Detailed annotation info for ENST00000291355; DNA fragmentation factor alpha subunit (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD). [Source:Uniprot/SWISSPROT;Acc:O00273]
| Annotation Name | DNA fragmentation factor alpha subunit related cluster | |||||||||
| Score | 1586&emsp | |||||||||
| E-value | 1e-176 | |||||||||
| % Sequence Identity | 95% (317/331) | |||||||||
| Locus | Dffa | |||||||||
| EC Number | ||||||||||
| COG Function | ||||||||||
| KEGG Pathway | Apoptosis | |||||||||
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_O00273 | DNA fragmentation factor alpha subunit related cluster | 1586 | 1e-176 | 95% (317/331) | 1 | GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS | |||
| nr | BAA24140 | ICAD-L [Mus musculus] sp|O54786|DFFA_MOUSE DNA fragmentation factor alpha subunit (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) | 1222 | 1e-132 | 72% (238/329) | 5 | ||||
| cog | No hits found | 0 | ||||||||
| kegg | rno:114214 | Dffa; DNA fragmentation factor, alpha subunit [KO:K02310] | 986 | 1e-106 | 74% (194/262) | Dffa | 2 | Apoptosis | ||
| smart | 00266 | smart00266, CAD, Domains present in proteins implicated in post-mortem DNA fragmentation; | 286 | 3e-27 | 52% (40/76) | CAD | 1 | |||
| pfam | PF02017 | pfam02017, CIDE-N, CIDE-N domain | 291 | 2e-26 | 50% (40/80) | CIDE-N | 1 | |||