Detailed annotation info for ENST00000340401; Rho guanine exchange factor 16; putative neuroblastoma protein [Homo sapiens]. [Source:RefSeq;Acc:NM_014448]
Annotation NameNeuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster
Score2004&emsp
E-value0.0
% Sequence Identity93% (393/421)
LocusArhgef16
EC Number
COG Function Signal transduction mechanisms
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90UniRef90_Q99434Neuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster20040.093% (393/421)1
nrCAH70832Rho guanine exchange factor (GEF) 16 [Homo sapiens]32910.091% (650/709)0
cogSPCC645.07[T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases2302e-1826% (70/265)1 Signal transduction mechanisms
keggmmu:230972Arhgef16; Rho guanine nucleotide exchange factor (GEF) 1625510.073% (518/709)Arhgef161
smart00325smart00325, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain4057e-4134% (62/182)RhoGEF1
smart200326smart00326, SH3, Src homology 3 domains; Src homology 3 (SH3) domains bind to target proteins through sequences containing proline and hydrophobic amino acids1216e-0833% (20/59)SH32
smart300233smart00233, PH, Pleckstrin homology domain931e-0422% (26/116)PH3
pfamPF00621pfam00621, RhoGEF, RhoGEF domain2582e-2228% (52/184)RhoGEF1
pfam2PF03157pfam03157, Glutenin_hmw, High molecular weight glutenin subunit1784e-1323% (144/616)Glutenin_hmw2
pfam3PF03154pfam03154, Atrophin-1, Atrophin-1 family1301e-0723% (152/656)Atrophin-13
pfam4PF00169pfam00169, PH, PH domain1184e-0626% (31/119)PH4
pfam5PF03251pfam03251, Tymo_45kd_70kd, Tymovirus 45/70Kd protein1122e-0526% (39/149)Tymo_45kd_70kd5
pfam6PF05760pfam05760, IER, Immediate early response protein (IER)1122e-0524% (56/228)IER6
pfam7PF07223pfam07223, DUF1421, Protein of unknown function (DUF1421)1122e-0523% (60/252)DUF14217