Annotation Name | Mannan-binding lectin serine protease 2 precursor related cluster |
Score | 960&emsp |
E-value | 1e-103 |
% Sequence Identity | 95% (173/181) |
Locus | Masp2 |
EC Number | |
COG Function | |
KEGG Pathway | Complement and coagulation cascades |
Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
uniref90 | UniRef90_O00187 | Mannan-binding lectin serine protease 2 precursor related cluster | 960 | 1e-103 | 95% (173/181) | | | 1 | | GO:0004252|serine-type endopeptidase activity|IEA; GO:0004252|serine-type endopeptidase activity|TAS; GO:0004263|chymotrypsin activity|IEA; GO:0004295|trypsin activity|IEA; GO:0005509|calcium ion binding|IEA; GO:0005576|extracellular region|IEA; GO:0006508|proteolysis and peptidolysis|IEA; GO:0006956|complement activation|IEA; GO:0006956|complement activation|TAS; GO:0006958|complement activation, classical pathway|IEA; GO:0008233|peptidase activity|IEA; GO:0008236|serine-type peptidase activity|TAS; GO:0016787|hydrolase activity|IEA; GO:0019735|antimicrobial humoral response (sensu Vertebrata)|TAS |
nr | 1SZB | Chain B, Crystal Structure Of The Human Mbl-Associated Protein 19 (Map19) pdb|1SZB|A Chain A, Crystal Structure Of The Human Mbl-Associated Protein 19 (Map19) | 948 | 1e-101 | 100% (170/170) | | | 8 | | |
cog | | No hits found | | | | | | 0 | | |
kegg | mmu:17175 | Masp2; mannan-binding lectin serine protease 2 [KO:K03993] | 777 | 2e-82 | 81% (137/168) | Masp2 | | 2 | Complement and coagulation cascades | |
smart | 00042 | smart00042, CUB, Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein | 249 | 2e-23 | 40% (46/113) | CUB | | 1 | | |
smart2 | 00179 | smart00179, EGF_CA, Calcium-binding EGF-like domain; | 105 | 1e-06 | 32% (15/46) | EGF_CA | | 2 | | |
smart3 | 00181 | smart00181, EGF, Epidermal growth factor-like domain | 89 | 8e-05 | 27% (10/37) | EGF | | 3 | | |
pfam | PF00431 | pfam00431, CUB, CUB domain | 198 | 5e-16 | 35% (39/111) | CUB | | 1 | | |
pfam2 | PF05955 | pfam05955, Herpes_gp2, Equine herpesvirus glycoprotein gp2 | 100 | 1e-04 | 23% (47/201) | Herpes_gp2 | | 2 | | |