| Annotation Name | Protein-S-isoprenylcysteine O-methyltransferase related cluster |
| Score | 1303&emsp |
| E-value | 1e-143 |
| % Sequence Identity | 90% (246/273) |
| Locus | ICMT |
| EC Number | 2.1.1.100 |
| COG Function | Posttranslational modification, protein turnover, chaperones |
| KEGG Pathway | |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_O60725 | Protein-S-isoprenylcysteine O-methyltransferase related cluster | 1303 | 1e-143 | 90% (246/273) | ICMT | 2.1.1.100 | 1 | | GO:0003880|C-terminal protein carboxyl methyltransferase activity|TAS; GO:0004671|protein-S-isoprenylcysteine O-methyltransferase activity|IEA; GO:0005624|membrane fraction|TAS; GO:0005783|endoplasmic reticulum|IEA; GO:0005783|endoplasmic reticulum|TAS; GO:0006464|protein modification|TAS; GO:0006481|C-terminal protein amino acid methylation|IEA; GO:0006481|C-terminal protein amino acid methylation|TAS; GO:0006612|protein-membrane targeting|TAS; GO:0008168|methyltransferase activity|IEA; GO:0016021|integral to membrane|IEA; GO:0016740|transferase activity|IEA |
| nr | XP_546748 | PREDICTED: similar to Protein-S-isoprenylcysteine O-methyltransferase (Isoprenylcysteine carboxylmethyltransferase) (Prenylcysteine carboxyl methyltransferase) (pcCMT) (Prenylated protein carboxyl methyltransferase) (PPMT) [Canis familiaris] | 1270 | 1e-137 | 87% (238/273) | | | 2 | | |
| cog | YDR410c | [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase | 468 | 4e-46 | 42% (92/218) | | | 1 | Posttranslational modification, protein turnover, chaperones | |
| kegg | mmu:57295 | Icmt; isoprenylcysteine carboxyl methyltransferase [EC:2.1.1.100] | 1259 | 1e-138 | 86% (236/273) | Icmt | 2.1.1.100 | 2 | | |
| smart | | No hits found | | | | | | 0 | | |
| pfam | PF04140 | pfam04140, ICMT, Isoprenylcysteine carboxyl methyltransferase (ICMT) family | 323 | 8e-30 | 39% (38/96) | ICMT | | 1 | | |