoma, suppression of tumorigenicity 1 |
677 |
3e-70 |
80% (128/160) |
|
|
|
|
ENST00000289753
|
Htr6 |
Htr6; 5-hydroxytryptamine (serotonin) receptor 6 [KO:K04162] |
1576 |
1e-175 |
73% (322/440) |
|
|
Calcium signaling pathway Neuroactive ligand-receptor interaction |
|
ENST00000289839
|
LOC362638 |
LOC362638; similar to CYTIDINE DEAMINASE (CYTIDINE AMINOHYDROLASE) |
663 |
5e-69 |
82% (119/144) |
|
Nucleotide transport and metabolism |
|
|
ENST00000289840
|
LOC298575 |
LOC298575; similar to protein kinase BRPK [KO:K05688] |
2307 |
0.0 |
80% (450/560) |
|
|
Neurodegenerative Disorders Parkinson's disease |
|
ENST00000289877
|
|
Proton-associated sugar transporter A related cluster |
2291 |
0.0 |
89% (448/498) |
|
|
|
GO:0005351|sugar porter activity|IEA; GO:0006810|transport|IEA; GO:0015293|symporter activity|IEA; GO:0016021|integral to membrane|IEA |
ENST00000290507
|
Padi4 |
Padi4; peptidyl arginine deiminase, type IV [EC:3.5.3.15] |
2553 |
0.0 |
72% (480/663) |
3.5.3.15 |
|
|
|
ENST00000290597
|
Aldh4a1 |
Aldh4a1; aldehyde dehydrogenase 4 family, member A1 |
2720 |
0.0 |
92% (505/547) |
|
Energy production and conversion |
|
|
ENST00000291355
|
Dffa |
DNA fragmentation factor alpha subunit related cluster |
1586 |
1e-176 |
95% (317/331) |
|
|
Apoptosis |
GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS |
ENST00000294399
|
LOC362668 |
Krueppel-related zinc finger protein 3 related cluster |
3557 |
0.0 |
96% (663/688) |
|
General function prediction only |
|
GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|TAS; GO:0005515|protein binding|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0008270|zinc ion binding|IEA |
ENST00000294427
|
LOC362653 |
[O] COG5640 Secreted trypsin-like serine protease |
241 |
3e-20 |
30% (73/240) |
|
Posttranslational modification, protein turnover, chaperones |
|
|
ENST00000294431
|
Lzic |
Leucine zipper & ICAT homologous protein LZIC related cluster |
709 |
5e-74 |
81% (154/190) |
|
|
|
GO:0007275|development|IEA; GO:0008013|beta-catenin binding|IEA |
ENST00000294435
|
Rbp7 |
Retinol-binding protein IV, cellular related cluster |
726 |
3e-76 |
100% (134/134) |
|
|
|
GO:0005215|transporter activity|IEA; GO:0005488|binding|IEA; GO:0006810|transport|IEA; GO:0008289|lipid binding|IEA; GO:0019841|retinol binding|IEA |
ENST00000294450
|
Cal |
Cal; CSX-associated LIM |
1280 |
1e-141 |
66% (248/373) |
|
|
|
|
ENST00000294489
|
Gp38 |
Gp38; glycoprotein 38 |
211 |
2e-15 |
36% (59/162) |
|
|
|
|
ENST00000294492
|
Dhrs3 |
Dhrs3; dehydrogenase/reductase (SDR family) member 3 |
1488 |
1e-165 |
95% (287/302) |
|
|
|
|
ENST00000294544
|
Ubxd3 |
Ubxd3; UBX domain containing 3 |
906 |
1e-96 |
65% (183/280) |
|
|
|
|
ENST00000294546
|
LOC287005 |
LOC287005; CaM-kinase II inhibitor alpha |
333 |
3e-30 |
82% (64/78) |
|
|
|
|
ENST00000294599
|
Egfl3 |
Multiple EGF-like-domain protein 3 related cluster |
7106 |
0.0 |
96% (1188/1237) |
|
|
|
GO:0000004|biological_process unknown|ND; GO:0005198|structural molecule activity|IEA; GO:0005509|calcium ion binding|IEA; GO:0005509|calcium ion binding|NAS; GO:0008372|cellular_component unknown|ND |
ENST00000302666
|
PK3CD |
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform related cluster |
4960 |
0.0 |
90% (949/1044) |
2.7.1.153 |
|
Apoptosis Inositol phosphate metabolism Jak-STAT signaling pathway Phosphatidylinositol signaling system Regulation of actin cytoskeleton Toll-like receptor signaling pathway |
GO:0004428|inositol or phosphatidylinositol kinase activity|IEA; GO:0005942|phosphoinositide 3-kinase complex|IEA; GO:0005942|phosphoinositide 3-kinase complex|NAS; GO:0006468|protein amino acid phosphorylation|NAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|NAS; GO:0016301|kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|NAS; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA; GO:0046934|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|IEA |
ENST00000302692
|
|
Mitochondrial carrier protein MGC4399 related cluster |
1613 |
1e-180 |
100% (316/316) |
|
|
|
GO:0005488|binding|IEA; GO:0005743|mitochondrial inner membrane|IEA; GO:0006810|transport|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000303152
|
Dffb |
DNA fragmentation factor 40 kDa subunit related cluster |
1789 |
0.0 |
100% (338/338) |
3.-.-.- |
|
Apoptosis |
GO:0004518|nuclease activity|IEA; GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS; GO:0016787|hydrolase activity|IEA |
ENST00000304185
|
PUSL1 |
Pseudouridylate synthase-like 1 related cluster |
1460 |
1e-162 |
95% (282/294) |
4.2.1.70 |
Translation, ribosomal structure and biogenesis |
|
GO:0004730|pseudouridylate synthase activity|IEA; GO:0008033|tRNA processing|IEA; GO:0016829|lyase activity|IEA |
ENST00000304436
|
Angpt1 |
Angiopoietin-4 precursor related cluster |
512 |
1e-50 |
36% (108/297) |
|
|
|
GO:0000004|biological_process unknown|ND; GO:0005554|molecular_function unknown|ND; GO:0030297|transmembrane receptor protein tyrosine kinase activator activity|NAS |
ENST00000304457
|
|
Polymyositis/scleroderma autoantigen 2 related cluster |
4203 |
0.0 |
95% (819/860) |
|
|
|
GO:0003676|nucleic acid binding|IEA; GO:0003723|RNA binding|IEA; GO:0004518|nuclease activity|IEA; GO:0004527|exonuclease activity|IEA; GO:0004674|protein serine/threonine kinase activity|TAS; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005730|nucleolus|TAS; GO:0006364|rRNA processing|IEA; GO:0008408|3'-5' exonuclease activity|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000304706
|
Arpm2 |
Actin related protein M2 related cluster |
1972 |
0.0 |
100% (377/377) |
|
Cytoskeleton |
|
GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|IEA; GO:0015629|actin cytoskeleton|IEA |
ENST00000306256
|
LOC298675 |
LOC298675; similar to RER1 homolog |
1029 |
1e-111 |
96% (189/196) |
|
|
|
|
ENST00000307786
|
|
Calglandulin-like protein related cluster |
820 |
5e-87 |
100% (164/164) |
|
|
|
GO:0005509|calcium ion binding|IEA |
ENST00000308271
|
Usp48 |
Ubiquitin-specific protease 31 related cluster |
5065 |
0.0 |
98% (963/982) |
|
Posttranslational modification, protein turnover, chaperones |
|
GO:0004197|cysteine-type endopeptidase activity|IEA; GO:0004221|ubiquitin thiolesterase activity|IEA; GO:0006511|ubiquitin-dependent protein catabolism|IEA; GO:0008233|peptidase activity|IEA |
ENST00000308647
|
Atad3a |
AAA-ATPase TOB3 related cluster |
2662 |
0.0 |
93% (522/556) |
|
|
|
GO:0000166|nucleotide binding|IEA; GO:0005524|ATP binding|IEA; GO:0017111|nucleoside-triphosphatase activity|IEA |
ENST00000309212
|
|
Limitrin related cluster |
1809 |
0.0 |
79% (351/442) |
|
|
|
|
ENST00000311890
|
Hspb7 |
Hspb7; heat shock protein family, member 7 (cardiovascular) |
660 |
4e-68 |
92% (129/140) |
|
|
|
|
ENST00000312301
|
Nppa |
Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide) (ANP) (Prepronatriodilatin) [Contains: Cardiodilatin-related peptide (CDP)] related cluster |
623 |
4e-64 |
89% (119/133) |
|
|
|
GO:0005179|hormone activity|IEA; GO:0005179|hormone activity|NAS; GO:0005576|extracellular region|IEA; GO:0005576|extracellular region|NAS; GO:0007582|physiological process|IEA; GO:0008217|regulation of blood pressure|IDA |
ENST00000312413
|
Clcn6 |
Chloride channel protein 6 related cluster |
1365 |
1e-150 |
89% (266/297) |
|
Inorganic ion transport and metabolism |
|
GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS |
ENST00000314340
|
Agtrap |
AGTRAP protein related cluster |
823 |
2e-87 |
100% (158/158) |
|
|
|
|
ENST00000315234
|
ICMT |
Protein-S-isoprenylcysteine O-methyltransferase related cluster |
1303 |
1e-143 |
90% (246/273) |
2.1.1.100 |
Posttranslational modification, protein turnover, chaperones |
|
GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA |
ENST00000315901
|
Rbp7 |
Retinol-binding protein IV, cellular related cluster |
126 |
9e-06 |
100% (24/24) |
|
|
|
GO:0005215|transporter activity|IEA; GO:0005488|binding|IEA; GO:0006810|transport|IEA; GO:0008289|lipid binding|IEA; GO:0019841|retinol binding|IEA |
ENST00000317137
|
LOC298675 |
LOC298675; similar to RER1 homolog |
383 |
1e-107 |
93% (69/74) |
|
|
|
|
ENST00000317673
|
CD2L1 |
PITSLRE serine/threonine-protein kinase CDC2L1 related cluster |
574 |
3e-58 |
71% (120/167) |
2.7.1.37 |
|
|
GO:0000074|regulation of cell cycle|IEP; GO:0001558|regulation of cell growth|IEP; GO:0004672|protein kinase activity|IEA; GO:0004674|protein serine/threonine kinase activity|IDA; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0005524|ATP binding|IDA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|IEP; GO:0006468|protein amino acid phosphorylation|IDA; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006915|apoptosis|IEA; GO:0007049|cell cycle|IEA; GO:0007067|mitosis|NAS; GO:0016740|transferase activity|IEA; GO:0050684|regulation of mRNA processing|IDA |
ENST00000317967
|
LOC313644 |
Rap1 GTPase-activating protein 1 related cluster |
3149 |
0.0 |
91% (607/664) |
|
|
|
GO:0005096|GTPase activator activity|IEA; GO:0005096|GTPase activator activity|TAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0016020|membrane|IEA |
ENST00000319254
|
|
G protein-coupled receptor 157 related cluster |
594 |
5e-61 |
73% (114/155) |
|
|
|
GO:0004872|receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0016020|membrane|IEA |
ENST00000320153
|
ddi2 |
ddi2; DNA-damage inducible protein 2 |
1505 |
1e-167 |
77% (305/394) |
|
|
|
|
ENST00000320485
|
Cort |
CORT related cluster |
700 |
6e-73 |
86% (133/154) |
|
|
Neuroactive ligand-receptor interaction |
GO:0005179|hormone activity|IEA; GO:0005576|extracellular region|IEA |
ENST00000320498
|
Cort |
Cortistatin, isoform d related cluster |
420 |
5e-40 |
100% (83/83) |
|
|
Neuroactive ligand-receptor interaction |
GO:0003677|DNA binding|IEA |
ENST00000321729
|
MGC94202 |
Aurora-A kinase interacting protein related cluster |
1054 |
1e-114 |
100% (199/199) |
|
|
|
GO:0005515|protein binding|IPI; GO:0005634|nucleus|IDA; GO:0005634|nucleus|IEA; GO:0045839|negative regulation of mitosis|NAS |
ENST00000322762
|
LOC298683 |
Von Willebrand factor A domain-related protein, isoform 1 related cluster |
1817 |
0.0 |
82% (365/445) |
|
|
|
|
ENST00000323338
|
MTHR |
Methylenetetrahydrofolate reductase related cluster |
3259 |
0.0 |
93% (612/656) |
1.5.1.20 |
Amino acid transport and metabolism |
One carbon pool by folate |
GO:0003824|catalytic activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|TAS; GO:0006520|amino acid metabolism|TAS; GO:0006555|methionine metabolism|IEA; GO:0008015|circulation|TAS; GO:0016491|oxidoreductase activity|IEA |
ENST00000323910
|
Thap1 |
THAP domain protein 3 related cluster |
770 |
7e-81 |
95% (146/153) |
|
|
|
GO:0003676|nucleic acid binding|IEA; GO:0003677|DNA binding|IEA |
ENST00000325267
|
Tas1r2 |
Tas1r2; taste receptor, type 1, member 2 [KO:K04625] |
2954 |
0.0 |
64% (543/838) |
|
|
|
|
ENST00000325764
|
Catnbip1 |
Beta-catenin-interacting protein 1 related cluster |
405 |
7e-38 |
100% (81/81) |
|
|
Wnt signaling pathway |
GO:0005515|protein binding|TAS; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|TAS; GO:0007165|signal transduction|TAS; GO:0007275|development|IEA; GO:0007275|development|TAS; GO:0008013|beta-catenin binding|IEA; GO:0008283|cell proliferation|TAS; GO:0016055|Wnt receptor signaling pathway|IEA |
ENST00000326183
|
Olfr1289 |
Olfactory receptor 4F4 related cluster |
1480 |
1e-164 |
94% (287/305) |
|
|
|
GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA |
ENST00000326216
|
B3galt6 |
B3galt6; UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6 [EC:2.4.1.134] [KO:K00734] |
1070 |
1e-116 |
77% (202/262) |
2.4.1.134 |
|
Chondroitin / Heparan sulfate biosynthesis |
|
ENST00000327169
|
Olr777 |
Olfactory receptor 4F3 related cluster |
1540 |
1e-171 |
95% (297/312) |
|
|
|
GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA |
ENST00000328565
|
Tnfrsf4 |
Tumor necrosis factor receptor superfamily member 4 precursor related cluster |
1248 |
1e-137 |
87% (223/254) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005887|integral to plasma membrane|TAS; GO:0006955|immune response|TAS; GO:0016021|integral to membrane|IEA |
ENST00000328596
|
Tnfrsf18 |
Tumor necrosis factor receptor superfamily member 18 precursor related cluster |
119 |
6e-05 |
61% (24/39) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006916|anti-apoptosis|TAS; GO:0007165|signal transduction|TAS; GO:0016021|integral to membrane|IEA |
ENST00000330361
|
Pla2g2a |
Pla2g2a; phospholipase A2, group IIA (platelets, synovial fluid) [EC:3.1.1.4] [KO:K01047] |
506 |
2e-50 |
65% (95/144) |
3.1.1.4 |
|
Glycerolipid metabolism MAPK signaling pathway Phospholipid degradation Prostaglandin and leukotriene metabolism |
|
ENST00000331433
|
Clcnk1 |
Clcnk1; chloride channel K1 [KO:K05017] |
2709 |
0.0 |
76% (521/680) |
|
Inorganic ion transport and metabolism |
|
|
ENST00000332831
|
Olr777 |
Olfactory receptor 4F3 related cluster |
1540 |
1e-171 |
95% (297/312) |
|
|
|
GO:0001584|rhodopsin-like receptor activity|IEA; GO:0004930|G-protein coupled receptor activity|IEA; GO:0004984|olfactory receptor activity|IEA; GO:0007186|G-protein coupled receptor protein signaling pathway|IEA; GO:0007608|perception of smell|IEA; GO:0016021|integral to membrane|IEA |
ENST00000333868
|
Casp9 |
Casp9; caspase 9 [EC:3.4.22.-] [KO:K04399] |
1574 |
1e-175 |
76% (318/416) |
3.4.22.- |
|
Apoptosis MAPK signaling pathway |
|
ENST00000334429
|
Mst1 |
Mst1; Macrophage stimulating 1 (hepatocyte growth factor-like) |
2488 |
0.0 |
74% (462/620) |
|
|
|
|
ENST00000334998
|
Mst1 |
Mst1; macrophage stimulating 1 (hepatocyte growth factor-like) |
1242 |
1e-136 |
77% (222/286) |
|
|
|
|
ENST00000335808
|
BACH |
Cytosolic acyl coenzyme A thioester hydrolase related cluster |
1665 |
0.0 |
97% (327/336) |
3.1.2.2 |
Lipid transport and metabolism |
|
GO:0000062|acyl-CoA binding|TAS; GO:0003824|catalytic activity|IEA; GO:0003824|catalytic activity|TAS; GO:0004759|serine esterase activity|IEA; GO:0005737|cytoplasm|TAS; GO:0006629|lipid metabolism|TAS; GO:0016290|palmitoyl-CoA hydrolase activity|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000336114
|
Cort |
CORT related cluster |
387 |
4e-36 |
98% (71/72) |
|
|
Neuroactive ligand-receptor interaction |
GO:0005179|hormone activity|IEA; GO:0005576|extracellular region|IEA |
ENST00000337061
|
CD2L1 |
PITSLRE serine/threonine-protein kinase CDC2L1 related cluster |
2770 |
0.0 |
72% (567/783) |
2.7.1.37 |
|
|
GO:0000074|regulation of cell cycle|IEP; GO:0001558|regulation of cell growth|IEP; GO:0004672|protein kinase activity|IEA; GO:0004674|protein serine/threonine kinase activity|IDA; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0005524|ATP binding|IDA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|IEP; GO:0006468|protein amino acid phosphorylation|IDA; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006915|apoptosis|IEA; GO:0007049|cell cycle|IEA; GO:0007067|mitosis|NAS; GO:0016740|transferase activity|IEA; GO:0050684|regulation of mRNA processing|IDA |
ENST00000337265
|
Nbl1 |
Nbl1; neuroblastoma, suppression of tumorigenicity 1 |
677 |
3e-70 |
80% (128/160) |
|
|
|
|
ENST00000337639
|
Aldh4a1 |
Aldh4a1; aldehyde dehydrogenase 4 family, member A1 |
2720 |
0.0 |
92% (505/547) |
|
Energy production and conversion |
|
|
ENST00000337907
|
Rere |
RERE related cluster |
4980 |
0.0 |
65% (1006/1535) |
|
|
Dentatorubropallidoluysian atrophy (DRPLA) |
GO:0000004|biological_process unknown|ND; GO:0003677|DNA binding|IEA; GO:0003700|transcription factor activity|IEA; GO:0005515|protein binding|NAS; GO:0005634|nucleus|IEA; GO:0005634|nucleus|NAS; GO:0006355|regulation of transcription, DNA-dependent|IEA |
ENST00000338555
|
Scnn1a |
Amiloride-sensitive sodium channel delta-subunit related cluster |
3144 |
0.0 |
92% (588/638) |
|
|
|
GO:0005216|ion channel activity|IEA; GO:0005272|sodium channel activity|IEA; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|NR; GO:0006811|ion transport|IEA; GO:0006814|sodium ion transport|IEA; GO:0006814|sodium ion transport|TAS; GO:0015280|amiloride-sensitive sodium channel activity|IEA; GO:0015280|amiloride-sensitive sodium channel activity|TAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000338591
|
|
Kelch-like protein 17 related cluster |
3033 |
0.0 |
94% (592/626) |
|
|
|
GO:0003779|actin binding|IEA; GO:0005515|protein binding|IEA |
ENST00000338639
|
|
Chain B, Crystal Structure Of The K130r Mutant Of Human Dj-1 pdb|1PE0|A Chain A, Crystal Structure Of The K130r Mutant Of Human Dj-1 |
943 |
1e-100 |
99% (188/189) |
|
|
|
|
ENST00000339380
|
LOC298683 |
Von Willebrand factor A domain-related protein, isoform 1 related cluster |
1105 |
1e-120 |
78% (226/289) |
|
|
|
|
ENST00000340401
|
Arhgef16 |
Neuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster |
2004 |
0.0 |
93% (393/421) |
|
Signal transduction mechanisms |
|
|
ENST00000340468
|
|
Ubiquitin cross-reactive protein precursor related cluster |
733 |
4e-77 |
93% (144/154) |
|
Posttranslational modification, protein turnover, chaperones |
|
GO:0005515|protein binding|NAS; GO:0005615|extracellular space|NAS; GO:0005737|cytoplasm|NAS; GO:0006955|immune response|IEA; GO:0007267|cell-cell signaling|NAS |
ENST00000342010
|
NMNA1 |
Nicotinamide mononucleotide adenylyltransferase 1 related cluster |
1458 |
1e-161 |
100% (279/279) |
2.7.7.1 |
Coenzyme transport and metabolism |
|
GO:0000287|magnesium ion binding|IEA; GO:0000309|nicotinamide-nucleotide adenylyltransferase activity|IDA; GO:0000309|nicotinamide-nucleotide adenylyltransferase activity|IEA; GO:0005515|protein binding|IPI; GO:0005634|nucleus|IDA; GO:0005634|nucleus|IEA; GO:0006736|NADH biosynthesis|IDA; GO:0009058|biosynthesis|IEA; GO:0009435|NAD biosynthesis|IEA; GO:0016740|transferase activity|IEA; GO:0016779|nucleotidyltransferase activity|IEA; GO:0019363|pyridine nucleotide biosynthesis|IEA |
ENST00000342066
|
Samd11 |
Sterile alpha motif domain containing 11 related cluster |
2055 |
0.0 |
82% (411/496) |
|
|
|
|
ENST00000343008
|
Hes1 |
Transcription factor HES-4 related cluster |
656 |
6e-68 |
88% (134/151) |
|
|
|
GO:0003677|DNA binding|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007275|development|IEA; GO:0007399|neurogenesis|IEA |
ENST00000343090
|
Ube4b |
Ubiquitin conjugation factor E4 B related cluster |
5714 |
0.0 |
86% (1125/1301) |
|
Posttranslational modification, protein turnover, chaperones |
|
GO:0000151|ubiquitin ligase complex|IEA; GO:0000151|ubiquitin ligase complex|TAS; GO:0004840|ubiquitin conjugating enzyme activity|TAS; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005737|cytoplasm|ISS; GO:0006457|protein folding|ISS; GO:0006512|ubiquitin cycle|IEA; GO:0006915|apoptosis|IDA; GO:0008151||ISS; GO:0009411|response to UV|IDA; GO:0016567|protein ubiquitination|IEA; GO:0019899|enzyme binding|ISS; GO:0042787|protein ubiquitination during ubiquitin-dependent protein catabolism|TAS; GO:0051082|unfolded protein binding|ISS |
ENST00000343579
|
Espn |
Espin related cluster |
780 |
9e-82 |
50% (196/386) |
|
|
|
GO:0005903|brush border|TAS; GO:0005929|cilium|IDA; GO:0015629|actin cytoskeleton|IDA; GO:0030046|parallel actin filament bundle formation|IDA; GO:0051017|actin filament bundle formation|IDA |
ENST00000343813
|
ICMT |
Protein-S-isoprenylcysteine O-methyltransferase related cluster |
286 |
1e-137 |
67% (57/84) |
2.1.1.100 |
Posttranslational modification, protein turnover, chaperones |
|
GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA |
ENST00000344115
|
Gabrd |
Gamma-aminobutyric-acid receptor delta subunit precursor (GABA(A) receptor) related cluster |
2106 |
0.0 |
94% (409/433) |
|
|
Neuroactive ligand-receptor interaction |
GO:0004890|GABA-A receptor activity|IEA; GO:0004890|GABA-A receptor activity|TAS; GO:0005216|ion channel activity|IEA; GO:0005230|extracellular ligand-gated ion channel activity|IEA; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|IEA; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0007165|signal transduction|TAS; GO:0007268|synaptic transmission|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0030594|neurotransmitter receptor activity|IEA; GO:0045211|postsynaptic membrane|IEA |
ENST00000344365
|
|
UPF0120 protein DKFZp564C186 related cluster |
3405 |
0.0 |
90% (668/736) |
|
|
|
GO:0005554|molecular_function unknown|IEA; GO:0005634|nucleus|IEA |
ENST00000344573
|
PPBT |
Alkaline phosphatase, tissue-nonspecific isozyme precursor related cluster |
2631 |
0.0 |
99% (496/497) |
3.1.3.1 |
Inorganic ion transport and metabolism |
Folate biosynthesis Glycerolipid metabolism gamma-Hexachlorocyclohexane degradation |
GO:0000287|magnesium ion binding|IEA; GO:0001501|skeletal development|TAS; GO:0001503|ossification|IEA; GO:0004035|alkaline phosphatase activity|IEA; GO:0008152|metabolism|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000344900
|
Clstn1 |
Calsyntenin-1 precursor related cluster |
4699 |
0.0 |
93% (890/956) |
|
|
|
GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IEA; GO:0007155|cell adhesion|IEA; GO:0007156|homophilic cell adhesion|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000345034
|
|
Unassigned protein |
|
|
|
|
|
|
|
ENST00000345038
|
Agrn |
Agrin precursor related cluster |
9830 |
0.0 |
90% (1820/2020) |
|
|
|
GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|TAS; GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IPI; GO:0005605|basal lamina|IDA; GO:0007155|cell adhesion|IEA; GO:0007165|signal transduction|TAS; GO:0007213|acetylcholine receptor signaling, muscarinic pathway|TAS; GO:0043113|receptor clustering|IDA; GO:0043113|receptor clustering|IMP; GO:0043236|laminin binding|TAS; GO:0045162|clustering of voltage-gated sodium channels|TAS; GO:0050808|synapse organization and biogenesis|TAS |
ENST00000346436
|
Clcn6 |
Chloride channel protein 6 related cluster |
348 |
1e-145 |
78% (66/84) |
|
Inorganic ion transport and metabolism |
|
GO:0005216|ion channel activity|IEA; GO:0005244|voltage-gated ion channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|IEA; GO:0005247|voltage-gated chloride channel activity|NAS; GO:0005254|chloride channel activity|TAS; GO:0005624|membrane fraction|NR; GO:0005887|integral to plasma membrane|TAS; GO:0006810|transport|TAS; GO:0006811|ion transport|IEA; GO:0006821|chloride transport|IEA; GO:0006821|chloride transport|NAS; GO:0006884|regulation of cell volume|NAS; GO:0007165|signal transduction|NAS; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA; GO:0016021|integral to membrane|NAS |
ENST00000347370
|
UB2J2 |
Ubiquitin-conjugating enzyme E2 J2 related cluster |
1305 |
1e-143 |
95% (248/259) |
6.3.2.19 |
Posttranslational modification, protein turnover, chaperones |
|
GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA |
ENST00000348298
|
UB2J2 |
Ubiquitin-conjugating enzyme E2 J2 related cluster |
1079 |
1e-117 |
94% (206/217) |
6.3.2.19 |
Posttranslational modification, protein turnover, chaperones |
|
GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA |
ENST00000348549
|
Casp9 |
Casp9; caspase 9 [EC:3.4.22.-] [KO:K04399] |
412 |
3e-39 |
71% (100/139) |
3.4.22.- |
|
Apoptosis MAPK signaling pathway |
|
ENST00000349152
|
Tnfrsf1b |
Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b) (Etanercept) [Contains: Tumor necrosis factor binding protein 2 (TBPII) (TBP-2)] related cluster |
1918 |
0.0 |
89% (359/403) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|IEA; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0006915|apoptosis|IEA; GO:0016021|integral to membrane|IEA; GO:0019221|cytokine and chemokine mediated signaling pathway|IEA |
ENST00000353409
|
Kif1b |
Kinesin-like protein KIF1B related cluster |
8231 |
0.0 |
89% (1620/1803) |
|
Cytoskeleton |
|
GO:0003774|motor activity|IEA; GO:0003777|microtubule motor activity|ISS; GO:0005515|protein binding|ISS; GO:0005524|ATP binding|IEA; GO:0005739|mitochondrion|IEA; GO:0005875|microtubule associated complex|IEA; GO:0005875|microtubule associated complex|ISS; GO:0007018|microtubule-based movement|ISS; GO:0007270|nerve-nerve synaptic transmission|ISS; GO:0007274|neuromuscular synaptic transmission|ISS; GO:0008017|microtubule binding|ISS; GO:0008089|anterograde axon cargo transport|ISS; GO:0009790|embryonic development|ISS; GO:0016887|ATPase activity|ISS; GO:0019894|kinesin binding|TAS; GO:0030659|cytoplasmic vesicle membrane|ISS; GO:0030705|cytoskeleton-dependent intracellular transport|ISS |
ENST00000354700
|
Centb5 |
Centaurin beta 5 related cluster |
1023 |
1e-110 |
100% (204/204) |
|
|
|
GO:0005096|GTPase activator activity|IEA; GO:0043087|regulation of GTPase activity|IEA |
ENST00000356315
|
Vps13d |
Vps13d; vacuolar protein sorting 13D (yeast) |
19514 |
0.0 |
90% (3794/4214) |
|
Intracellular trafficking, secretion, and vesicular transport |
|
|
ENST00000356876
|
Tnfrsf25 |
Tumor necrosis factor receptor superfamily member 25 precursor related cluster |
2064 |
0.0 |
88% (368/417) |
|
|
Cytokine-cytokine receptor interaction |
GO:0004872|receptor activity|IEA; GO:0004872|receptor activity|NAS; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005515|protein binding|IEA; GO:0005829|cytosol|NAS; GO:0005887|integral to plasma membrane|TAS; GO:0006915|apoptosis|IEA; GO:0006915|apoptosis|NAS; GO:0006917|induction of apoptosis|TAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0007166|cell surface receptor linked signal transduction|TAS; GO:0008624|induction of apoptosis by extracellular signals|TAS; GO:0016021|integral to membrane|IEA; GO:0042981|regulation of apoptosis|NAS |
ENST00000357399
|
Clcnk1l |
Clcnk1l; chloride channel K1-like [KO:K05018] |
2627 |
0.0 |
74% (504/681) |
|
Inorganic ion transport and metabolism |
|
|
ENST00000357898
|
LOC313722 |
SPRY domain-containing SOCS box protein SSB-1 related cluster |
1470 |
1e-163 |
100% (273/273) |
|
|
|
GO:0007242|intracellular signaling cascade|IEA |
ENST00000358432
|
Epha2 |
Epha2; Eph receptor A2 [EC:2.7.1.112] [KO:K05103] |
4593 |
0.0 |
91% (869/952) |
2.7.1.112 |
|
|
|
ENST00000358481
|
LOC298595 |
LOC298595; similar to Peptidyl arginine deiminase, egg and embryo abundant |
2516 |
0.0 |
68% (468/685) |
|
|
|
|
ENST00000358663
|
UB2J2 |
Ubiquitin-conjugating enzyme E2 J2 related cluster |
309 |
1e-26 |
98% (57/58) |
6.3.2.19 |
Posttranslational modification, protein turnover, chaperones |
Parkinson's disease |
GO:0004840|ubiquitin conjugating enzyme activity|IEA; GO:0004842|ubiquitin-protein ligase activity|IEA; GO:0005783|endoplasmic reticulum|IEA; GO:0006464|protein modification|IEA; GO:0006512|ubiquitin cycle|IEA; GO:0016021|integral to membrane|IEA; GO:0016874|ligase activity|IEA |
ENST00000358874
|
ENOA |
Alpha enolase related cluster |
2219 |
0.0 |
100% (433/433) |
4.2.1.11 |
Carbohydrate transport and metabolism |
Glycolysis / Gluconeogenesis Phenylalanine, tyrosine and tryptophan biosynthesis |
GO:0000015|phosphopyruvate hydratase complex|IEA; GO:0000287|magnesium ion binding|IEA; GO:0004634|phosphopyruvate hydratase activity|IEA; GO:0004634|phosphopyruvate hydratase activity|TAS; GO:0006096|glycolysis|IEA; GO:0016829|lyase activity|IEA |
ENST00000359090
|
LOC433810 |
LOC433810; similar to transmembrane protein SHREW1 |
638 |
2e-65 |
92% (125/135) |
|
|
|
|
ENST00000360001
|
|
45 kDa calcium-binding protein precursor related cluster |
205 |
1e-129 |
76% (40/52) |
|
|
|
GO:0005509|calcium ion binding|IEA; GO:0005794|Golgi apparatus|IEA |
ENST00000360142
|
Hp1bp3 |
Heterochromatin protein 1, binding protein 3 related cluster |
1829 |
0.0 |
70% (391/553) |
|
|
|
GO:0000786|nucleosome|IEA; GO:0003677|DNA binding|IEA; GO:0005634|nucleus|IEA; GO:0006334|nucleosome assembly|IEA |
ENST00000360393
|
|
Polymyositis/scleroderma autoantigen 2 related cluster |
4369 |
0.0 |
95% (844/885) |
|
|
|
GO:0003676|nucleic acid binding|IEA; GO:0003723|RNA binding|IEA; GO:0004518|nuclease activity|IEA; GO:0004527|exonuclease activity|IEA; GO:0004674|protein serine/threonine kinase activity|TAS; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005730|nucleolus|TAS; GO:0006364|rRNA processing|IEA; GO:0008408|3'-5' exonuclease activity|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000360563
|
Pik3cd |
Phosphatidylinositol 3-kinase delta catalytic subunit related cluster |
5011 |
0.0 |
90% (964/1068) |
2.7.1.153 |
|
Apoptosis Inositol phosphate metabolism Jak-STAT signaling pathway Phosphatidylinositol signaling system Regulation of actin cytoskeleton Toll-like receptor signaling pathway |
GO:0004428|inositol or phosphatidylinositol kinase activity|IEA; GO:0005942|phosphoinositide 3-kinase complex|IEA; GO:0007165|signal transduction|IEA; GO:0016301|kinase activity|IEA; GO:0016303|phosphatidylinositol 3-kinase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA |
ENST00000361311
|
Clstn1 |
Calsyntenin-1 precursor related cluster |
4630 |
0.0 |
93% (880/946) |
|
|
|
GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IEA; GO:0007155|cell adhesion|IEA; GO:0007156|homophilic cell adhesion|IEA; GO:0016020|membrane|IEA; GO:0016021|integral to membrane|IEA |
ENST00000361445
|
Frap1 |
FKBP12-rapamycin complex-associated protein related cluster |
12200 |
0.0 |
93% (2376/2549) |
|
|
|
GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA |
ENST00000361521
|
BACH |
Cytosolic acyl coenzyme A thioester hydrolase related cluster |
473 |
4e-46 |
100% (93/93) |
3.1.2.2 |
Lipid transport and metabolism |
|
GO:0000062|acyl-CoA binding|TAS; GO:0003824|catalytic activity|IEA; GO:0003824|catalytic activity|TAS; GO:0004759|serine esterase activity|IEA; GO:0005737|cytoplasm|TAS; GO:0006629|lipid metabolism|TAS; GO:0016290|palmitoyl-CoA hydrolase activity|IEA; GO:0016787|hydrolase activity|IEA |
ENST00000361640
|
Akr7a5 |
Akr7a5; aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) |
1399 |
1e-155 |
81% (260/318) |
|
|
|
|
ENST00000361827
|
Masp2 |
Mannan-binding lectin serine protease 2 precursor related cluster |
960 |
1e-103 |
95% (173/181) |
|
|
Complement and coagulation cascades |
GO:0004252|serine-type endopeptidase activity|IEA; GO:0004252|serine-type endopeptidase activity|TAS; GO:0004263|chymotrypsin activity|IEA; GO:0004295|trypsin activity|IEA; GO:0005509|calcium ion binding|IEA; GO:0005576|extracellular region|IEA; GO:0006508|proteolysis and peptidolysis|IEA; GO:0006956|complement activation|IEA; GO:0006956|complement activation|TAS; GO:0006958|complement activation, classical pathway|IEA; GO:0008233|peptidase activity|IEA; GO:0008236|serine-type peptidase activity|TAS; GO:0016787|hydrolase activity|IEA; GO:0019735|antimicrobial humoral response (sensu Vertebrata)|TAS |
ENST00000361923
|
Per3 |
Period circadian protein 3 related cluster |
5342 |
0.0 |
87% (1040/1187) |
|
|
|
GO:0004871|signal transducer activity|IEA; GO:0005634|nucleus|IEA; GO:0006355|regulation of transcription, DNA-dependent|IEA; GO:0007165|signal transduction|IEA; GO:0048511|rhythmic process|IEA |
ENST00000361947
|
Frap1 |
FKBP12-rapamycin complex-associated protein related cluster |
12187 |
0.0 |
93% (2376/2551) |
|
|
|
GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA |
ENST00000362035
|
ICMT |
Protein-S-isoprenylcysteine O-methyltransferase related cluster |
1303 |
1e-143 |
90% (246/273) |
2.1.1.100 |
Posttranslational modification, protein turnover, chaperones |
|
GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA |