Detailed annotation info for ACL00001004;
Annotation NamePeroxisomal multifunctional enzyme type 2 related cluster
Score436&emsp
E-value2e-42
% Sequence Identity46% (90/194)
LocusDHB4
EC Number1.1.1.35
COG Function
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
SSUNo hits found0
LSUNo hits found0
uniref90UniRef90_P51659Peroxisomal multifunctional enzyme type 2 related cluster4362e-4246% (90/194)DHB41.1.1.352GO:0003824|catalytic activity|IEA; GO:0003857|3-hydroxyacyl-CoA dehydrogenase activity|IEA; GO:0004303|estradiol 17-beta-dehydrogenase activity|TAS; GO:0005498|sterol carrier activity|IEA; GO:0005498|sterol carrier activity|TAS; GO:0005777|peroxisome|IEA; GO:0005777|peroxisome|TAS; GO:0006631|fatty acid metabolism|IEA; GO:0008152|metabolism|IEA; GO:0015248|sterol transporter activity|TAS; GO:0016491|oxidoreductase activity|IEA; GO:0016829|lyase activity|IEA; GO:0016853|isomerase activity|IEA
nrNP_000405hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens] sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase ; 3-hydroxyacyl-CoA dehydrogenase ] pir||S59136 estradiol 17beta-dehydrogenase (EC 1.1.1.62) type 4 - human emb|CAA60643.1| 17beta-hydroxysteroid dehydrogenase [Homo sapiens] gb|AAD08652.1| 17-beta-hydroxysteroid dehydrogenase IV [Homo sapiens] gb|AAH03098.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]4365e-4246% (90/194)2
cogPA1018[I] COG2030 Acyl dehydratase2611e-2244% (62/138)1 Lipid transport and metabolism
kegghsa:3295HSD17B4; hydroxysteroid (17-beta) dehydrogenase 4 [EC:1.1.1.62] [KO:K00044]4362e-4246% (90/194)HSD17B41.1.1.621 Androgen and estrogen metabolism
smartNo hits found0
pfamPF01575pfam01575, MaoC_dehydratas, MaoC like domain2746e-2531% (38/120)MaoC_dehydratas1
est_othersCF110396Shultzomica03647 Rat lung airway and parenchyma cDNA libraries Rattus norvegicus cDNA clone Contig3227 5'.2036e-1854% (49/90)1