Detailed annotation info for ACL00009150;
Annotation NameSon of sevenless protein homolog 1 related cluster
Score321&emsp
E-value4e-29
% Sequence Identity36% (64/176)
LocusSOS1
EC Number
COG Function
KEGG Pathway Integrin-mediated cell adhesion Jak-STAT signaling pathway MAPK signaling pathway Regulation of actin cytoskeleton
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
SSUNo hits found0
LSUNo hits found0
uniref90UniRef90_Q07889Son of sevenless protein homolog 1 related cluster3214e-2936% (64/176)1GO:0003677|DNA binding|IEA; GO:0005085|guanyl-nucleotide exchange factor activity|IEA; GO:0005088|Ras guanyl-nucleotide exchange factor activity|TAS; GO:0005089|Rho guanyl-nucleotide exchange factor activity|TAS; GO:0005100|Rho GTPase activator activity|TAS; GO:0007165|signal transduction|NAS; GO:0007242|intracellular signaling cascade|IEA; GO:0007264|small GTPase mediated signal transduction|IEA; GO:0007265|Ras protein signal transduction|TAS
nrXP_423646PREDICTED: similar to son of sevenless homolog 1; gingival fibromatosis, hereditary, 1; gingival fibromatosis [Gallus gallus]3263e-2937% (66/176)1
cogSPBC336.032403e-2030% (54/179)0
kegghsa:6654SOS1; son of sevenless homolog 1 (Drosophila) [KO:K03099]3214e-2936% (64/176)SOS11 Integrin-mediated cell adhesion Jak-STAT signaling pathway MAPK signaling pathway Regulation of actin cytoskeleton
smart00147smart00147, RasGEF, Guanine nucleotide exchange factor for Ras-like small GTPases;4321e-4441% (75/181)RasGEF1
smart200689smart00689, DM6, Cysteine-rich domain currently specific to Drosophila1085e-0727% (33/118)DM62
pfamPF00617pfam00617, RasGEF, RasGEF domain3392e-3239% (63/159)RasGEF1
est_othersCA380597659921 NCCCWA 1RT Oncorhynchus mykiss cDNA clone 1RT50P13_B_H07 5'.1249e-3233% (25/75)1