Detailed annotation info for ENST00000361445; FKBP-rapamycin associated protein (FRAP) (Rapamycin target protein). [Source:Uniprot/SWISSPROT;Acc:P42345]
Annotation NameFKBP12-rapamycin complex-associated protein related cluster
Score12200&emsp
E-value0.0
% Sequence Identity93% (2376/2549)
LocusFrap1
EC Number
COG Function
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90UniRef90_P42345FKBP12-rapamycin complex-associated protein related cluster122000.093% (2376/2549)1GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA
nr2014422AFKBP-rapamycin-associated protein121740.093% (2372/2549)2
cogYKL203c[TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family3685e-3438% (98/257)1
keggrno:56718Frap1; FK506 binding protein 12-rapamycin associated protein 1121280.092% (2360/2549)Frap12
smart00146smart00146, PI3Kc, Phosphoinositide 3-kinase, catalytic domain; Phosphoinositide 3-kinase isoforms participate in a variety of processes, including cell motility, the Ras pathway, vesicle trafficking and secretion, and apoptosis7538e-8135% (106/301)PI3Kc1
smart200689smart00689, DM6, Cysteine-rich domain currently specific to Drosophila995e-0526% (27/102)DM62
pfamPF02259pfam02259, FAT, FAT domain11191e-12231% (199/625)FAT1
pfam2PF00454pfam00454, PI3_PI4_kinase, Phosphatidylinositol 3- and 4-kinase6082e-6236% (91/251)PI3_PI4_kinase2
pfam3PF02260pfam02260, FATC, FATC domain1547e-1057% (19/33)FATC3