Detailed annotation info for ENST00000345038; Agrin precursor (Fragment). [Source:Uniprot/SPTREMBL;Acc:O00468]
smart900050smart00050, DISIN, Homologues of snake disintegrins ; Snake disintegrins inhibit the binding of ligands to integrin receptors961e-0433% (19/57)DISIN9
pfam8PF03157pfam03157, Glutenin_hmw, High molecular weight glutenin subunit1367e-0823% (96/402)Glutenin_hmw7
pfam9PF03251pfam03251, Tymo_45kd_70kd, Tymovirus 45/70Kd protein1116e-0520% (87/416)Tymo_45kd_70kd8
smart500181smart00181, EGF, Epidermal growth factor-like domain1121e-0645% (17/37)EGF5
smart800157smart00157, PRP, Major prion protein; The prion protein is a major component of scrapie-associated fibrils in Creutzfeldt-Jakob disease, kuru, Gerstmann-Straussler syndrome and bovine spongiform encephalopathy994e-0532% (34/105)PRP8
pfam10PF05790pfam05790, CD2, T-cell surface antigen CD2 protein1171e-0536% (25/68)CD29
smart600179smart00179, EGF_CA, Calcium-binding EGF-like domain;1075e-0647% (17/36)EGF_CA6
smart700057smart00057, FIMAC, factor I membrane attack complex;1022e-0525% (16/64)FIMAC7
Annotation NameAgrin precursor related cluster
Score9830&emsp
E-value0.0
% Sequence Identity90% (1820/2020)
LocusAgrn
EC Number
COG Function
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90UniRef90_O00468Agrin precursor related cluster98300.090% (1820/2020)1GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|TAS; GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IPI; GO:0005605|basal lamina|IDA; GO:0007155|cell adhesion|IEA; GO:0007165|signal transduction|TAS; GO:0007213|acetylcholine receptor signaling, muscarinic pathway|TAS; GO:0043113|receptor clustering|IDA; GO:0043113|receptor clustering|IMP; GO:0043236|laminin binding|TAS; GO:0045162|clustering of voltage-gated sodium channels|TAS; GO:0050808|synapse organization and biogenesis|TAS
nrNP_786930agrin [Rattus norvegicus] gb|AAA40703.1| agrin77320.075% (1422/1888)4
cogYIR019c1331e-0621% (138/629)0
keggrno:25592Agrn; agrin77320.075% (1422/1884)Agrn2
smart00282smart00282, LamG, Laminin G domain;2922e-2740% (56/138)LamG1
smart200200smart00200, SEA, Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains2393e-2131% (39/125)SEA2
smart300180smart00180, EGF_Lam, Laminin-type epidermal growth factor-like domai;1408e-1039% (19/48)EGF_Lam3
smart400280smart00280, KAZAL, Kazal type serine protease inhibitors; Kazal type serine protease inhibitors and follistatin-like domains1749e-1445% (21/46)KAZAL4
pfamPF03146pfam03146, NtA, Agrin NtA domain6332e-6589% (111/124)NtA1
pfam2PF05760pfam05760, IER, Immediate early response protein (IER)1152e-0518% (31/167)IER10
pfam3PF00054pfam00054, Laminin_G, Laminin G domain3624e-3452% (72/136)Laminin_G2
pfam4PF01390pfam01390, SEA, SEA domain2641e-2233% (40/120)SEA3
pfam5PF00053pfam00053, Laminin_EGF, Laminin EGF-like (Domains III and V)1619e-1140% (20/49)Laminin_EGF4
pfam6PF03154pfam03154, Atrophin-1, Atrophin-1 family1521e-0926% (141/529)Atrophin-15
pfam7PF00050pfam00050, Kazal, Kazal-type serine protease inhibitor domain1538e-1050% (26/52)Kazal6