Detailed annotation info for ENST00000270747; Rho guanine nucleotide exchange factor (GEF) 19 [Homo sapiens]. [Source:RefSeq;Acc:NM_153213]
Annotation NameArhgef19; Rho guanine nucleotide exchange factor (GEF) 19
Score3151&emsp
E-value0.0
% Sequence Identity79% (634/801)
LocusArhgef19
EC Number
COG Function Signal transduction mechanisms
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
uniref90
nrXP_524519PREDICTED: similar to Rho guanine nucleotide exchange factor (GEF) 19 [Pan troglodytes]35140.086% (699/804)2
cogSPCC645.07[T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases2016e-1523% (72/308)1 Signal transduction mechanisms
keggmmu:213649Arhgef19; Rho guanine nucleotide exchange factor (GEF) 1931510.079% (634/801)Arhgef192
smart00325smart00325, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain3511e-3431% (56/180)RhoGEF1
smart200326smart00326, SH3, Src homology 3 domains; Src homology 3 (SH3) domains bind to target proteins through sequences containing proline and hydrophobic amino acids1404e-1045% (27/59)SH32
smart300233smart00233, PH, Pleckstrin homology domain948e-0521% (23/109)PH3
pfamPF00621pfam00621, RhoGEF, RhoGEF domain2279e-1927% (51/183)RhoGEF1
pfam2PF00018pfam00018, SH3, SH3 domain1184e-0642% (21/49)SH32