Detailed annotation info for ENST00000361947; FKBP-rapamycin associated protein (FRAP) (Rapamycin target protein). [Source:Uniprot/SWISSPROT;Acc:P42345]
| Annotation Name | FKBP12-rapamycin complex-associated protein related cluster | |||||||||
| Score | 12187&emsp | |||||||||
| E-value | 0.0 | |||||||||
| % Sequence Identity | 93% (2376/2551) | |||||||||
| Locus | Frap1 | |||||||||
| EC Number | ||||||||||
| COG Function | ||||||||||
| KEGG Pathway | ||||||||||
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_P42345 | FKBP12-rapamycin complex-associated protein related cluster | 12187 | 0.0 | 93% (2376/2551) | 1 | GO:0000074|regulation of cell cycle|TAS; GO:0004428|inositol or phosphatidylinositol kinase activity|NR; GO:0005488|binding|IEA; GO:0005942|phosphoinositide 3-kinase complex|NR; GO:0006281|DNA repair|NR; GO:0006310|DNA recombination|NR; GO:0016301|kinase activity|IEA; GO:0016740|transferase activity|IEA; GO:0016773|phosphotransferase activity, alcohol group as acceptor|IEA | |||
| nr | 2014422A | FKBP-rapamycin-associated protein | 12161 | 0.0 | 92% (2372/2551) | 2 | ||||
| cog | YKL203c | [TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family | 368 | 5e-34 | 38% (98/257) | 1 | ||||
| kegg | rno:56718 | Frap1; FK506 binding protein 12-rapamycin associated protein 1 | 12115 | 0.0 | 92% (2360/2551) | Frap1 | 2 | |||
| smart | 00146 | smart00146, PI3Kc, Phosphoinositide 3-kinase, catalytic domain; Phosphoinositide 3-kinase isoforms participate in a variety of processes, including cell motility, the Ras pathway, vesicle trafficking and secretion, and apoptosis | 753 | 8e-81 | 35% (106/301) | PI3Kc | 1 | |||
| smart2 | 00689 | smart00689, DM6, Cysteine-rich domain currently specific to Drosophila | 99 | 5e-05 | 26% (27/102) | DM6 | 2 | |||
| pfam | PF02259 | pfam02259, FAT, FAT domain | 1119 | 1e-122 | 31% (199/625) | FAT | 1 | |||
| pfam2 | PF00454 | pfam00454, PI3_PI4_kinase, Phosphatidylinositol 3- and 4-kinase | 608 | 2e-62 | 36% (91/251) | PI3_PI4_kinase | 2 | |||
| pfam3 | PF02260 | pfam02260, FATC, FATC domain | 154 | 7e-10 | 57% (19/33) | FATC | 3 | |||