Detailed annotation info for ACL00009150;
| Annotation Name | Son of sevenless protein homolog 1 related cluster | |||||||||
| Score | 321&emsp | |||||||||
| E-value | 4e-29 | |||||||||
| % Sequence Identity | 36% (64/176) | |||||||||
| Locus | SOS1 | |||||||||
| EC Number | ||||||||||
| COG Function | ||||||||||
| KEGG Pathway | Integrin-mediated cell adhesion Jak-STAT signaling pathway MAPK signaling pathway Regulation of actin cytoskeleton | |||||||||
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| SSU | No hits found | 0 | ||||||||
| LSU | No hits found | 0 | ||||||||
| uniref90 | UniRef90_Q07889 | Son of sevenless protein homolog 1 related cluster | 321 | 4e-29 | 36% (64/176) | 1 | GO:0003677|DNA binding|IEA; GO:0005085|guanyl-nucleotide exchange factor activity|IEA; GO:0005088|Ras guanyl-nucleotide exchange factor activity|TAS; GO:0005089|Rho guanyl-nucleotide exchange factor activity|TAS; GO:0005100|Rho GTPase activator activity|TAS; GO:0007165|signal transduction|NAS; GO:0007242|intracellular signaling cascade|IEA; GO:0007264|small GTPase mediated signal transduction|IEA; GO:0007265|Ras protein signal transduction|TAS | |||
| nr | XP_423646 | PREDICTED: similar to son of sevenless homolog 1; gingival fibromatosis, hereditary, 1; gingival fibromatosis [Gallus gallus] | 326 | 3e-29 | 37% (66/176) | 1 | ||||
| cog | SPBC336.03 | 240 | 3e-20 | 30% (54/179) | 0 | |||||
| kegg | hsa:6654 | SOS1; son of sevenless homolog 1 (Drosophila) [KO:K03099] | 321 | 4e-29 | 36% (64/176) | SOS1 | 1 | Integrin-mediated cell adhesion Jak-STAT signaling pathway MAPK signaling pathway Regulation of actin cytoskeleton | ||
| smart | 00147 | smart00147, RasGEF, Guanine nucleotide exchange factor for Ras-like small GTPases; | 432 | 1e-44 | 41% (75/181) | RasGEF | 1 | |||
| smart2 | 00689 | smart00689, DM6, Cysteine-rich domain currently specific to Drosophila | 108 | 5e-07 | 27% (33/118) | DM6 | 2 | |||
| pfam | PF00617 | pfam00617, RasGEF, RasGEF domain | 339 | 2e-32 | 39% (63/159) | RasGEF | 1 | |||
| est_others | CA380597 | 659921 NCCCWA 1RT Oncorhynchus mykiss cDNA clone 1RT50P13_B_H07 5'. | 124 | 9e-32 | 33% (25/75) | 1 | ||||