| Annotation Name | Tumor necrosis factor receptor superfamily member 25 precursor related cluster |
| Score | 2064&emsp |
| E-value | 0.0 |
| % Sequence Identity | 88% (368/417) |
| Locus | Tnfrsf25 |
| EC Number | |
| COG Function | |
| KEGG Pathway | Cytokine-cytokine receptor interaction |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_Q93038 | Tumor necrosis factor receptor superfamily member 25 precursor related cluster | 2064 | 0.0 | 88% (368/417) | | | 1 | | GO:0004872|receptor activity|IEA; GO:0004872|receptor activity|NAS; GO:0005031|tumor necrosis factor receptor activity|TAS; GO:0005515|protein binding|IEA; GO:0005829|cytosol|NAS; GO:0005887|integral to plasma membrane|TAS; GO:0006915|apoptosis|IEA; GO:0006915|apoptosis|NAS; GO:0006917|induction of apoptosis|TAS; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0007166|cell surface receptor linked signal transduction|TAS; GO:0008624|induction of apoptosis by extracellular signals|TAS; GO:0016021|integral to membrane|IEA; GO:0042981|regulation of apoptosis|NAS |
| nr | AAQ88676 | DR3 [Homo sapiens] ref|NP_003781.1| tumor necrosis factor receptor superfamily, member 25 isoform 2 precursor [Homo sapiens] emb|CAI48017.1| unnamed protein product [Homo sapiens] emb|CAI22154.1| tumor necrosis factor receptor superfamily, member 25 [Homo sapiens] gb|AAC51306.1| lymphocyte associated receptor of death 1a [Homo sapiens] gb|AAC50819.1| death receptor 3 [Homo sapiens] gb|AAB40918.1| apoptosis inducing receptor AIR [Homo sapiens] gb|AAB39714.1| Apo-3 [Homo sapiens] sp|Q93038|TR25_HUMAN Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis inducing receptor AIR) (Apo-3) (Lymphocyte associated receptor of death) (LARD) (UNQ455/PRO779) dbj|BAB40662.1| death receptor 3 [Homo sapiens] | 2064 | 0.0 | 88% (368/417) | | | 0 | | |
| cog | | No hits found | | | | | | 0 | | |
| kegg | mmu:85030 | Tnfrsf25; tumor necrosis factor receptor superfamily, member 25 [KO:K05160] | 1235 | 1e-135 | 59% (235/397) | Tnfrsf25 | | 2 | Cytokine-cytokine receptor interaction | |
| smart | 00005 | smart00005, DEATH, DEATH domain, found in proteins involved in cell death (apoptosis) | 191 | 3e-16 | 36% (35/96) | DEATH | | 1 | | |
| smart2 | 00208 | smart00208, TNFR, Tumor necrosis factor receptor / nerve growth factor receptor repeats | 93 | 6e-05 | 34% (15/43) | TNFR | | 2 | | |
| pfam | PF00531 | pfam00531, Death, Death domain | 197 | 1e-15 | 37% (31/82) | Death | | 1 | | |
| pfam2 | PF03154 | pfam03154, Atrophin-1, Atrophin-1 family | 103 | 1e-04 | 21% (100/460) | Atrophin-1 | | 2 | | |