| smart9 | 00050 | smart00050, DISIN, Homologues of snake disintegrins ; Snake disintegrins inhibit the binding of ligands to integrin receptors | 96 | 1e-04 | 33% (19/57) | DISIN | | 9 | | |
| pfam8 | PF03157 | pfam03157, Glutenin_hmw, High molecular weight glutenin subunit | 136 | 7e-08 | 23% (96/402) | Glutenin_hmw | | 7 | | |
| pfam9 | PF03251 | pfam03251, Tymo_45kd_70kd, Tymovirus 45/70Kd protein | 111 | 6e-05 | 20% (87/416) | Tymo_45kd_70kd | | 8 | | |
| smart5 | 00181 | smart00181, EGF, Epidermal growth factor-like domain | 112 | 1e-06 | 45% (17/37) | EGF | | 5 | | |
| smart8 | 00157 | smart00157, PRP, Major prion protein; The prion protein is a major component of scrapie-associated fibrils in Creutzfeldt-Jakob disease, kuru, Gerstmann-Straussler syndrome and bovine spongiform encephalopathy | 99 | 4e-05 | 32% (34/105) | PRP | | 8 | | |
| pfam10 | PF05790 | pfam05790, CD2, T-cell surface antigen CD2 protein | 117 | 1e-05 | 36% (25/68) | CD2 | | 9 | | |
| smart6 | 00179 | smart00179, EGF_CA, Calcium-binding EGF-like domain; | 107 | 5e-06 | 47% (17/36) | EGF_CA | | 6 | | |
| smart7 | 00057 | smart00057, FIMAC, factor I membrane attack complex; | 102 | 2e-05 | 25% (16/64) | FIMAC | | 7 | | |
| Annotation Name | Agrin precursor related cluster |
| Score | 9830&emsp |
| E-value | 0.0 |
| % Sequence Identity | 90% (1820/2020) |
| Locus | Agrn |
| EC Number | |
| COG Function | |
| KEGG Pathway | |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_O00468 | Agrin precursor related cluster | 9830 | 0.0 | 90% (1820/2020) | | | 1 | | GO:0005198|structural molecule activity|IEA; GO:0005200|structural constituent of cytoskeleton|TAS; GO:0005509|calcium ion binding|IEA; GO:0005515|protein binding|IPI; GO:0005605|basal lamina|IDA; GO:0007155|cell adhesion|IEA; GO:0007165|signal transduction|TAS; GO:0007213|acetylcholine receptor signaling, muscarinic pathway|TAS; GO:0043113|receptor clustering|IDA; GO:0043113|receptor clustering|IMP; GO:0043236|laminin binding|TAS; GO:0045162|clustering of voltage-gated sodium channels|TAS; GO:0050808|synapse organization and biogenesis|TAS |
| nr | NP_786930 | agrin [Rattus norvegicus] gb|AAA40703.1| agrin | 7732 | 0.0 | 75% (1422/1888) | | | 4 | | |
| cog | YIR019c | | 133 | 1e-06 | 21% (138/629) | | | 0 | | |
| kegg | rno:25592 | Agrn; agrin | 7732 | 0.0 | 75% (1422/1884) | Agrn | | 2 | | |
| smart | 00282 | smart00282, LamG, Laminin G domain; | 292 | 2e-27 | 40% (56/138) | LamG | | 1 | | |
| smart2 | 00200 | smart00200, SEA, Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains | 239 | 3e-21 | 31% (39/125) | SEA | | 2 | | |
| smart3 | 00180 | smart00180, EGF_Lam, Laminin-type epidermal growth factor-like domai; | 140 | 8e-10 | 39% (19/48) | EGF_Lam | | 3 | | |
| smart4 | 00280 | smart00280, KAZAL, Kazal type serine protease inhibitors; Kazal type serine protease inhibitors and follistatin-like domains | 174 | 9e-14 | 45% (21/46) | KAZAL | | 4 | | |
| pfam | PF03146 | pfam03146, NtA, Agrin NtA domain | 633 | 2e-65 | 89% (111/124) | NtA | | 1 | | |
| pfam2 | PF05760 | pfam05760, IER, Immediate early response protein (IER) | 115 | 2e-05 | 18% (31/167) | IER | | 10 | | |
| pfam3 | PF00054 | pfam00054, Laminin_G, Laminin G domain | 362 | 4e-34 | 52% (72/136) | Laminin_G | | 2 | | |
| pfam4 | PF01390 | pfam01390, SEA, SEA domain | 264 | 1e-22 | 33% (40/120) | SEA | | 3 | | |
| pfam5 | PF00053 | pfam00053, Laminin_EGF, Laminin EGF-like (Domains III and V) | 161 | 9e-11 | 40% (20/49) | Laminin_EGF | | 4 | | |
| pfam6 | PF03154 | pfam03154, Atrophin-1, Atrophin-1 family | 152 | 1e-09 | 26% (141/529) | Atrophin-1 | | 5 | | |
| pfam7 | PF00050 | pfam00050, Kazal, Kazal-type serine protease inhibitor domain | 153 | 8e-10 | 50% (26/52) | Kazal | | 6 | | |