Reverse gyrase from hyperthermophiles:
probable transfer of a thermo-adaptation trait from Archaea to Bacteria

Forterre P., Bouthier de la Tour C., Philippe H., Duguet M.
Trends Genet. 2000 Apr;16(4):152-4




Phylogenetic analysis:

The files of aligned sequences that have been used in this study can be downloaded here in PHYLIP format (don't forget to hold down SHIFT while clicking on the link):

Reverse gyrase data set, complete
Reverse gyrase data set, positions selected by G-Blocks
(version 0.73b, Jose Castresana, 1999)
Reverse gyrase data set, positions actually used for this study
Topo-isomerase I (+ reverse gyrase) data set, complete
Topo-isomerase I (+ reverse gyrase) data set, positions actually used for this study
The corresponding trees are also available:
Reverse gyrase data set, positions selected by G-Blocks
Reverse gyrase data set, positions actually used for this study
Topo-isomerase I (+ reverse gyrase) data set, positions actually used for this study
Mutational saturation plots:
Reverse gyrase, G-Blocks 
Reverse gyrase, this study 
Topo-isomerase I, this study 

BLAST searchs on the vicinity of the reverse gyrase gene:
Click on a gene to see the corresponding BLAST search. Genes with a bacterial  homologue as first hit are displayed in green, genes with an archeal one are displayed in red and others are displayed in white.


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Reverse Gyrase 1-6Reverse Gyrase 1 -5Reverse Gyrase 1 -4Reverse Gyrase 1 -3Reverse Gyrase 1 -2Reverse Gyrase 1 -1Reverse Gyrase 1 +1Reverse Gyrase 1 +2Reverse Gyrase 1 +3Reverse Gyrase 1 +4Reverse Gyrase 1 +5Reverse Gyrase 1 +6Reverse Gyrase 1 +7Reverse Gyrase 1 +8Reverse Gyrase 1 +9Reverse Gyrase 2 -5Reverse Gyrase 2 -4Reverse Gyrase 2 -3Reverse Gyrase 2 -2Reverse Gyrase 2 -1Reverse Gyrase 2 +1Reverse Gyrase 2 +2Reverse Gyrase 2 +3Reverse Gyrase 2 +4Reverse Gyrase 2 +5Reverse Gyrase 2 +6Reverse Gyrase -5Reverse Gyrase -4Reverse Gyrase -3Reverse Gyrase -2Reverse Gyrase -1Reverse Gyrase +1Reverse Gyrase +2Reverse Gyrase +3Reverse Gyrase +4Reverse Gyrase +5