Detailed annotation info for ENST00000303152; DNA fragmentation factor 40 kDa subunit (EC 3.-.-.-) (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD) (Caspase-activated nuclease) (CPAN). [Source:Uniprot/SWISSPROT;Acc:O76075]
Annotation NameDNA fragmentation factor 40 kDa subunit related cluster
Score1789&emsp
E-value0.0
% Sequence Identity100% (338/338)
LocusDffb
EC Number3.-.-.-
COG Function
KEGG Pathway Apoptosis
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90UniRef90_O76075DNA fragmentation factor 40 kDa subunit related cluster17890.0100% (338/338)1GO:0004518|nuclease activity|IEA; GO:0004537|caspase-activated deoxyribonuclease activity|TAS; GO:0005515|protein binding|IEA; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005634|nucleus|TAS; GO:0005829|cytosol|TAS; GO:0006309|DNA fragmentation during apoptosis|TAS; GO:0006915|apoptosis|IEA; GO:0007242|intracellular signaling cascade|TAS; GO:0016787|hydrolase activity|IEA
nrBAA24977CAD [Mus musculus] sp|O54788|DFFB_MOUSE DNA fragmentation factor 40 kDa subunit (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD)14181e-15577% (262/339)3
cogNo hits found0
keggmmu:13368Dffb; DNA fragmentation factor, beta subunit [EC:3.-.-.-] [KO:K02311]14081e-15576% (261/339)Dffb3.-.-.-1 Apoptosis
smart00266smart00266, CAD, Domains present in proteins implicated in post-mortem DNA fragmentation;2183e-1944% (33/74)CAD1
pfamPF02017pfam02017, CIDE-N, CIDE-N domain2969e-2752% (41/78)CIDE-N1