Detailed annotation info for ENST00000323338; Methylenetetrahydrofolate reductase (EC 1.5.1.20). [Source:Uniprot/SWISSPROT;Acc:P42898]
| Annotation Name | Methylenetetrahydrofolate reductase related cluster | |||||||||
| Score | 3259&emsp | |||||||||
| E-value | 0.0 | |||||||||
| % Sequence Identity | 93% (612/656) | |||||||||
| Locus | MTHR | |||||||||
| EC Number | 1.5.1.20 | |||||||||
| COG Function | Amino acid transport and metabolism | |||||||||
| KEGG Pathway | One carbon pool by folate | |||||||||
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_P42898 | Methylenetetrahydrofolate reductase related cluster | 3259 | 0.0 | 93% (612/656) | MTHR | 1.5.1.20 | 1 | GO:0003824|catalytic activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|IEA; GO:0004489|methylenetetrahydrofolate reductase (NADPH) activity|TAS; GO:0006520|amino acid metabolism|TAS; GO:0006555|methionine metabolism|IEA; GO:0008015|circulation|TAS; GO:0016491|oxidoreductase activity|IEA | |
| nr | BAD51970 | 5,10-methylenetetrahydrofolate reductase [Macaca fascicularis] | 3215 | 0.0 | 91% (601/656) | 6 | ||||
| cog | SPAC56F8.10 | [E] COG0685 5,10-methylenetetrahydrofolate reductase | 1176 | 1e-129 | 42% (243/576) | 1 | Amino acid transport and metabolism | |||
| kegg | mmu:17769 | Mthfr; 5,10-methylenetetrahydrofolate reductase [EC:1.5.1.20] [KO:K00297] | 2951 | 0.0 | 84% (554/656) | Mthfr | 1.5.1.20 | 2 | One carbon pool by folate | |
| smart | No hits found | 0 | ||||||||
| pfam | PF02219 | pfam02219, MTHFR, Methylenetetrahydrofolate reductase | 1080 | 1e-117 | 55% (157/284) | MTHFR | 1 | |||