Annotation Name | Neuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster |
Score | 2004&emsp |
E-value | 0.0 |
% Sequence Identity | 93% (393/421) |
Locus | Arhgef16 |
EC Number | |
COG Function | Signal transduction mechanisms |
KEGG Pathway | |
Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
uniref90 | UniRef90_Q99434 | Neuroblastoma (Rho guanine exchange factor (GEF) 16) related cluster | 2004 | 0.0 | 93% (393/421) | | | 1 | | |
nr | CAH70832 | Rho guanine exchange factor (GEF) 16 [Homo sapiens] | 3291 | 0.0 | 91% (650/709) | | | 0 | | |
cog | SPCC645.07 | [T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases | 230 | 2e-18 | 26% (70/265) | | | 1 | Signal transduction mechanisms | |
kegg | mmu:230972 | Arhgef16; Rho guanine nucleotide exchange factor (GEF) 16 | 2551 | 0.0 | 73% (518/709) | Arhgef16 | | 1 | | |
smart | 00325 | smart00325, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain | 405 | 7e-41 | 34% (62/182) | RhoGEF | | 1 | | |
smart2 | 00326 | smart00326, SH3, Src homology 3 domains; Src homology 3 (SH3) domains bind to target proteins through sequences containing proline and hydrophobic amino acids | 121 | 6e-08 | 33% (20/59) | SH3 | | 2 | | |
smart3 | 00233 | smart00233, PH, Pleckstrin homology domain | 93 | 1e-04 | 22% (26/116) | PH | | 3 | | |
pfam | PF00621 | pfam00621, RhoGEF, RhoGEF domain | 258 | 2e-22 | 28% (52/184) | RhoGEF | | 1 | | |
pfam2 | PF03157 | pfam03157, Glutenin_hmw, High molecular weight glutenin subunit | 178 | 4e-13 | 23% (144/616) | Glutenin_hmw | | 2 | | |
pfam3 | PF03154 | pfam03154, Atrophin-1, Atrophin-1 family | 130 | 1e-07 | 23% (152/656) | Atrophin-1 | | 3 | | |
pfam4 | PF00169 | pfam00169, PH, PH domain | 118 | 4e-06 | 26% (31/119) | PH | | 4 | | |
pfam5 | PF03251 | pfam03251, Tymo_45kd_70kd, Tymovirus 45/70Kd protein | 112 | 2e-05 | 26% (39/149) | Tymo_45kd_70kd | | 5 | | |
pfam6 | PF05760 | pfam05760, IER, Immediate early response protein (IER) | 112 | 2e-05 | 24% (56/228) | IER | | 6 | | |
pfam7 | PF07223 | pfam07223, DUF1421, Protein of unknown function (DUF1421) | 112 | 2e-05 | 23% (60/252) | DUF1421 | | 7 | | |