| smart5 | 00109 | smart00109, C1, Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains); Some bind phorbol esters and diacylglycerol | 161 | 1e-12 | 39% (20/51) | C1 | | 5 | | |
| smart6 | 00750 | smart00750, KIND, kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe) | 103 | 6e-06 | 28% (31/110) | KIND | | 6 | | |
| Annotation Name | Protein kinase C, zeta type related cluster |
| Score | 3151&emsp |
| E-value | 0.0 |
| % Sequence Identity | 99% (589/590) |
| Locus | KPCZ |
| EC Number | 2.7.1.37 |
| COG Function | |
| KEGG Pathway | Calcium signaling pathway MAPK signaling pathway Phosphatidylinositol signaling system Wnt signaling pathway |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_Q05513 | Protein kinase C, zeta type related cluster | 3151 | 0.0 | 99% (589/590) | KPCZ | 2.7.1.37 | 1 | | GO:0004672|protein kinase activity|IEA; GO:0004672|protein kinase activity|TAS; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0004700|atypical protein kinase C activity|TAS; GO:0005524|ATP binding|IEA; GO:0005624|membrane fraction|TAS; GO:0005737|cytoplasm|TAS; GO:0005886|plasma membrane|TAS; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006468|protein amino acid phosphorylation|TAS; GO:0006916|anti-apoptosis|TAS; GO:0007165|signal transduction|TAS; GO:0007242|intracellular signaling cascade|IEA; GO:0016740|transferase activity|IEA; GO:0019992|diacylglycerol binding|IEA |
| nr | Q05513 | Protein kinase C, zeta type (nPKC-zeta) | 3151 | 0.0 | 99% (589/590) | | | 3 | | |
| cog | SPBC12D12.04c_2 | [RTKL] COG0515 Serine/threonine protein kinase | 771 | 7e-82 | 44% (148/334) | | | 1 | | |
| kegg | rno:25522 | Prkcz; protein kinase C, zeta [KO:K02677] | 3029 | 0.0 | 95% (566/590) | Prkcz | | 2 | Calcium signaling pathway MAPK signaling pathway Phosphatidylinositol signaling system Wnt signaling pathway | |
| smart | 00220 | smart00220, S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases | 714 | 8e-77 | 37% (102/270) | S_TKc | | 1 | | |
| smart2 | 00219 | smart00219, TyrKc, Tyrosine kinase, catalytic domain; Phosphotransferases | 302 | 5e-29 | 23% (60/254) | TyrKc | | 2 | | |
| smart3 | 00666 | smart00666, PB1, PB1 domain ; Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins | 206 | 7e-18 | 32% (27/83) | PB1 | | 3 | | |
| smart4 | 00133 | smart00133, S_TK_X, Extension to Ser/Thr-type protein kinases; | 195 | 1e-16 | 45% (29/64) | S_TK_X | | 4 | | |
| pfam | PF00069 | pfam00069, Pkinase, Protein kinase domain | 577 | 2e-59 | 33% (90/270) | Pkinase | | 1 | | |
| pfam2 | PF00433 | pfam00433, Pkinase_C, Protein kinase C terminal domain | 260 | 1e-22 | 50% (34/67) | Pkinase_C | | 2 | | |
| pfam3 | PF00130 | pfam00130, DAG_PE-bind, Phorbol esters/diacylglycerol binding domain (C1 domain) | 198 | 2e-15 | 48% (24/50) | DAG_PE-bind | | 3 | | |
| pfam4 | PF00564 | pfam00564, PB1, PB1 domain | 189 | 2e-14 | 35% (30/84) | PB1 | | 4 | | |