| Annotation Name | DNA topoisomerase II related cluster |
| Score | 6025&emsp |
| E-value | 0.0 |
| % Sequence Identity | 85% (1185/1388) |
| Locus | TOP2 |
| EC Number | 5.99.1.3 |
| COG Function | Replication, recombination and repair |
| KEGG Pathway | |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_P41001 | DNA topoisomerase II related cluster | 6025 | 0.0 | 85% (1185/1388) | TOP2 | 5.99.1.3 | 1 | | GO:0003677|DNA binding|IEA; GO:0003916|DNA topoisomerase activity|IEA; GO:0003918|DNA topoisomerase (ATP-hydrolyzing) activity|IEA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0006259|DNA metabolism|IEA; GO:0006265|DNA topological change|IEA; GO:0016853|isomerase activity|IEA |
| nr | P41001 | DNA TOPOISOMERASE II | 6025 | 0.0 | 85% (1185/1389) | | | 3 | | |
| cog | YNL088w_1 | [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit | 1506 | 1e-168 | 45% (321/708) | | | 1 | Replication, recombination and repair | |
| kegg | ath:At3g23890 | F14O13.32; DNA topoisomerase, ATP-hydrolyzing / DNA topoisomerase II / DNA gyrase (TOP2) [EC:5.99.1.3] [KO:K03164] | 2757 | 0.0 | 47% (585/1219) | | 5.99.1.3 | 2 | | |
| smart | 00433 | smart00433, TOP2c, TopoisomeraseII; Eukaryotic DNA topoisomerase II, GyrB, ParE | 1777 | 0.0 | 34% (229/666) | TOP2c | | 1 | | |
| smart2 | 00434 | smart00434, TOP4c, DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC | 1239 | 1e-137 | 34% (169/493) | TOP4c | | 2 | | |
| pfam | PF00521 | pfam00521, DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A | 1103 | 1e-120 | 28% (136/475) | DNA_topoisoIV | | 1 | | |
| pfam2 | PF00204 | pfam00204, DNA_gyraseB, DNA gyrase B | 390 | 2e-37 | 31% (51/163) | DNA_gyraseB | | 2 | | |
| pfam3 | PF04922 | pfam04922, DIE2_ALG10, DIE2/ALG10 family | 122 | 2e-06 | 23% (59/250) | DIE2_ALG10 | | 3 | | |
| pfam4 | PF04165 | pfam04165, DUF401, Protein of unknown function (DUF401) | 113 | 2e-05 | 22% (53/236) | DUF401 | | 4 | | |
| pfam5 | PF05296 | pfam05296, TAS2R, Mammalian taste receptor protein (TAS2R) | 112 | 3e-05 | 20% (54/267) | TAS2R | | 5 | | |
| pfam6 | PF05557 | pfam05557, MAD, Mitotic checkpoint protein | 110 | 5e-05 | 20% (97/466) | MAD | | 6 | | |
| pfam7 | PF00361 | pfam00361, Oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains | 109 | 6e-05 | 21% (53/252) | Oxidored_q1 | | 7 | | |