Detailed annotation info for ENST00000348549; Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease activating factor 3) (APAF-3). [Source:Uniprot/SWISSPROT;Acc:P55211]
Annotation NameCasp9; caspase 9 [EC:3.4.22.-] [KO:K04399]
Score412&emsp
E-value3e-39
% Sequence Identity71% (100/139)
LocusCasp9
EC Number3.4.22.-
COG Function
KEGG Pathway Apoptosis MAPK signaling pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90
nr1JXQChain D, Structure Of Cleaved, Card Domain Deleted Caspase-9 pdb|1JXQ|C Chain C, Structure Of Cleaved, Card Domain Deleted Caspase-9 pdb|1JXQ|B Chain B, Structure Of Cleaved, Card Domain Deleted Caspase-9 pdb|1JXQ|A Chain A, Structure Of Cleaved, Card Domain Deleted Caspase-96773e-69100% (127/127)4
cogNo hits found0
keggrno:58918Casp9; caspase 9 [EC:3.4.22.-] [KO:K04399]4123e-3971% (100/139)Casp93.4.22.-2 Apoptosis MAPK signaling pathway
smart00115smart00115, CASc, Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine aspartases that mediate programmed cell death (apoptosis)2801e-2630% (39/128)CASc1
smart200114smart00114, CARD, Caspase recruitment domain; Motif contained in proteins involved in apoptotic signalling2281e-2040% (37/92)CARD2
pfamPF00656pfam00656, Peptidase_C14, Caspase domain2463e-2136% (38/103)Peptidase_C141
pfam2PF00619pfam00619, CARD, Caspase recruitment domain2231e-1837% (34/91)CARD2