Detailed annotation info for ACL00002858;
Annotation NameSerine/threonine-protein kinase 3 related cluster
Score259&emsp
E-value1e-21
% Sequence Identity56% (51/91)
LocusSTK3
EC Number2.7.1.37
COG Function
KEGG Pathway MAPK signaling pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
SSUNo hits found0
LSUNo hits found0
uniref90UniRef90_Q13188Serine/threonine-protein kinase 3 related cluster2591e-2156% (51/91)STK32.7.1.371GO:0000287|magnesium ion binding|IDA; GO:0000287|magnesium ion binding|IEA; GO:0004672|protein kinase activity|IEA; GO:0004672|protein kinase activity|TAS; GO:0004674|protein serine/threonine kinase activity|IDA; GO:0004674|protein serine/threonine kinase activity|IEA; GO:0004713|protein-tyrosine kinase activity|IEA; GO:0005515|protein binding|IEA; GO:0005524|ATP binding|IDA; GO:0005524|ATP binding|IEA; GO:0005634|nucleus|IEA; GO:0005737|cytoplasm|NR; GO:0006468|protein amino acid phosphorylation|IDA; GO:0006468|protein amino acid phosphorylation|IEA; GO:0006915|apoptosis|IEA; GO:0006915|apoptosis|NR; GO:0007165|signal transduction|IEA; GO:0007165|signal transduction|TAS; GO:0007243|protein kinase cascade|IDA; GO:0016740|transferase activity|IEA; GO:0043065|positive regulation of apoptosis|ISS; GO:0046983|protein dimerization activity|ISS
nrQ13188Serine/threonine-protein kinase 3 (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) gb|AAB17261.1| serine/threonine protein kinase Krs-1 [Homo sapiens] gb|AAH10640.1| Serine/threonine kinase 3 (STE20 homolog, yeast) [Homo sapiens]2593e-2156% (51/91)2
cogSPAC2C4.14c[RTKL] COG0515 Serine/threonine protein kinase1922e-1449% (41/83)1
kegghsa:6788STK3; serine/threonine kinase 3 (STE20 homolog, yeast) [EC:2.7.1.37] [KO:K04412]2591e-2156% (51/91)STK32.7.1.371 MAPK signaling pathway
smart00220smart00220, S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases1973e-1737% (28/75)S_TKc1
smart200750smart00750, KIND, kinase non-catalytic C-lobe domain; It is an interaction domain identified as being similar to the C-terminal protein kinase catalytic fold (C lobe)1472e-1128% (26/91)KIND2
smart300219smart00219, TyrKc, Tyrosine kinase, catalytic domain; Phosphotransferases971e-0525% (18/71)TyrKc3
pfamPF00069pfam00069, Pkinase, Protein kinase domain1951e-1534% (26/76)Pkinase1
est_othersBJ346427BJ346427 Dictyostelium discoideum cDNA library, AF Dictyostelium discoideum cDNA clone dda30j22 3'.1241e-1152% (27/51)1