| Annotation Name | Polymyositis/scleroderma autoantigen 2 related cluster |
| Score | 4369&emsp |
| E-value | 0.0 |
| % Sequence Identity | 95% (844/885) |
| Locus | |
| EC Number | |
| COG Function | |
| KEGG Pathway | |
| Source | Accession | Description | Score | E-value | % Sequence Identity | Locus | EC Number | Informative Hit | Function/Pathway | GeneOntology |
| uniref90 | UniRef90_Q01780 | Polymyositis/scleroderma autoantigen 2 related cluster | 4369 | 0.0 | 95% (844/885) | | | 1 | | GO:0003676|nucleic acid binding|IEA; GO:0003723|RNA binding|IEA; GO:0004518|nuclease activity|IEA; GO:0004527|exonuclease activity|IEA; GO:0004674|protein serine/threonine kinase activity|TAS; GO:0005622|intracellular|IEA; GO:0005634|nucleus|IEA; GO:0005730|nucleolus|TAS; GO:0006364|rRNA processing|IEA; GO:0008408|3'-5' exonuclease activity|IEA; GO:0016787|hydrolase activity|IEA |
| nr | NP_057908 | exosome component 10 [Mus musculus] gb|AAF01779.1| P100 polymyositis-scleroderma overlap syndrome associated autoantigen homolog [Mus musculus] sp|P56960|PMC2_MOUSE Polymyositis/scleroderma autoantigen 100 kDa (Exosome component 10) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome associated autoantigen homolog) | 3849 | 0.0 | 83% (741/887) | | | 3 | | |
| cog | YOR001w_2 | [J] COG0349 Ribonuclease D | 598 | 2e-61 | 41% (130/310) | | | 1 | Translation, ribosomal structure and biogenesis | |
| kegg | mmu:50912 | Exosc10; exosome component 10 | 3849 | 0.0 | 83% (741/885) | Exosc10 | | 2 | | |
| smart | 00474 | smart00474, 35EXOc, 3'-5' exonuclease; 3\' -5' exonuclease proofreading domain present in DNA polymerase I, Werner syndrome helicase, RNase D and other enzymes | 397 | 6e-40 | 40% (69/171) | 35EXOc | | 1 | | |
| smart2 | 00341 | smart00341, HRDC, Helicase and RNase D C-terminal; Hypothetical role in nucleic acid binding | 209 | 3e-18 | 30% (25/81) | HRDC | | 2 | | |
| pfam | PF01612 | pfam01612, 3_5_exonuc, 3'-5' exonuclease | 511 | 1e-51 | 45% (78/172) | 3_5_exonuc | | 1 | | |
| pfam2 | PF00570 | pfam00570, HRDC, HRDC domain | 232 | 2e-19 | 35% (29/81) | HRDC | | 2 | | |