Detailed annotation info for ENST00000303152; DNA fragmentation factor 40 kDa subunit (EC 3.-.-.-) (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD) (Caspase-activated nuclease) (CPAN). [Source:Uniprot/SWISSPROT;Acc:O76075]
| Annotation Name | DNA fragmentation factor 40 kDa subunit related cluster | |||||||||
| Score | 1789&emsp | |||||||||
| E-value | 0.0 | |||||||||
| % Sequence Identity | 100% (338/338) | |||||||||
| Locus | Dffb | |||||||||
| EC Number | 3.-.-.- | |||||||||
| COG Function | ||||||||||
| KEGG Pathway | Apoptosis | |||||||||
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_O76075 | DNA fragmentation factor 40 kDa subunit related cluster | 1789 | 0.0 | 100% (338/338) | 1 | GO:0004518|nuclease activity|IEA; GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS; GO:0016787|hydrolase activity|IEA | |||
| nr | BAA24977 | CAD [Mus musculus] sp|O54788|DFFB_MOUSE DNA fragmentation factor 40 kDa subunit (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD) | 1418 | 1e-155 | 77% (262/339) | 3 | ||||
| cog | No hits found | 0 | ||||||||
| kegg | mmu:13368 | Dffb; DNA fragmentation factor, beta subunit [EC:3.-.-.-] [KO:K02311] | 1408 | 1e-155 | 76% (261/339) | Dffb | 3.-.-.- | 1 | Apoptosis | |
| smart | 00266 | smart00266, CAD, Domains present in proteins implicated in post-mortem DNA fragmentation; | 218 | 3e-19 | 44% (33/74) | CAD | 1 | |||
| pfam | PF02017 | pfam02017, CIDE-N, CIDE-N domain | 296 | 9e-27 | 52% (41/78) | CIDE-N | 1 | |||