Detailed annotation info for yhr111w; "UBA4 - conjugation system, E1-like protein"
Annotation NameUBA4; ubiquitin (URM1) activating enzyme [EC:6.3.2.19]
Score1165&emsp
E-value1e-126
% Sequence Identity51% (229/448)
LocusUBA4
EC Number6.3.2.19
COG Function Coenzyme transport and metabolism
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90UniRef90_O59954Molybdenum cofactor biosynthetic protein related cluster8643e-9142% (197/464)8GO:0003824|catalytic activity|IEA
nrNP_011979Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response [Saccharomyces cerevisiae] sp|P38820|YHR1_YEAST Hypothetical 49.4 kDa protein in CDC12-ORC6 intergenic region gb|AAB68852.1| Yhr111wp [Saccharomyces cerevisiae] pir||S48953 hypothetical protein YHR111w - yeast (Saccharomyces cerevisiae)23160.0100% (440/440)0
cogYHR111w_1[H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 215371e-170100% (293/293)1 Coenzyme transport and metabolism
keggcal:orf19.2324UBA4; ubiquitin (URM1) activating enzyme [EC:6.3.2.19]11651e-12651% (229/448)UBA46.3.2.193
smart00450smart00450, RHOD, Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein1983e-1734% (36/105)RHOD1
pfamPF00899pfam00899, ThiF, ThiF family4041e-3944% (60/136)ThiF1
pfam2PF05237pfam05237, MoeZ_MoeB, MoeZ/MoeB domain2338e-2039% (34/86)MoeZ_MoeB2
pfam3PF00581pfam00581, Rhodanese, Rhodanese-like domain1872e-1433% (36/109)Rhodanese3