Score E
Sequences producing significant alignments: (bits) Value
gi|2983615 (AE000726) ferredoxin oxidoreductase alpha subun... 751 0.0
gi|2983644 (AE000728) ferredoxin oxidoreductase alpha subun... 397 e-109
gi|2648853 (AE000986) pyruvate ferredoxin oxidoreductase, s... 153 2e-36
sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVA... 150 2e-35
gi|2648476 (AE000961) 2-ketoisovalerate ferredoxin oxidored... 134 2e-30
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVA... 133 2e-30
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVA... 124 1e-27
emb|CAA59457| (X85171) alpha subunit of pyruvate ferredoxin... 124 1e-27
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVA... 122 4e-27
emb|CAB50271.1| (AJ248287) KETOISOVALERATE OXIDOREDUCTASE S... 116 2e-25
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT... 116 3e-25
dbj|BAA29771| (AP000003) 397aa long hypothetical ferredoxin... 116 3e-25
gi|2853363 (AF013980) pyruvate:ferredoxin oxidoreductase al... 114 1e-24
gi|4155626 (AE001531) Pyruvate ferrodoxin oxidoreductase [H... 114 2e-24
gb|AAD08154.1| (AE000617) pyruvate ferredoxin oxidoreductas... 114 2e-24
emb|CAA69455| (Y08256) pyruvate-ferredoxin oxidoreductase a... 111 8e-24
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT... 110 2e-23
emb|CAB50268.1| (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (... 109 3e-23
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVA... 108 1e-22
dbj|BAA29775| (AP000003) 398aa long hypothetical ferredoxin... 108 1e-22
gi|2935172 (AF021092) PorA subunit of pyruvate:flavodoxin o... 87 2e-16
dbj|BAA30778| (AP000006) 408aa long hypothetical ferredoxin... 86 5e-16
emb|CAB49426.1| (AJ248284) 2-ketoglutarate ferredoxin oxido... 83 5e-15
gi|3746570 (AF061850) putative pyruvate oxidoreductase; POR... 82 8e-15
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT... 74 2e-12
gi|2621790 (AE000849) 2-oxoisovalerate oxidoreductase, beta... 73 3e-12
dbj|BAA30774| (AP000006) 385aa long hypothetical ferredoxin... 72 7e-12
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (... 69 6e-11
gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxi... 68 1e-10
sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (... 68 1e-10
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (... 67 3e-10
gi|2622136 (AE000875) 2-oxoglutarate oxidoreductase, alpha ... 67 3e-10
emb|CAB49429.1| (AJ248284) 2-ketoglutarate ferredoxin oxido... 66 4e-10
sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi... 63 3e-09
sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDU... 62 6e-09
emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase... 59 5e-08
pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxi... 59 5e-08
emb|CAA70873| (Y09702) pyruvate-ferredoxin oxidoreductase [... 59 5e-08
gb|AAD35959.1|AE001753_15 (AE001753) pyruvate:ferredoxin 2-... 59 9e-08
sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDU... 59 9e-08
gi|1888325 (U30149) pyruvate:ferredoxin oxidoreductase [Ent... 58 2e-07
gi|960283 (L27221) pyruvate:ferredoxin oxidoreductase [Giar... 58 2e-07
gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferre... 57 2e-07
gb|AAD36824.1|AE001814_6 (AE001814) 2-oxoisovalerate oxidor... 56 6e-07
gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxi... 55 1e-06
emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase... 54 2e-06
sp|O27880|IORA_METTH INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT ... 54 2e-06
emb|CAA16032| (AL021246) hypothetical protein Rv2455c [Myco... 53 4e-06
sp|O28783|IORA_ARCFU INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT ... 49 6e-05
pir||S58236 pyruvate oxidoreductase - Entamoeba histolytica... 49 6e-05
dbj|BAA80471.1| (AP000061) 616aa long hypothetical 2-oxoaci... 49 8e-05
sp|O07835|IORA_PYRKO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT ... 48 1e-04
sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi... 48 1e-04
emb|CAA57480| (X81893) nifJ [Enterobacter agglomerans] 48 1e-04
sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi... 47 2e-04
pir||QQKBFP pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.... 44 0.002
sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi... 44 0.002
emb|CAB50202.1| (AJ248287) indolepyruvate ferredoxin oxidor... 44 0.003
gi|3323259 (AE001262) pyruvate oxidoreductase [Treponema pa... 44 0.003
dbj|BAA79551.1| (AP000060) 322aa long hypothetical transket... 43 0.006
dbj|BAA30238| (AP000005) 618aa long hypothetical indolepyru... 41 0.017
sp|O58495|IORA_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT ... 41 0.022
dbj|BAA81137.1| (AP000063) 644aa long hypothetical 2-oxoaci... 40 0.029
gi|622960 (U16823) pyruvate:ferredoxin oxidoreductase propr... 39 0.049
gi|4155084 (AE001486) SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCT... 39 0.085
gi|2935179 (AF021094) OorA subunit of 2-oxoglutarate:accept... 38 0.15
gb|AAD07654.1| (AE000572) ferredoxin oxidoreductase, alpha ... 38 0.15
sp|P55573|Y4MN_RHISN HYPOTHETICAL TRANSKETOLASE FAMILY PROT... 38 0.15
gi|622958 (U16822) pyruvate:ferredoxin oxidoreductas propro... 38 0.19
pir||A54346 pyruvate synthase (EC 1.2.7.1) alpha subunit - ... 36 0.43
gi|2338700 (AF013755) pyruvate dehydrogenase testis-specifi... 36 0.56
emb|CAA34396| (X16345) nifJ [Klebsiella pneumoniae] 35 0.96
emb|CAB60189.1| (AL132824) putative oxidoreductase alpha-su... 35 1.3
gb|AAD28766.1| (AF132216) 2-oxoisovalerate oxidoreductase b... 34 2.2
pir||I40791 TPP-dependent acetoin dehydrogenase beta chain ... 34 2.2
gi|2649863 (AE001053) 2-oxoacid ferredoxin oxidoreductase, ... 34 2.8
sp|P26242|DXS_RHOCA PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SY... 34 2.8
gb|AAF04897.1|AC011437_12 (AC011437) unknown protein [Arabi... 33 3.7
emb|CAA85315.1| (Z36719) weak similarity to E. coli LON ATP... 33 3.7
pir||S49915 extensin-like protein - maize >gi|600118|emb|CA... 32 6.4
gi|4204270 (AC005223) branched-chain alpha-keto acid decarb... 32 8.3
gi|3746568 (AF061638) branched-chain alpha-keto acid decarb... 32 8.3
gi|551853 (M26931) oxido-reductase (nifJ) [Enterobacter agg... 32 8.3
gi|2983615 (AE000726) ferredoxin oxidoreductase alpha subunit [Aquifex
aeolicus]
Length = 389
Score = 751 bits (1919), Expect = 0.0
Identities = 373/389 (95%), Positives = 373/389 (95%)
Query: 1 MPEQRVVEPDYLLLEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLY 60
MPEQRVVEPDYLLLEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLY
Sbjct: 1 MPEQRVVEPDYLLLEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLY 60
Query: 61 AQGYVKDYYRAEEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLG 120
AQGYVKDYYRAEEEYGAMS SGPGLLRGLEAIVSWPGHRIPAVLG
Sbjct: 61 AQGYVKDYYRAEEEYGAMSAIAGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLG 120
Query: 121 VMTRVVNAPLSIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVV 180
VMTRVVNAPLSIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVV
Sbjct: 121 VMTRVVNAPLSIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVV 180
Query: 181 ATEGFFVTHAKGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYL 240
ATEGFFVTHAKGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYL
Sbjct: 181 ATEGFFVTHAKGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYL 240
Query: 241 IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG 300
IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG
Sbjct: 241 IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG 300
Query: 301 LNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRV 360
LNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRV
Sbjct: 301 LNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRV 360
Query: 361 YGGMTLPVELIMEEIYKAFGIKKEKKVVV 389
YGGMTLPVELIMEEIYKAFGIKKEKKVVV
Sbjct: 361 YGGMTLPVELIMEEIYKAFGIKKEKKVVV 389
gi|2983644 (AE000728) ferredoxin oxidoreductase alpha subunit [Aquifex
aeolicus]
Length = 404
Score = 397 bits (1008), Expect = e-109
Identities = 196/389 (50%), Positives = 269/389 (68%), Gaps = 6/389 (1%)
Query: 4 QRVVEPDYLLLEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQG 63
QR+V PDYLL EAPR K FITGS+A EA KRA+VD +I+YPITPQSE H++G+L+ +G
Sbjct: 17 QRIVSPDYLLFEAPRTKHFITGSEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREG 76
Query: 64 YVKDYYRAEEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMT 123
Y+ Y+R E E+G MS SGPG +R +E W G R+P L +M
Sbjct: 77 YIGVYFRGESEFGVMSEVAGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMA 136
Query: 124 RVVNAPLSIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATE 183
R +N+PLSIQPDN+EIS+LL++G +V HAE Q++FD +AGFV++E+ DV++P++ A +
Sbjct: 137 RGINSPLSIQPDNLEISFLLDTGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAID 196
Query: 184 GFFVTHAKGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHA 243
GFF++H + V LPPED+ LPP +PYKAP+PP D E+PP R RD V KSN++SY HA
Sbjct: 197 GFFISHTREAVYLPPEDIALPPYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYATHA 256
Query: 244 VWQQEVWSANRRAAKWIKHYLGGLIE-VVNPDAEVFVVASGCAAAQGREA-QRYATMEGL 301
WQ EV +A R+ + KHYL GL+E +P+ EV +ASG AAAQ +EA Q EG+
Sbjct: 257 SWQFEVRAAIERSRPYAKHYLRGLVEHFGDPEGEVLFIASGTAAAQAKEATQILIHEEGI 316
Query: 302 NVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPN-SGIVVDG-PR 359
++++K+LRPFP +E+REA+K AK + +PE N+VGWL +EVK A+ + I + G PR
Sbjct: 317 KARVLRLKTLRPFPTEEVREAVKGAKYIFIPEFNVVGWLEREVKRALYGYTDIPIFGTPR 376
Query: 360 VYGGMTLPVELIMEEIYKAFGIKKEKKVV 388
V GGMT+P E I++E+ + G KE K V
Sbjct: 377 VGGGMTMPPEFIVQEVLRLIG--KEVKHV 403
gi|2648853 (AE000986) pyruvate ferredoxin oxidoreductase, subunit alpha (porA)
[Archaeoglobus fulgidus]
Length = 391
Score = 153 bits (384), Expect = 2e-36
Identities = 116/386 (30%), Positives = 189/386 (48%), Gaps = 32/386 (8%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKD--YYRAEEEYGA 77
+K + G + A +VK +V AYPITPQ+E + + +YA G + D Y AE E+GA
Sbjct: 2 RKVVRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFGA 61
Query: 78 MSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNV 137
S GL+ E + + G R+P VL R ++APLSI D+
Sbjct: 62 ASMLVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNRALSAPLSIWNDHQ 121
Query: 138 EISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELP 197
+ + ++G++ ++ EN Q+ D + ++E V LP ++ +G+ +THA V+L
Sbjct: 122 DSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMDGYKLTHAYEPVDLL 181
Query: 198 PE---DMKLPPRDP--YKAPVPPT--DCEIPPA-----RIQRDAPVQKSNFMSYLIHAVW 245
+ D LPP +P Y P C PP R+ ++++ + + W
Sbjct: 182 EQETVDSFLPPYEPAAYMTTKKPLAFGCYAPPHVYMEFRVAMQQAMERARKIMLDVFKEW 241
Query: 246 QQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGL 305
+ W GG I V PD+++FVVA G R+ EGL+VGL
Sbjct: 242 GELT------GRDW-----GGHITVDFPDSKIFVVAMGSVVGLLRKVVEELRGEGLSVGL 290
Query: 306 IKVKSLRPFPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAI--PNSGIVVDGPR 359
IK+++ RPFPV+E+REALK+A+ VIV + ++ G ++ E+K+AI +S +
Sbjct: 291 IKIRTFRPFPVEELREALKDAEKVIVLDRSVSFGYEGPVSIELKSAIYGHSSAEIYSFAV 350
Query: 360 VYGGMTLPVELIMEEIYKAFGIKKEK 385
GG +P + +E+I + +EK
Sbjct: 351 GLGGRDMPKD-FLEKIIRDVAEGREK 375
sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|2127892|pir||D64333 ferredoxin
oxidoreductase, alpha subunit - Methanococcus jannaschii
>gi|1590995 (U67482) pyruvate ferredoxin oxidoreductase,
subunit alpha (porA) [Methanococcus jannaschii]
Length = 389
Score = 150 bits (374), Expect = 2e-35
Identities = 103/340 (30%), Positives = 165/340 (48%), Gaps = 29/340 (8%)
Query: 14 LEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAE 72
+E E K ITG+ A AEA K A+VDV AYPITPQ+ + + + A G + +Y + E
Sbjct: 1 METMCEVKVITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLAEFVANGELDAEYIKVE 60
Query: 73 EEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSI 132
E+ AMS + GL E + G R+P V+ V R ++AP++I
Sbjct: 61 SEHSAMSACIGAAATGARTFTATASQGLALMHEMLFIASGMRLPIVMMVANRALSAPINI 120
Query: 133 QPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKG 192
D+ + +SG + ++ E+ Q+ D + + I+E DV LPV+V +GF +TH
Sbjct: 121 WNDHQDSIAERDSGWIQIYVEDNQETLDSIIQAYKIAENEDVLLPVMVCLDGFILTHTVE 180
Query: 193 YVELP-------------PEDMKLPPRDPY-KAPVPPTDCEIPPARIQRDAPVQKSNFMS 238
V +P P+ L P P + PV DC + R Q + ++++
Sbjct: 181 PVTIPKAERVREFLGVYEPKHAYLDPDRPITQGPVGVPDCYM-ETRKQIEEAMERA---- 235
Query: 239 YLIHAVWQQEVWSANRRAAKWIKH-YLGGLIEVVNPD-AEVFVVASGCAAAQGREAQRYA 296
++ + N A+W K Y GL+E N D A+ +VA G +
Sbjct: 236 -------KKVIRDVNEEFAEWFKRKYGNGLVEAYNLDNADTVLVAMGSVCGTIKYVIDEL 288
Query: 297 TMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNI 336
EG NVGL+++++ RPFP ++++E LK+A + V + NI
Sbjct: 289 KKEGKNVGLLRIRAFRPFPKEDVKELLKDANNIAVLDKNI 328
gi|2648476 (AE000961) 2-ketoisovalerate ferredoxin oxidoreductase, subunit
alpha (vorA) [Archaeoglobus fulgidus]
Length = 366
Score = 134 bits (333), Expect = 2e-30
Identities = 95/338 (28%), Positives = 159/338 (46%), Gaps = 20/338 (5%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKD-YYRAEEEYGAM 78
KK +T ++A AEAVK A DV AYPITPQS + + ++ G + + R E E+ AM
Sbjct: 14 KKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSAM 73
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
S GL E G R+P V+ + R + AP +I D+++
Sbjct: 74 GVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARSIGAPWNIHGDHLD 133
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
+ + + G ++ AEN Q+ FD TL F++SE+V++ PV VA +GF ++H VE+
Sbjct: 134 LMAMRDLGWIISVAENAQEAFDMTLNAFMLSEEVNI--PVAVAIDGFTMSHTAEVVEV-- 189
Query: 199 EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAK 258
++++PPR +P D + + + L +A+
Sbjct: 190 REVEIPPRKQAYRILPGMDVALNAVTFGEARMTARYDLAKDL-------------ENSAE 236
Query: 259 WIKHYLGGLIEVVN-PDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVD 317
I+ GGL+E DA+ VV +G + ++A EG+ +G++++K +RPFP
Sbjct: 237 LIEKEYGGLVERYRLEDADYAVVVTGGLSGDVKDAVDMLREEGVKMGVLRLKFIRPFPKK 296
Query: 318 EIREALKNAKAVIVPEHNIVGWLAKEVKA-AIPNSGIV 354
++ V ++ G L+ EV A + N +V
Sbjct: 297 AVKSLPSQVLVVDRANTDLRGTLSVEVAACGVENVNVV 334
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|2622870 (AE000929) pyruvate oxidoreductase,
alpha subunit [Methanobacterium thermoautotrophicum]
Length = 383
Score = 133 bits (332), Expect = 2e-30
Identities = 107/347 (30%), Positives = 154/347 (43%), Gaps = 32/347 (9%)
Query: 21 KFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMS 79
K I+ +QA AEA K A V YPITPQ+ + A G +K +Y R E E+ AMS
Sbjct: 4 KVISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSAMS 63
Query: 80 XXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEI 139
S GL E + + G R P V+ R ++APLSI D +
Sbjct: 64 ACVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSAPLSIWNDQQDS 123
Query: 140 SYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPE 199
+SG + ++ E+ Q+ D L + +SE DV LP +V +GF +TH V++P +
Sbjct: 124 IAERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIPSQ 183
Query: 200 ---DMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRA 256
D LP P + D P+ F + + EV A R+
Sbjct: 184 EDVDSFLPEFQ-------------PQVMLDPDEPMSLGTFTDPDYYMEARYEVEKAMERS 230
Query: 257 AKWIKHYLG----------GLIEVVN-PDAEVFVVASGCAAAQGREAQRYATMEGLNVGL 305
K I+ GL+E DAE+ +VA G + RE +G VGL
Sbjct: 231 RKIIERACREFSEMFGREYGLVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGKAVGL 290
Query: 306 IKVKSLRPFPVDEIREALKNAKAVIVPEHNIV----GWLAKEVKAAI 348
+KV+ RPFP +EI+ A++NA V V + NI G L E+ A +
Sbjct: 291 LKVRVHRPFPAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALL 337
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT)
Length = 392
Score = 124 bits (308), Expect = 1e-27
Identities = 93/327 (28%), Positives = 148/327 (44%), Gaps = 15/327 (4%)
Query: 14 LEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAE 72
+E E+ +TG++A A A+++ DV AYPITPQ+ + A G V+ + E
Sbjct: 1 MERVVERVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVE 60
Query: 73 EEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSI 132
E+ AMS S GL E + +R+P V+ V+ R ++ P++I
Sbjct: 61 SEHSAMSAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINI 120
Query: 133 QPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKG 192
D+ + +SG + L AE Q+ +DFT+ ++E DV LPV+V +GF ++H
Sbjct: 121 HCDHSDAMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVE 180
Query: 193 YVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSA 252
VE P+++ K P D E P P+ ++ Y H Q E
Sbjct: 181 PVEFYPDELVKKFVGELKPMYPLLDTEHPVTW----GPLDLYDY--YFEHKRQQIEAMEN 234
Query: 253 NRRA----AKWIKHYLGGLIEVVNP----DAEVFVVASGCAAAQGREAQRYATMEGLNVG 304
++ AK + G V P DAE +VA G + + EG VG
Sbjct: 235 VKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVG 294
Query: 305 LIKVKSLRPFPVDEIREALKNAKAVIV 331
+K+ RPFP ++++E L K+V+V
Sbjct: 295 SLKIWMFRPFPKEQLQELLNGRKSVVV 321
emb|CAA59457| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase
[Thermotoga maritima]
>gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate
ferredoxin oxidoreductase, alpha subunit [Thermotoga
maritima]
Length = 394
Score = 124 bits (308), Expect = 1e-27
Identities = 93/327 (28%), Positives = 148/327 (44%), Gaps = 15/327 (4%)
Query: 14 LEAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAE 72
+E E+ +TG++A A A+++ DV AYPITPQ+ + A G V+ + E
Sbjct: 3 MERVVERVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVE 62
Query: 73 EEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSI 132
E+ AMS S GL E + +R+P V+ V+ R ++ P++I
Sbjct: 63 SEHSAMSAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINI 122
Query: 133 QPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKG 192
D+ + +SG + L AE Q+ +DFT+ ++E DV LPV+V +GF ++H
Sbjct: 123 HCDHSDAMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVE 182
Query: 193 YVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSA 252
VE P+++ K P D E P P+ ++ Y H Q E
Sbjct: 183 PVEFYPDELVKKFVGELKPMYPLLDTEHPVTW----GPLDLYDY--YFEHKRQQIEAMEN 236
Query: 253 NRRA----AKWIKHYLGGLIEVVNP----DAEVFVVASGCAAAQGREAQRYATMEGLNVG 304
++ AK + G V P DAE +VA G + + EG VG
Sbjct: 237 VKKVFPEIAKEFEETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVG 296
Query: 305 LIKVKSLRPFPVDEIREALKNAKAVIV 331
+K+ RPFP ++++E L K+V+V
Sbjct: 297 SLKIWMFRPFPKEQLQELLNGRKSVVV 323
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|1197363|emb|CAA59505| (X85250) pyruvate
ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus]
Length = 396
Score = 122 bits (304), Expect = 4e-27
Identities = 103/387 (26%), Positives = 163/387 (41%), Gaps = 28/387 (7%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
+K + ++A A A K A V A+PITP + + + A G + ++ + E E+ A+
Sbjct: 4 RKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAI 63
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
S + GL E + G R+P V+ + R ++AP++I D +
Sbjct: 64 SACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
++G + +AEN Q+ D L + ++E V LP +V + F +TH VE+P
Sbjct: 124 TISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
Query: 199 EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAK 258
+++ D + P I PAR P+ + + + + VW A RA K
Sbjct: 184 QEVV----DEFLGEYEPKHAYIDPAR-----PITQGSLAFPAHYMESRYTVWEAMERAKK 234
Query: 259 WIKHYLG-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIK 307
I + E DA++ V G A E EG VG K
Sbjct: 235 VIDEAFAEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEGYKVGAAK 294
Query: 308 VKSLRPFPVDEIREALKNAKAVIVPEHNIV----GWLAKEVKAAIPNSG---IVVDGPRV 360
+ RPFPV+EIRE K AK + E NI G + + AA+ N ++VD
Sbjct: 295 ITVYRPFPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVG 354
Query: 361 YGGMTLPVELIMEEIYKAFGIKKEKKV 387
+GG + + E + A KE KV
Sbjct: 355 HGGRDVTFNQLDEALEIAEKALKEGKV 381
emb|CAB50271.1| (AJ248287) KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-)
(VOR) [Pyrococcus abyssi]
Length = 395
Score = 116 bits (289), Expect = 2e-25
Identities = 95/344 (27%), Positives = 149/344 (42%), Gaps = 16/344 (4%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
KK ++G+ A A AV A V V AYPITPQ+ + + + A G Y E E+ AM
Sbjct: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 67
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
+ S GL E + G R+P V+ + R + P S+ D +
Sbjct: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
++G + +AEN Q+V+D L F ++E V+V P +V F ++H V + P
Sbjct: 128 SLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNV--PAMVVESAFILSHTYEIVNMIP 185
Query: 199 EDMK---LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYL--IHAVWQQEVWSAN 253
+++ LPPR P + D E P A P F L H ++ +
Sbjct: 186 QELVDEFLPPRKPLYS---LADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVG 242
Query: 254 RR-AAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLR 312
R ++ + Y + + DA+ + G +EA +G VG KV+ R
Sbjct: 243 REFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFR 302
Query: 313 PFPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSG 352
PFP +E+ E ++ K + V + N G L E K A+ N+G
Sbjct: 303 PFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNG 346
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE ALPHA SUBUNIT)
Length = 394
Score = 116 bits (288), Expect = 3e-25
Identities = 92/345 (26%), Positives = 149/345 (42%), Gaps = 16/345 (4%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
KK ++G+ A A A A V V AYPITPQ+ + + + A G Y E E+ AM
Sbjct: 7 KKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 66
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
+ S GL E + G R+P V+ + R + P S+ D +
Sbjct: 67 AACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQTD 126
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
++G + +AEN Q+V+D L + ++E V++ P ++ F ++H V + P
Sbjct: 127 SLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNI--PTMIIESAFILSHTYEVVNMIP 184
Query: 199 EDMK---LPPRDPYKAPVPPTDCEIPPA--RIQRDAPVQKSNFMSYLIHAVWQQEVWSAN 253
+++ LPPR P TD E P A + A + + H ++ + S
Sbjct: 185 QELVDEFLPPRKPL---YTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVG 241
Query: 254 RRAAKWIKHYLGGLIEV-VNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLR 312
+ + +IE DA+ + G +EA EG VG KV+ R
Sbjct: 242 KEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFR 301
Query: 313 PFPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSGI 353
PFP +E+ E ++ K + V + N G L E K A+ N+G+
Sbjct: 302 PFPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGV 346
dbj|BAA29771| (AP000003) 397aa long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 397
Score = 116 bits (288), Expect = 3e-25
Identities = 92/345 (26%), Positives = 149/345 (42%), Gaps = 16/345 (4%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
KK ++G+ A A A A V V AYPITPQ+ + + + A G Y E E+ AM
Sbjct: 10 KKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 69
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
+ S GL E + G R+P V+ + R + P S+ D +
Sbjct: 70 AACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQTD 129
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
++G + +AEN Q+V+D L + ++E V++ P ++ F ++H V + P
Sbjct: 130 SLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNI--PTMIIESAFILSHTYEVVNMIP 187
Query: 199 EDMK---LPPRDPYKAPVPPTDCEIPPA--RIQRDAPVQKSNFMSYLIHAVWQQEVWSAN 253
+++ LPPR P TD E P A + A + + H ++ + S
Sbjct: 188 QELVDEFLPPRKPL---YTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVG 244
Query: 254 RRAAKWIKHYLGGLIEV-VNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLR 312
+ + +IE DA+ + G +EA EG VG KV+ R
Sbjct: 245 KEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFR 304
Query: 313 PFPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSGI 353
PFP +E+ E ++ K + V + N G L E K A+ N+G+
Sbjct: 305 PFPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGV 349
gi|2853363 (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit
[Helicobacter pylori]
Length = 396
Score = 114 bits (283), Expect = 1e-24
Identities = 86/334 (25%), Positives = 153/334 (45%), Gaps = 13/334 (3%)
Query: 25 GSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXX 83
G+ A + A+++A +DV AYPITP + + G GY+ ++ E E+ AMS
Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSACVG 74
Query: 84 XXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLL 143
S GL +E + G R+P VL ++ R + APL+I D+ ++
Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMYLSR 134
Query: 144 NSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKL 203
+SG + L N Q+ +DFTL F I+E V +P +V +GF +H V + +
Sbjct: 135 DSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDAVAY 194
Query: 204 PPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQ-----QEVWSANRRAAK 258
Y+ D + P + + + L HA+ +EV++ +
Sbjct: 195 QFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAKLT- 253
Query: 259 WIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDE 318
+++L ++ DAE+ + A G A + +G+ G+ + SLRPFP ++
Sbjct: 254 GRQYHLTKTFQL--EDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYEK 311
Query: 319 IREALKNAKAVIVPEHN----IVGWLAKEVKAAI 348
+ + LKN KA+ + + + +G + EV +A+
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAV 345
gi|4155626 (AE001531) Pyruvate ferrodoxin oxidoreductase [Helicobacter pylori
J99]
Length = 407
Score = 114 bits (282), Expect = 2e-24
Identities = 87/334 (26%), Positives = 152/334 (45%), Gaps = 13/334 (3%)
Query: 25 GSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXX 83
G+ A + A+++A +DV AYPITP + + G GYV ++ E E+ AMS
Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74
Query: 84 XXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLL 143
S GL +E + G R+P VL ++ R + APL+I D+ ++
Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMYLSR 134
Query: 144 NSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKL 203
+SG + L N Q+ +DFTL F I+E V +P +V +GF +H V + +
Sbjct: 135 DSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDAVAY 194
Query: 204 PPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQ-----QEVWSANRRAAK 258
Y+ D + P + + + L HA+ +EV++ +
Sbjct: 195 QFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAKLT- 253
Query: 259 WIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDE 318
+++L ++ DAE+ + A G A + +G+ G+ + SLRPFP +
Sbjct: 254 GRQYHLTKTFQL--EDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311
Query: 319 IREALKNAKAVIVPEHN----IVGWLAKEVKAAI 348
+ + LKN KA+ + + + +G + EV +A+
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAV 345
gb|AAD08154.1| (AE000617) pyruvate ferredoxin oxidoreductase, alpha subunit
[Helicobacter pylori 26695]
Length = 407
Score = 114 bits (282), Expect = 2e-24
Identities = 87/334 (26%), Positives = 152/334 (45%), Gaps = 13/334 (3%)
Query: 25 GSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXX 83
G+ A + A+++A +DV AYPITP + + G GYV ++ E E+ AMS
Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSACVG 74
Query: 84 XXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLL 143
S GL +E + G R+P VL ++ R + APL+I D+ ++
Sbjct: 75 AAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMYLSR 134
Query: 144 NSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKL 203
+SG + L N Q+ +DFTL F I+E V +P +V +GF +H V + +
Sbjct: 135 DSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDAVAY 194
Query: 204 PPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQ-----QEVWSANRRAAK 258
Y+ D + P + + + L HA+ +EV++ +
Sbjct: 195 QFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAKLT- 253
Query: 259 WIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDE 318
+++L ++ DAE+ + A G A + +G+ G+ + SLRPFP +
Sbjct: 254 GRQYHLTKTFQL--EDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311
Query: 319 IREALKNAKAVIVPEHN----IVGWLAKEVKAAI 348
+ + LKN KA+ + + + +G + EV +A+
Sbjct: 312 LGQDLKNLKALAILDKSSPAGTMGAMFNEVTSAV 345
emb|CAA69455| (Y08256) pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus
solfataricus]
Length = 415
Score = 111 bits (276), Expect = 8e-24
Identities = 87/348 (25%), Positives = 152/348 (43%), Gaps = 24/348 (6%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXX 81
+ G+QA A A A+VDV AYPI P +E M + L A G + ++ AE E+G
Sbjct: 14 MNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFETV 73
Query: 82 XXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISY 141
SG G L +EAIV R P V + R ++ P + ++ +
Sbjct: 74 KHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDALM 133
Query: 142 LLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDM 201
+ + G +++ + Q+ FD L + I+E V LP+ ++ +G F+TH++ V LPP ++
Sbjct: 134 VRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPREL 193
Query: 202 K---LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAK 258
LPP + K V P + ++ D ++ + + + A K
Sbjct: 194 VKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERA-RSVIVEAYEEFKK 252
Query: 259 WIKHYLGGLIEVVNP-----------DAEVFVVASGCAAAQGREAQRYATMEGLNVGLIK 307
Y G ++ P DAEV ++ G + + A + +G VG+++
Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312
Query: 308 VKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVV 355
++ RPFP ++ L N++ V V + ++ PN G V+
Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCV--------IDRDYSMGSPNRGGVI 352
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE ALPHA SUBUNIT) >gi|1197360|emb|CAA59502|
(X85250) 2-ketovalerate ferredoxin oxidoreductase
alpha-2 [Pyrococcus furiosus]
Length = 394
Score = 110 bits (273), Expect = 2e-23
Identities = 89/341 (26%), Positives = 145/341 (42%), Gaps = 12/341 (3%)
Query: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
+K ++G+ A A A A V V AYPITPQ+ + + + A G Y E E+ AM
Sbjct: 7 RKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 66
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
+ S GL E + G R+P V+ + R + P S+ D +
Sbjct: 67 AACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 126
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
++G + +AEN Q+V+D L + ++E V+V P +V F ++H VE+ P
Sbjct: 127 SLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNV--PAMVVESAFILSHTYDVVEMIP 184
Query: 199 EDMK---LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRR 255
+++ LPPR P + + D I + + + H ++ + +
Sbjct: 185 QELVDEFLPPRKPLYS-LANFDEPIAVGALATPNDYYEFRYKLAKAHEEAKKVIKEVGKE 243
Query: 256 AAKWIKHYLGGLIEV-VNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPF 314
+ +IE DA+ + G +EA EG VG KV+ RPF
Sbjct: 244 FGERFGRDYSQMIETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRPF 303
Query: 315 PVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNS 351
P +E+ E ++ K + V + N G L E K A+ NS
Sbjct: 304 PKEELVEIAESVKGIAVLDRNFSFGQEGILFTESKGALYNS 344
emb|CAB50268.1| (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1) (PYRUVATE
OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus abyssi]
Length = 395
Score = 109 bits (271), Expect = 3e-23
Identities = 94/378 (24%), Positives = 156/378 (40%), Gaps = 32/378 (8%)
Query: 26 SQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXXX 84
++A A A K A V A+PITP + + + A G + ++ + E E+ A+S
Sbjct: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69
Query: 85 XXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLLN 144
+ GL E + G R+P V+ + R ++AP++I D + +
Sbjct: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129
Query: 145 SGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLP 204
+G + +AEN Q+ D L + ++E V LP +V + F +TH VE+P +++
Sbjct: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-- 187
Query: 205 PRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYL 264
D + P + P R P+ + + + VW A A K I
Sbjct: 188 --DEFLGEYEPKHAYLDPKR-----PITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
Query: 265 G-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRP 313
+ E DAE+ V G A ++ EG VG K+ RP
Sbjct: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
Query: 314 FPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSG---IVVDGPRVYGGMTL 366
FPV+EIRE K K + E +I G + + AA+ N +++D GG
Sbjct: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGR-- 358
Query: 367 PVELIMEEIYKAFGIKKE 384
++ ++ +A I KE
Sbjct: 359 --DVTFNQLDEALSIAKE 374
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT)
Length = 395
Score = 108 bits (266), Expect = 1e-22
Identities = 83/335 (24%), Positives = 140/335 (41%), Gaps = 29/335 (8%)
Query: 26 SQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXXX 84
++A A A K A V A+PITP + + + A G + ++ + E E+ A+S
Sbjct: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAVVGA 69
Query: 85 XXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLLN 144
+ GL E + G R+P V+ + R ++AP++I D + +
Sbjct: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWNDWQDSISQRD 129
Query: 145 SGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLP 204
+G + +AEN Q+ D L + ++E V LP +V + F +TH VE+P +++
Sbjct: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-- 187
Query: 205 PRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYL 264
D + P + P R P+ + + + VW A +A K I
Sbjct: 188 --DEFLGEYEPKHAYLDPKR-----PITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 240
Query: 265 G-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRP 313
+ E DAE+ V G A ++ EG VG K+ RP
Sbjct: 241 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
Query: 314 FPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAI 348
FPV+EIR K AK ++G++ K++ +
Sbjct: 301 FPVEEIRALAKKAK--------VLGFIEKDISIGL 327
dbj|BAA29775| (AP000003) 398aa long hypothetical ferredoxin oxidoreductase
alpha-2 subunit [Pyrococcus horikoshii]
Length = 398
Score = 108 bits (266), Expect = 1e-22
Identities = 83/335 (24%), Positives = 140/335 (41%), Gaps = 29/335 (8%)
Query: 26 SQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXXX 84
++A A A K A V A+PITP + + + A G + ++ + E E+ A+S
Sbjct: 13 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAVVGA 72
Query: 85 XXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLLN 144
+ GL E + G R+P V+ + R ++AP++I D + +
Sbjct: 73 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWNDWQDSISQRD 132
Query: 145 SGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLP 204
+G + +AEN Q+ D L + ++E V LP +V + F +TH VE+P +++
Sbjct: 133 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-- 190
Query: 205 PRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYL 264
D + P + P R P+ + + + VW A +A K I
Sbjct: 191 --DEFLGEYEPKHAYLDPKR-----PITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 243
Query: 265 G-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRP 313
+ E DAE+ V G A ++ EG VG K+ RP
Sbjct: 244 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 303
Query: 314 FPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAI 348
FPV+EIR K AK ++G++ K++ +
Sbjct: 304 FPVEEIRALAKKAK--------VLGFIEKDISIGL 330
gi|2935172 (AF021092) PorA subunit of pyruvate:flavodoxin oxidoreductase
[Helicobacter pylori]
Length = 408
Score = 87.4 bits (213), Expect = 2e-16
Identities = 76/314 (24%), Positives = 132/314 (41%), Gaps = 10/314 (3%)
Query: 25 GSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSXXXX 83
G+ A + A+++A +DV AYPITP + + G GY+ D+ E E+ AMS
Sbjct: 15 GNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGDFALVESEHAAMSACVG 74
Query: 84 XXXXXXXXXXXXSGPGL-LRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYL 142
S G + G I G R V ++ R + APL+I D+ ++
Sbjct: 75 AAAAGGRVSTATSSQGSGVNGRGFITKVSGMRSAIVGNLVNRALAAPLNIHGDHSDMYLS 134
Query: 143 LNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMK 202
+SG + L N Q+ +DFTL F + E V +P +V +GF +H V + +
Sbjct: 135 RDSGWISLCTCNPQEAYDFTLMAFKLGEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDGVA 194
Query: 203 LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQ-----QEVWSANRRAA 257
Y+ D + P + + + L HA+ +EV++ +
Sbjct: 195 YQFVGEYQTKHSLVDFDKPVSYGAQAEEEWHYEHKARLHHAIMSASSVIEEVFNDFAKLT 254
Query: 258 KWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVD 317
+++L ++ DAE+ + A G A + +G+ G+ + S P +
Sbjct: 255 -GRQYHLTKTFQL--EDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSCAPSLMR 311
Query: 318 EIREALKNAKAVIV 331
+ LKN KA+ +
Sbjct: 312 RLGRDLKNLKALAI 325
dbj|BAA30778| (AP000006) 408aa long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 408
Score = 85.8 bits (209), Expect = 5e-16
Identities = 99/381 (25%), Positives = 155/381 (39%), Gaps = 39/381 (10%)
Query: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ--GYVKDYYRAEEEYGAMS 79
F+ G +A A A YPITP SE + + GY Y + E+E G+++
Sbjct: 36 FMMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGY---YLQMEDEIGSIA 92
Query: 80 XXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTR----VVNAPLSIQPD 135
SGPG E I P V+ + R A Q D
Sbjct: 93 AMIGASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATKGAQGD 152
Query: 136 NVEISYLLNSG--LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
+ + + ++ + + +D F T+ F I+EK+ PV+V +G + H +
Sbjct: 153 FFQARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRT--PVIVLFDGI-LGHTREQ 209
Query: 194 VELPP---------------EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238
+ +P E+ KLP DP+ VPP +P V S
Sbjct: 210 IRIPDPDEVEITYRKLPGSEEEAKLPFGDPHGDGVPP----MPLFGHGYFTHVTGSTHKE 265
Query: 239 YLIHAVWQQEVWSAN----RRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQR 294
+ V+ QEV R + + E DAE+ VV+ G +A A
Sbjct: 266 NGLRDVYTQEVHDKLVRRIHRKIEQNRDVYEKYEEYYTDDAEILVVSWGVSARPSLGAVL 325
Query: 295 YATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIV 354
A EG+ GL K++ PFP + +RE K +A++VPE N+ G + EV+ + N ++
Sbjct: 326 KAREEGIKAGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMVLEVQRFV-NDDVI 383
Query: 355 VDGPRVYGGMTLPVELIMEEI 375
+ G GG+ L VE I++EI
Sbjct: 384 LKGVNKIGGVPLTVEEILKEI 404
emb|CAB49426.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
(korA-1) [Pyrococcus abyssi]
Length = 408
Score = 82.7 bits (201), Expect = 5e-15
Identities = 98/381 (25%), Positives = 154/381 (39%), Gaps = 39/381 (10%)
Query: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ--GYVKDYYRAEEEYGAMS 79
F+ G +A A A YPITP SE + + GY Y + E+E +++
Sbjct: 36 FMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELPKVGGY---YLQMEDEIASIA 92
Query: 80 XXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTR----VVNAPLSIQPD 135
SGPG E + P VL + R A Q D
Sbjct: 93 AMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGD 152
Query: 136 NVEISYLLNSG--LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
+ + + +V + + +D F T+ F ++E++ PVVV +G + H +
Sbjct: 153 FFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRT--PVVVLFDGI-LGHTREQ 209
Query: 194 VELPP---------------EDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238
+ +P E+ +LP DP+ VPP +P V S
Sbjct: 210 IRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPP----MPLFGHGYFTHVTGSTHKE 265
Query: 239 YLIHAVWQQEVWSAN----RRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQR 294
+ V+ QEV R + + E DAE+ VV+ G +A A
Sbjct: 266 NGLRDVYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVL 325
Query: 295 YATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIV 354
A EG+ VGL K++ PFP + +RE K +A++VPE N+ G + EV+ + N ++
Sbjct: 326 KARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL-GQMILEVQRFV-NDDVL 383
Query: 355 VDGPRVYGGMTLPVELIMEEI 375
+ G GG+ L VE I+ EI
Sbjct: 384 LKGVNKIGGVPLTVEEILREI 404
gi|3746570 (AF061850) putative pyruvate oxidoreductase; POR [Brachyspira
pilosicoli]
Length = 275
Score = 81.9 bits (199), Expect = 8e-15
Identities = 69/259 (26%), Positives = 112/259 (42%), Gaps = 30/259 (11%)
Query: 74 EYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQ 133
E+GA S GLL +E + G R P VL V+ R V+ PL I+
Sbjct: 17 EHGAAGICYGATTAGGRVFNATSANGLLFAMEQLPVQAGTRFPMVLNVVNRTVSGPLDIK 76
Query: 134 PDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
D +I LN+G +++ A Q V+DF + I+EK LP++V+++GFF +H K
Sbjct: 77 CDQSDIMMALNTGWIIIMAHTTQMVYDFNIFALKIAEKAK--LPIIVSSDGFFTSHQKKK 134
Query: 194 VELPPEDM-------KLPPR----DPYKAPVP----PTDCEIPPARIQRDAPVQKSNFMS 238
+ L D K P +P K PV + E+ +++Q ++ S
Sbjct: 135 IHLFKNDKDVQDFLGKYTPEVTSVEPTKNPVTIGPYMNEDELTGSKLQLSQALEDSR--- 191
Query: 239 YLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREA--QRYA 296
+I V+++ + R+ + H + G AEV ++ G A G A +
Sbjct: 192 AIIAEVFEEFASLSGRKYSPIETHNMEG--------AEVALMLCGSAYETGTLAVDEMRK 243
Query: 297 TMEGLNVGLIKVKSLRPFP 315
L +G + +RPFP
Sbjct: 244 ANPNLKIGAFAITQIRPFP 262
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE BETA SUBUNIT)
Length = 352
Score = 73.7 bits (178), Expect = 2e-12
Identities = 79/307 (25%), Positives = 125/307 (39%), Gaps = 24/307 (7%)
Query: 21 KFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSX 80
+ + G+ A A D YPITP SE +H Y + + +AE E A++
Sbjct: 4 QMVKGNTAVIIGAMYAGCDCYFGYPITPASEILH-EASRYFPMVGRKFVQAESEEAAINM 62
Query: 81 XXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEIS 140
SGPG+ E I G +PAV+ + R +I P+ + +
Sbjct: 63 VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 122
Query: 141 YLLNSG------LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYV 194
++ G +VL + Q++ D T+ F +++K PVVV T+ A+ +
Sbjct: 123 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADK--YRNPVVVLTDAVLGQMAEP-L 179
Query: 195 ELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANR 254
P E ++ P + + I D + F YL QE ++
Sbjct: 180 RFPEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFD-ELEEFNFYL------QEKYARIE 232
Query: 255 RAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPF 314
+ YL DAE+ +VA G ++ R A A EG+NVGL++ +L PF
Sbjct: 233 ENEVRYEEYL-------VDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPF 285
Query: 315 PVDEIRE 321
P D IRE
Sbjct: 286 PSDRIRE 292
gi|2621790 (AE000849) 2-oxoisovalerate oxidoreductase, beta subunit
[Methanobacterium thermoautotrophicum]
Length = 348
Score = 73.4 bits (177), Expect = 3e-12
Identities = 79/305 (25%), Positives = 124/305 (39%), Gaps = 24/305 (7%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSXXX 82
+ G+ A A D YPITP SE +H Y + + +AE E A++
Sbjct: 2 VKGNTAVIIGAMYAGCDCYFGYPITPASEILH-EASRYFPMVGRKFVQAESEEAAINMVY 60
Query: 83 XXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYL 142
SGPG+ E I G +PAV+ + R +I P+ + + +
Sbjct: 61 GAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQI 120
Query: 143 LNSG------LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVEL 196
+ G +VL + Q++ D T+ F +++K PVVV T+ A+ +
Sbjct: 121 VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADK--YRNPVVVLTDAVLGQMAEP-LRF 177
Query: 197 PPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRA 256
P E ++ P + + I D + F YL QE ++
Sbjct: 178 PEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFD-ELEEFNFYL------QEKYARIEEN 230
Query: 257 AKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPV 316
+ YL DAE+ +VA G ++ R A A EG+NVGL++ +L PFP
Sbjct: 231 EVRYEEYL-------VDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPS 283
Query: 317 DEIRE 321
D IRE
Sbjct: 284 DRIRE 288
dbj|BAA30774| (AP000006) 385aa long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 385
Score = 72.2 bits (174), Expect = 7e-12
Identities = 92/389 (23%), Positives = 145/389 (36%), Gaps = 62/389 (15%)
Query: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSXX 81
FI G +A A A A YPITP SE + LY + E+E G+++
Sbjct: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLIDGVVIQMEDEIGSIAAV 70
Query: 82 XXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISY 141
SGPG E I P V+ + R P + QP
Sbjct: 71 IGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQR--GGPSTGQPTLPSQGD 128
Query: 142 LLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
++ S L+VL Q+ FDFT+ F ++EK Y V+ V H +
Sbjct: 129 IMQSIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185
Query: 194 VELP---------------PEDMKLPPRDPYKAPVPPT----------------DCEIPP 222
V +P E+ KLP DP+ VPP D + P
Sbjct: 186 VYIPEPDEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRP 245
Query: 223 ARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVAS 282
++R+ +H + ++ + K I Y ++ DAE+ +V +
Sbjct: 246 RTVERE------------VHERLIRRIFEKIEKNKKDIFDYEARELD----DAEIAIVTT 289
Query: 283 GCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAK 342
G A A + G+ GL+K+ ++ PF + I + + + + VPE N+ G L
Sbjct: 290 GIVARSALRAIKELRNLGIKAGLLKINTIWPFDFELIEKVAEKVERIYVPEMNL-GQLYH 348
Query: 343 EVKAAIPNSGIVVDGPRVYGGMTLPVELI 371
VK V ++ G + P+E+I
Sbjct: 349 LVKEGANGKAEVKLISKIGGEVHTPMEII 377
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
OXIDOREDUCTASE ALPHA CHAIN) (KOR)
(2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
>gi|2127893|pir||E64334 ferredoxin oxidoreductase, alpha
subunit - Methanococcus jannaschii >gi|1592279 (U67483)
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
(korA) [Methanococcus jannaschii]
Length = 366
Score = 69.1 bits (166), Expect = 6e-11
Identities = 95/375 (25%), Positives = 154/375 (40%), Gaps = 43/375 (11%)
Query: 21 KFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ--GYVKDYYRAEEEYGAM 78
+F+ G+QA A+ +A YPITP +E + + GY Y + E+E G++
Sbjct: 4 EFMQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELPKVGGY---YIQMEDEIGSI 60
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
+ SGPG E I P V+ + R P + QP
Sbjct: 61 AAVIGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQR--GGPSTGQPTMAS 118
Query: 139 ISYLLNSG--------LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
++ ++ L + Q+++DFT+ F +EK + PV V + V H
Sbjct: 119 QGDMMQCRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRI--PVFVMADEI-VGHM 175
Query: 191 KGYVELPPE----DMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQ 246
+ V L + K P P K P P D IP + PV + ++
Sbjct: 176 REKVILHDNIEIINRKKPEEKPCKKPYP-FDKLIP------EMPVFGEGYNVHITGLTHD 228
Query: 247 QEVW---------SANRRAAKWIKHYLGGLI--EVVNPDAEVFVVASGCAAAQGREAQRY 295
+ + RR I+ +I E N DAE+ V G + + A R
Sbjct: 229 ERGYPDVSPETHDKLVRRIVNKIRKNKDEIIKWEGENLDAEIVFVCYGSPSRTVKHAVRN 288
Query: 296 ATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVV 355
+GL+VG I++ ++ PFP D++ + LK AK V+VPE N+ G + EV+ + V+
Sbjct: 289 LREKGLDVGYIRLITVYPFP-DDLLKKLK-AKKVVVPEMNL-GQIYYEVERVCKKAEEVI 345
Query: 356 DGPRVYGGMTLPVEL 370
++ G + P EL
Sbjct: 346 LVDKIGGELHRPEEL 360
gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidoreductase [Spironucleus
barkhanus]
Length = 1182
Score = 67.9 bits (163), Expect = 1e-10
Identities = 71/298 (23%), Positives = 117/298 (38%), Gaps = 32/298 (10%)
Query: 39 DVAIAYPITPQSETMHLVGDLYAQGYVKDY---YRAEE---EYGAMSXXXXXXXXXXXXX 92
D ++ +PI+P S LV + ++G + + +R E E GA
Sbjct: 16 DNSLIFPISPSSPMAELVDEWASKGRLNAFDQVHRVTELNHEGGAAGALHGALLNGSLSS 75
Query: 93 XXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLSIQPDNVEISYLLNSGLVVLH 151
+ GLL + + +P VL V R + LSI D+ +I + +G+ +L
Sbjct: 76 TYTASQGLLLMIPNLYKMAAEHLPGVLHVAARTIATHSLSIHGDHSDIMAIKQTGISILV 135
Query: 152 AENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLPPRDPYKA 211
+ + Q+ DF L + + D P + A +G+ +H VE+ D K+ P PY+
Sbjct: 136 SPDVQEAMDFALVAHIAAINADT--PFIHAFDGYRTSHTIKKVEVISYD-KIKPFVPYE- 191
Query: 212 PVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHY-------- 263
+I R + + + S + VW Q + N +K + H+
Sbjct: 192 -------KIAEFRHKSLNSQRPEAYGSCMGPPVWMQSQEADNLHYSKILGHFEDAFVTVE 244
Query: 264 --LGGLIEVVN----PDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFP 315
G EV+ DA +V G RE Y +G VG I + RPFP
Sbjct: 245 KITGRKYEVIQYHGCADATDVIVIMGSGCITVRETVDYLNAQGRKVGAIFINLFRPFP 302
sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
OXIDOREDUCTASE ALPHA CHAIN) (KOR)
(2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
>gi|2650159 (AE001072) 2-ketoglutarate ferredoxin
oxidoreductase, subunit alpha (korA) [Archaeoglobus
fulgidus]
Length = 346
Score = 67.9 bits (163), Expect = 1e-10
Identities = 87/363 (23%), Positives = 147/363 (39%), Gaps = 35/363 (9%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAM 78
E + I G++A A + YPITP SE H + +L + + + + E+E ++
Sbjct: 2 EMELIQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPK-FGGVFIQMEDEIASI 60
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVL------GVMTRVVNAPLSI 132
S SGPG E + P V+ G T + AP
Sbjct: 61 SAVIGASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPS-- 118
Query: 133 QPDNVEISYLLNSG--LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
Q D ++ Y + +VVL + +D++ T+ F I+ + PV+V ++ V H
Sbjct: 119 QGDAMQARYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFST--PVIVLSDEI-VGHM 175
Query: 191 KGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVW 250
+ V LPP L + Y+ I R R V N + ++
Sbjct: 176 RESVALPP----LGEIESYEKRAKNL---IDGRRRHRTGLVHTENGLPTTDLEEYE---- 224
Query: 251 SANRRAAKWIKHYLGGLIEVVNPDAE--VFVVASGCAAAQGREAQRYATMEGLNVGLIKV 308
+ + + +V + E V VA G + + + + +G++ G++K+
Sbjct: 225 ----KLLRLLFAKFDDFRPMVRFEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSAGILKL 280
Query: 309 KSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRVYGGMTLPV 368
+SL PFP D +R K A V+VPE N G + KEV+ V G +G + LP
Sbjct: 281 ESLFPFPEDAVRRYSKKADLVVVPEMN-AGQVVKEVERV---CCCRVKGVSYFGSLILPE 336
Query: 369 ELI 371
+L+
Sbjct: 337 KLV 339
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
OXIDOREDUCTASE ALPHA CHAIN) (KOR)
(2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
Length = 376
Score = 66.7 bits (160), Expect = 3e-10
Identities = 88/381 (23%), Positives = 152/381 (39%), Gaps = 43/381 (11%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLY-AQGYVKDYYRAEEEYGA 77
E+ FI G+ A A +A YPITP +E + L +G V + + E+E GA
Sbjct: 3 EEYFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGV--FVQMEDEIGA 60
Query: 78 MSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNV 137
+ SGPG E + P V+ + R +P + QP
Sbjct: 61 LGAVIGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQR--GSPSTGQPTMA 118
Query: 138 EISYLLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTH 189
S ++ + ++ L + Q+ FDFT+ F ++E+ V PV+V + V H
Sbjct: 119 SQSDMMQARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGH 175
Query: 190 AKGYVELPP-------EDMKLPPRD--PYKAP---VPPTDC-----EIPPARIQRDAPVQ 232
+ + +P +PP + P+ AP VP IP + D
Sbjct: 176 MREKITIPDRVKIRKRRGPSVPPEEFLPFSAPEDGVPEMPAFGDGYRIPVTGLTHDEGGY 235
Query: 233 KSNFMSYLIHAVWQQEVWSANRRAAKWIKH--YLGGLIEVVNPDAEVFVVASGCAAAQGR 290
H + R K ++H + + E + DA + V++ G +
Sbjct: 236 PDASNPEGHHRL-------VKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVA 288
Query: 291 EAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPN 350
A + A +G+ G +K+ + PFP E+R A + + ++V E N+ G + EV+
Sbjct: 289 TAVKMAREDGVRAGYLKINTPWPFPETEVRAAAERSGKLLVVEMNL-GQMFYEVQRVAAG 347
Query: 351 SGIVVDGPRVYGGMTLPVELI 371
V P++ G + P E++
Sbjct: 348 MAEVELLPKIGGEIHRPEEIL 368
gi|2622136 (AE000875) 2-oxoglutarate oxidoreductase, alpha subunit
[Methanobacterium thermoautotrophicum]
Length = 378
Score = 66.7 bits (160), Expect = 3e-10
Identities = 88/381 (23%), Positives = 152/381 (39%), Gaps = 43/381 (11%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLY-AQGYVKDYYRAEEEYGA 77
E+ FI G+ A A +A YPITP +E + L +G V + + E+E GA
Sbjct: 5 EEYFIQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPREGGV--FVQMEDEIGA 62
Query: 78 MSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNV 137
+ SGPG E + P V+ + R +P + QP
Sbjct: 63 LGAVIGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQR--GSPSTGQPTMA 120
Query: 138 EISYLLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTH 189
S ++ + ++ L + Q+ FDFT+ F ++E+ V PV+V + V H
Sbjct: 121 SQSDMMQARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGH 177
Query: 190 AKGYVELPP-------EDMKLPPRD--PYKAP---VPPTDC-----EIPPARIQRDAPVQ 232
+ + +P +PP + P+ AP VP IP + D
Sbjct: 178 MREKITIPDRVKIRKRRGPSVPPEEFLPFSAPEDGVPEMPAFGDGYRIPVTGLTHDEGGY 237
Query: 233 KSNFMSYLIHAVWQQEVWSANRRAAKWIKH--YLGGLIEVVNPDAEVFVVASGCAAAQGR 290
H + R K ++H + + E + DA + V++ G +
Sbjct: 238 PDASNPEGHHRL-------VKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVA 290
Query: 291 EAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPN 350
A + A +G+ G +K+ + PFP E+R A + + ++V E N+ G + EV+
Sbjct: 291 TAVKMAREDGVRAGYLKINTPWPFPETEVRAAAERSGKLLVVEMNL-GQMFYEVQRVAAG 349
Query: 351 SGIVVDGPRVYGGMTLPVELI 371
V P++ G + P E++
Sbjct: 350 MAEVELLPKIGGEIHRPEEIL 370
emb|CAB49429.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
(korA-2) [Pyrococcus abyssi]
Length = 385
Score = 66.3 bits (159), Expect = 4e-10
Identities = 91/389 (23%), Positives = 141/389 (35%), Gaps = 62/389 (15%)
Query: 22 FITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAMSXX 81
FI G +A A A A YPITP SE + LY + E+E +++
Sbjct: 12 FIQGDEAIARAAILAGCRFYAGYPITPASEIFEAMA-LYMPLVDGVVIQMEDEIASIAAI 70
Query: 82 XXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISY 141
SGPG E I P V+ + R P + QP
Sbjct: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQR--GGPSTGQPTLPSQGD 128
Query: 142 LLNS--------GLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
++ S L+VL Q+ FDFT+ F ++EK Y V+ V H +
Sbjct: 129 IMQSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEK---YRTPVILLSDAEVGHMRER 185
Query: 194 VELP---------------PEDMKLPPRDPYKAPVPPT----------------DCEIPP 222
V +P E+ KLP DP+ VPP D P
Sbjct: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP 245
Query: 223 ARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVAS 282
++R+ +H + + R K I Y ++ DAEV +V +
Sbjct: 246 RTVERE------------VHERVIRRIVEKIERNKKDIFDYEARELD----DAEVAIVTT 289
Query: 283 GCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAK 342
G A A + G+ GL+K+ ++ PF + I + + + VPE N+ G L
Sbjct: 290 GIVARSALRAIKELRELGIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMNL-GQLYH 348
Query: 343 EVKAAIPNSGIVVDGPRVYGGMTLPVELI 371
V+ V ++ G + P+E++
Sbjct: 349 LVREGANGKAEVKLISKIGGEVHTPMEIV 377
sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|628896|pir||S41961 pyruvate
oxidoreductase - Rhodospirillum rubrum
>gi|453436|emb|CAA54651| (X77515) pyruvate
oxidoreductase [Rhodospirillum rubrum]
Length = 1191
Score = 63.2 bits (151), Expect = 3e-09
Identities = 92/377 (24%), Positives = 141/377 (36%), Gaps = 42/377 (11%)
Query: 18 REKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGY------VKDYYRA 71
R+ I G++A A R + +VA+ YPITP S L + A+G V
Sbjct: 4 RKMVAIDGNEACASVAYRVS-EVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEM 62
Query: 72 EEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTR-VVNAPL 130
+ E GA + GLL + + G P + V R + L
Sbjct: 63 QSEGGAAGACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHAL 122
Query: 131 SIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
SI D ++ +G +L + + Q+ D LA ++ +P + +GF +H
Sbjct: 123 SIFGDQSDVMACRQTGFAILASASVQEAHD--LASVAHGASLESRIPFLHFFDGFRTSHE 180
Query: 191 KGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSY---------LI 241
+EL +D D P + R F
Sbjct: 181 VNKIELMTDDDLHAMIDDDLVAAHRARALTPDTPVTRGTAQNPDTFFQAQEARNPFYDAC 240
Query: 242 HAVWQQEVWSANRRAAKWIKHYLGGLIEVV-NPDAEVFVVASGCAAAQGREAQRYATMEG 300
A+ Q + +R AA + Y GL + V +P AE VV G A E + G
Sbjct: 241 PAIVQSYM---DRLAALTGRRY--GLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARG 295
Query: 301 LNVGLIKVKSLRPFPVDEIREALK-NAKAVIVPEH-------------NIVGWLAKEVKA 346
+G++KV+ RPF VD AL + +A+ V + ++VG LA+ KA
Sbjct: 296 EKIGVVKVRLFRPFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALAR-AKA 354
Query: 347 AIPNSGIVVDGPRVYGG 363
+GIV P V GG
Sbjct: 355 LGLRAGIV--DPAVIGG 369
sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE
>gi|1742250|dbj|BAA14982| (D90775) Pyruvate-flavodoxin
oxidoreductase (EC 1.-.-.-). [Escherichia coli]
>gi|1742256|dbj|BAA14987| (D90776) Pyruvate-flavodoxin
oxidoreductase (EC 1.-.-.-). [Escherichia coli]
>gi|1787642 (AE000234) putative oxidoreductase, Fe-S
subunit [Escherichia coli]
Length = 1174
Score = 62.5 bits (149), Expect = 6e-09
Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 19/315 (6%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYY-------RAEEEY 75
I G+ A A R + +AI YPITP S TM D +A +K+ + + E
Sbjct: 4 IDGNGAVASVAFRTSEVIAI-YPITPSS-TMAEQADAWAGNGLKNVWGDTPRVVEMQSEA 61
Query: 76 GAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLSIQP 134
GA++ S GLL + + G P VL V R V LSI
Sbjct: 62 GAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFG 121
Query: 135 DNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYV 194
D+ ++ + +G +L A N Q+ DF L + + K V P + +GF +H +
Sbjct: 122 DHSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSRV--PFIHFFDGFRTSHEINKI 179
Query: 195 ELPPED--MKLPPR---DPYKA-PVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQE 248
+D + L P+ D ++A + P I D Q + +AV+
Sbjct: 180 VPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDHV 239
Query: 249 VWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKV 308
+ N +A + Y +P AE ++ G A E G VG++KV
Sbjct: 240 EQAMNDFSAATGRQY-QPFEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLKV 298
Query: 309 KSLRPFPVDEIREAL 323
+ RPF + +AL
Sbjct: 299 RLYRPFSAKHLLQAL 313
emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1181
Score = 59.3 bits (141), Expect = 5e-08
Identities = 78/335 (23%), Positives = 131/335 (38%), Gaps = 32/335 (9%)
Query: 18 REKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDY------YRA 71
R K+ + G+ A A V A DVA YPITP S V A G +
Sbjct: 3 RAKQSMDGNTAAAH-VAYAYTDVAGIYPITPSSPMADSVDMWSAAGQENIFGNQVKVVEM 61
Query: 72 EEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTR-VVNAPL 130
+ E GA + GLL + + G +P+V V R V + L
Sbjct: 62 QSEAGAAGTVHGSLAAGALTTTFTASQGLLLMIPNMYKIAGEMLPSVFHVSARTVASHAL 121
Query: 131 SIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
+I D+ ++ G +L N Q+V D + + + ++ +P + +GF +H
Sbjct: 122 NIFGDHSDVYACRQVGFAMLAETNPQEVMDLSPVAHLAA--LEGKVPFINFFDGFRTSHE 179
Query: 191 KGYVE-LPPEDMK-LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQE 248
+E ED+K + D KA + + P + + + + ++
Sbjct: 180 IQKIEKWDYEDLKEMCNMDAVKA--------FRDHALNPEKPAMRGSHENGDVFFQHREA 231
Query: 249 VWSANRRAAKWIKHYLGGLIEVVNPDAEVF-----------VVASGCAAAQGREAQRYAT 297
+A ++ Y+ + E + D ++F ++A G E Y T
Sbjct: 232 CNTAYNNLPAIVEKYMAKVNEKLGTDYDLFNYYGAEDADRVIIAMGSICDVAEEVIDYLT 291
Query: 298 MEGLNVGLIKVKSLRPFPVDEIREAL-KNAKAVIV 331
+G VGL+KV+ RP+ + I +AL K AK V V
Sbjct: 292 AKGEKVGLVKVRLYRPWVSESILKALPKTAKKVAV 326
pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase
From Desulfovibrio Africanus >gi|4558092|pdb|1B0P|B
Chain B, Crystal Structure Of Pyruvate-Ferredoxin
Oxidoreductase From Desulfovibrio Africanus
>gi|4558221|pdb|2PDA|A Chain A, Crystal Structure Of The
Complex Between Pyruvate- Ferredoxin Oxidoreductase From
Desulfovibrio Africanus And Pyruvate.
>gi|4558222|pdb|2PDA|B Chain B, Crystal Structure Of The
Complex Between Pyruvate- Ferredoxin Oxidoreductase From
Desulfovibrio Africanus And Pyruvate.
Length = 1231
Score = 59.3 bits (141), Expect = 5e-08
Identities = 83/332 (25%), Positives = 126/332 (37%), Gaps = 31/332 (9%)
Query: 20 KKFITGSQAFAEA-VKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRA------E 72
KK +T A A V A +VA YPITP S D AQG + + +
Sbjct: 2 KKMMTTDGNTATAHVAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQ 61
Query: 73 EEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLS 131
E GA + GLL + + G +P V V R + A LS
Sbjct: 62 SEAGAAGAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALS 121
Query: 132 IQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAK 191
I D+ +I +G +L + + Q+ D L + + ++ +P + +GF +H
Sbjct: 122 IFGDHQDIYAARQTGFAMLASSSVQEAHDMALVAHLAA--IESNVPFMHFFDGFRTSHEI 179
Query: 192 GYVE-LPPEDM------------KLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238
+E L DM + +P V T + P Q
Sbjct: 180 QKIEVLDYADMASLVNQKALAEFRAKSMNPEHPHVRGT-AQNPDIYFQGREAANPYYLKV 238
Query: 239 YLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATM 298
I A + Q+V S R+ K + Y+G PDAE +V+ G + E +
Sbjct: 239 PGIVAEYMQKVASLTGRSYK-LFDYVGA------PDAERVIVSMGSSCETIEEVINHLAA 291
Query: 299 EGLNVGLIKVKSLRPFPVDEIREALKNAKAVI 330
+G +GLIKV+ RPF + AL + VI
Sbjct: 292 KGEKIGLIKVRLYRPFVSEAFFAALPASAKVI 323
emb|CAA70873| (Y09702) pyruvate-ferredoxin oxidoreductase [Desulfovibrio
africanus]
Length = 1232
Score = 59.3 bits (141), Expect = 5e-08
Identities = 83/332 (25%), Positives = 126/332 (37%), Gaps = 31/332 (9%)
Query: 20 KKFITGSQAFAEA-VKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRA------E 72
KK +T A A V A +VA YPITP S D AQG + + +
Sbjct: 3 KKMMTTDGNTATAHVAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQ 62
Query: 73 EEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLS 131
E GA + GLL + + G +P V V R + A LS
Sbjct: 63 SEAGAAGAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALS 122
Query: 132 IQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAK 191
I D+ +I +G +L + + Q+ D L + + ++ +P + +GF +H
Sbjct: 123 IFGDHQDIYAARQTGFAMLASSSVQEAHDMALVAHLAA--IESNVPFMHFFDGFRTSHEI 180
Query: 192 GYVE-LPPEDM------------KLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMS 238
+E L DM + +P V T + P Q
Sbjct: 181 QKIEVLDYADMASLVNQKALAEFRAKSMNPEHPHVRGT-AQNPDIYFQGREAANPYYLKV 239
Query: 239 YLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATM 298
I A + Q+V S R+ K + Y+G PDAE +V+ G + E +
Sbjct: 240 PGIVAEYMQKVASLTGRSYK-LFDYVGA------PDAERVIVSMGSSCETIEEVINHLAA 292
Query: 299 EGLNVGLIKVKSLRPFPVDEIREALKNAKAVI 330
+G +GLIKV+ RPF + AL + VI
Sbjct: 293 KGEKIGLIKVRLYRPFVSEAFFAALPASAKVI 324
gb|AAD35959.1|AE001753_15 (AE001753) pyruvate:ferredoxin 2-oxidoreductase-related protein
[Thermotoga maritima]
Length = 386
Score = 58.6 bits (139), Expect = 9e-08
Identities = 85/379 (22%), Positives = 154/379 (40%), Gaps = 33/379 (8%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVG-DLYAQGYVKDYYRAEEEYGA 77
E F+ G++A A +A YPITP +E ++ +L G V + + E+E +
Sbjct: 5 EMMFLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELPKVGGV--FVQMEDEIAS 62
Query: 78 MSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRV-VNAPLSIQPDN 136
+ SGPG E I P V + R+ + L +P
Sbjct: 63 AAAVVGASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPAQ 122
Query: 137 VEISYLL-----NSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAK 191
+I + ++ L+ + +V+ + + F ++E+ PVV + +
Sbjct: 123 GDIMQTRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRT--PVVFLMDAMLGHMRE 180
Query: 192 GYVELPPEDMKLPPRDPYKAP--------VPPTDCEIPPARIQRDAPVQKSNF-MSYLIH 242
+ PP+D +L + K VP ++ E A + K+ F +S L+H
Sbjct: 181 SFY--PPKDEELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVH 238
Query: 243 AVWQQEVWSAN------RRAAKWIKHYLGGLI---EVVNPDAEVFVVASGCAAAQGREAQ 293
+ S + RR I+ + + E DAE+ VVA G A +A
Sbjct: 239 DESGFPLSSPDAAEKLIRRLTNKIRLHADEIAFYEEYETEDAEILVVAYGIVARSAMKAV 298
Query: 294 RYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIP-NSG 352
+ A + + VGL K ++ P PV R+ + +++ E N+ G AKE+ ++I S
Sbjct: 299 KIARRDRIKVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMNL-GQYAKELISSIDRRSK 357
Query: 353 IVVDGPRVYGGMTLPVELI 371
++ +V G + P E++
Sbjct: 358 VIRTINKVNGELIKPEEIL 376
sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE
>gi|1006618|dbj|BAA10774| (D64005) pyruvate
oxidoreductase [Synechocystis sp.]
Length = 1199
Score = 58.6 bits (139), Expect = 9e-08
Identities = 91/369 (24%), Positives = 145/369 (38%), Gaps = 44/369 (11%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ-------GYVKDYYRAEEEY 75
+ G++A A + +AI YPITP S M D +A G V + E
Sbjct: 9 LDGNEAVARVAYLLSEVIAI-YPITPSSP-MGEWSDAWAAEHRPNLWGTVPLVVEMQSEG 66
Query: 76 GAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAP-LSIQP 134
GA + GL+ L + G VL V R + A LSI
Sbjct: 67 GAAGTVHGALQSGALTTTFTASQGLMLMLPNMHKIAGELTAMVLHVAARSLAAQGLSIFG 126
Query: 135 DNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYV 194
D+ ++ N+G +L + + Q+ DF L S +P + +GF +H + +
Sbjct: 127 DHSDVMAARNTGFAMLSSNSVQEAHDFALIATATS--FATRIPGLHFFDGFRTSHEEQKI 184
Query: 195 ELPPEDM---------KLPPRDPYKAPVPPT---DCEIPPARIQRDAPVQKSNFMSY--L 240
EL P+++ L R P P + P Q V + SY +
Sbjct: 185 ELLPQEVLRGLIKDEDVLAHRGRALTPDRPKLRGTAQNPDVYFQARETVNPF-YASYPNV 243
Query: 241 IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG 300
+ V +Q R + Y G +P+AE +V G A +E + T +G
Sbjct: 244 LEQVMEQFGQLTGRHYRPY--EYCG------HPEAERVIVLMGSGAETAQETVDFLTAQG 295
Query: 301 LNVGLIKVKSLRPFPVDEIREAL-KNAKAVIVPEH-----NIVGWLAKEVKAAIPNSGIV 354
VGL+KV+ RPF D + AL K + + V + +I L ++V A +G++
Sbjct: 296 EKVGLLKVRLYRPFAGDRLVNALPKTVQKIAVLDRCKEPGSIGEPLYQDVLTAFFEAGMM 355
Query: 355 VDGPRVYGG 363
P++ GG
Sbjct: 356 ---PKIIGG 361
gi|1888325 (U30149) pyruvate:ferredoxin oxidoreductase [Entamoeba histolytica]
Length = 1162
Score = 57.8 bits (137), Expect = 2e-07
Identities = 77/322 (23%), Positives = 120/322 (36%), Gaps = 29/322 (9%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ-------GYVKDYYRAEEEY 75
+ G+QA A V A DV+ +PITP S M D+++ G V D Y E E
Sbjct: 4 VDGNQA-AAYVSYALSDVSFIFPITPSSP-MAENADVWSSQGRKNVFGQVVDVYEMESEA 61
Query: 76 GAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVV-NAPLSIQP 134
GA GL+ + ++ G +P V V R + LSI
Sbjct: 62 GASGAVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAGQALSIFG 121
Query: 135 DNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYV 194
D+ ++ ++G +L + N Q D + + + ++ LP + +GF +H +
Sbjct: 122 DHSDVMACRSTGFCLLSSHNVQQCHDLAIVAHLAT--LEASLPFMHFFDGFRTSHEIQKI 179
Query: 195 -ELPPE------DMKLPPRDPYKA--PVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVW 245
+L + DMK R + P+ P+ V+KSN + +
Sbjct: 180 HQLTYDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVFFQAVEKSNADYLKVPEIV 239
Query: 246 QQEVWSANRRAAKWIK--HYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNV 303
Q+ + + K Y G DAE VV G A E Y G V
Sbjct: 240 QKYMDKVGELTGRHYKIFEYYGAA------DAERVVVVMGAAVPVLEECVDYLMKSGEKV 293
Query: 304 GLIKVKSLRPFPVDEIREALKN 325
G++ V RP+ E L N
Sbjct: 294 GVLSVHLYRPWSAKHFLEQLPN 315
gi|960283 (L27221) pyruvate:ferredoxin oxidoreductase [Giardia lamblia]
Length = 1253
Score = 57.8 bits (137), Expect = 2e-07
Identities = 93/412 (22%), Positives = 156/412 (37%), Gaps = 69/412 (16%)
Query: 18 REKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGY------VKDYYRA 71
+E+ I G+ A + V R +D +PITP S ++ AQG V +A
Sbjct: 8 QEQLCIDGATATSMMVYRL-IDFTAIFPITPSSVMAEMIEQYAAQGKKNIFGNVVTVRQA 66
Query: 72 EEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVN-APL 130
E GA+ S G+L + + G RIP VL V TR V A
Sbjct: 67 WSELGAIGTCHGAATAGALTATFSSSQGVLLMISNLYHMAGERIPFVLHVATRTVGMAAT 126
Query: 131 SIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
S+ D+ ++ + + + L + N Q+ +D +L + +V EG+ V+H
Sbjct: 127 SLATDHTDVYAIEGTNMCALSSCNVQECYDMSLVAHTTA--TNVQAAFCHFFEGYRVSHQ 184
Query: 191 KGYVELPPEDMKLPPRDPYKAPVPPTDCEIPPAR------IQRDAPVQKSNFMSYLIH-- 242
+++ +D A + E A+ + D P+ + + IH
Sbjct: 185 FETIQVFKDD----------ADIKDFLSEDQLAKWRSENAMDTDRPIASNIGLGGEIHMQ 234
Query: 243 ------AVWQ------QEVWSANRRAAKWIKH---YLGGLIEVVNPDAEVFVVASGCAAA 287
AV+ +E + R H Y G +P +V VV G +
Sbjct: 235 IVESQGAVFDSIPYRIEEAFDLLHRKTGRRYHCFEYFG------HPTPDVVVVVMGATSL 288
Query: 288 QGRE-AQRYATMEGLNVGLIKVKSLRPFPVDEIREAL-KNAKAVIVPEH-----NIVGWL 340
E VG ++V+ RPF ++ A+ K+AK V+ + N G L
Sbjct: 289 TFENVVDALVNRENRRVGFVRVRLFRPFSIELFSNAIPKSAKVVVALDRAPELLNAGGTL 348
Query: 341 AKEVKAAIPNSG----------IVVDGPRVYGGMTL-PVELIMEEIYKAFGI 381
+E AA+ +G +V G Y G L P +++ +Y+ F +
Sbjct: 349 YRETLAALMKTGRLGAGKNSVRLVAGGRYSYYGWELGPADVV--TLYETFDV 398
gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin oxidoreductase 2 [Giardia
intestinalis]
Length = 512
Score = 57.4 bits (136), Expect = 2e-07
Identities = 61/240 (25%), Positives = 97/240 (40%), Gaps = 26/240 (10%)
Query: 99 GLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLSIQPDNVEISYLLNSGLVVLHAENQQD 157
GLL + + G +PAV V R + LS+ D+ +I + +G ++ +E+ Q+
Sbjct: 29 GLLLMIPNMYKMAGEHLPAVFHVAARTIATHSLSVHGDHADIMAVRQTGCTIMVSEDIQE 88
Query: 158 VFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLPPRDPYKAPVPPTD 217
D +A + + + PVV A +GF +H VEL + L P PY
Sbjct: 89 AMDMAIAAHLTA--IYSSYPVVHAFDGFRTSHTIKKVELIDYE-HLRPHVPYD------- 138
Query: 218 CEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANR----------RAAKWIKHYLGGL 267
EI R + +P S +W Q + N+ RA + ++ G
Sbjct: 139 -EIEAFRQKSLSPQHPEMRGSCQGPPIWMQAGEADNKHYAEIPGHVERAFEKVREITGRS 197
Query: 268 IEVVN----PDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREAL 323
+ N PDA V+ G E Y G VG++ V RPF D++ EA+
Sbjct: 198 YKFFNYFGAPDATAVVIIMGSGYLTVHEVVEYLVERGDKVGVVCVHLFRPFCGDKLLEAI 257
gb|AAD36824.1|AE001814_6 (AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative
[Thermotoga maritima]
Length = 356
Score = 55.8 bits (132), Expect = 6e-07
Identities = 77/363 (21%), Positives = 138/363 (37%), Gaps = 31/363 (8%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETM-HLVGDLYAQGYVKDYYRAEEEYGA 77
+K + G++A AE+ RA + AYPITPQSE ++ L G V + + E E
Sbjct: 5 KKLMMKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLPEVGGV--FLQTESEIAT 62
Query: 78 MSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNV 137
++ S PG E I G +P V + R +IQP
Sbjct: 63 VNMVYGAACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGNIQPSQG 122
Query: 138 EISYLLNSG------LVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAK 191
+ + G L+VL Q+ D T F ++++ PV++ +G
Sbjct: 123 DYFQAVKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRN--PVLILADGM------ 174
Query: 192 GYVELPPEDMKLPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAV---WQQE 248
+ E ++LP +D + AR + + N + + Q++
Sbjct: 175 --IGQMMEPVELPEMRDLSTLPDHSDWALRGARNREPHRIAAFNIDPVGLEKMNKRLQEK 232
Query: 249 VWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKV 308
+W ++ + G AE +V G + EG+ GL +
Sbjct: 233 YRLIEASEQRWEEYRVDG--------AEYLMVGYGTMGRILKSVVDSLREEGIPAGLFRP 284
Query: 309 KSLRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRVYGGMTLPV 368
+L PFP ++E K + + V E + G + ++V+ ++ V R+ G + P
Sbjct: 285 VTLWPFPKRRLKELAKKVQLIFVVEMS-SGQMVEDVQISVEGKVPVHFYGRMGGVVPTPE 343
Query: 369 ELI 371
E++
Sbjct: 344 EIL 346
gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1098
Score = 55.0 bits (130), Expect = 1e-06
Identities = 79/332 (23%), Positives = 128/332 (37%), Gaps = 32/332 (9%)
Query: 21 KFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRA------EEE 74
K + G++A A A A +VA YPITP + V + A + +A + E
Sbjct: 4 KTMDGNEAAAYA-SYAFTEVAAIYPITPSTPMAESVDEWSAHDKKNVFDQAVNVVEMQSE 62
Query: 75 YGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNA-PLSIQ 133
GA + GLL + + G ++P V V R + LSI
Sbjct: 63 AGAAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALSIF 122
Query: 134 PDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
D+ ++ +G +L + + Q+ D + + K V P + +GF +H
Sbjct: 123 GDHQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKV--PFLHFFDGFRTSHEIQK 180
Query: 194 VE-LPPEDMK-LPPRDPYKA----------PVPPTDCEIPPARIQ-RDAPVQKSNFMSYL 240
+E + ED++ L D KA PV E P Q R+A + N + L
Sbjct: 181 IEVIDYEDLRPLVDIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPEL 240
Query: 241 IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG 300
+ + E+ R +Y DAE ++A G + E Y +G
Sbjct: 241 VEN-YMGEISKITGREYHLFNYYGA-------EDAERIIIAMGSISDAIEETIDYLNAKG 292
Query: 301 LNVGLIKVKSLRPFPVDEIREAL-KNAKAVIV 331
VG++KV RPF V+ + + K K + V
Sbjct: 293 EKVGVLKVHLFRPFSVEHFFKYIPKTVKKIAV 324
emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1175
Score = 54.3 bits (128), Expect = 2e-06
Identities = 79/332 (23%), Positives = 126/332 (37%), Gaps = 32/332 (9%)
Query: 21 KFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRA------EEE 74
K + G+ A A + A DV YPITP S V + QG + + + E
Sbjct: 5 KTMDGNTAAAH-IAYAFTDVTAIYPITPSSPMAEHVDEWAVQGRKNLFGQTVKVMEMQSE 63
Query: 75 YGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVV-NAPLSIQ 133
GA + GLL + + G +P V V R + L+I
Sbjct: 64 AGAAGAVHGSLQAGALTTTFTASQGLLLMIPNMYKIAGELLPGVFHVSARALATKSLNIF 123
Query: 134 PDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGY 193
D+ ++ +G +L + Q+V D + + + K V P + +GF +H
Sbjct: 124 GDHQDVMAARQTGFALLAEGSVQEVMDLSAVAHLAAIKGKV--PFLNFFDGFRTSHEIQK 181
Query: 194 VE-LPPEDMK-LPPRDPYKA----------PVPPTDCEIPPARIQ-RDAPVQKSNFMSYL 240
+E + ED++ L D KA PV E P Q R+A + N + L
Sbjct: 182 IEVIDYEDLRPLVDIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPEL 241
Query: 241 IHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEG 300
+ + E+ R +Y DAE ++A G + E Y +G
Sbjct: 242 VEN-YMGEISKITGREYHLFNYYGA-------EDAERIIIAMGSISDAIEETIDYLNAKG 293
Query: 301 LNVGLIKVKSLRPFPVDEIREAL-KNAKAVIV 331
VG++KV RPF V+ + + K K + V
Sbjct: 294 EKVGVLKVHLFRPFSVEHFFKYIPKTVKKIAV 325
sp|O27880|IORA_METTH INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2622988
(AE000938) indolepyruvate oxidoreductase, alpha subunit
[Methanobacterium thermoautotrophicum]
Length = 618
Score = 53.9 bits (127), Expect = 2e-06
Identities = 93/359 (25%), Positives = 151/359 (41%), Gaps = 49/359 (13%)
Query: 19 EKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVKDYYRAEEEYGAM 78
+K F+ G++A A + V VA YP TP SE +++ + + + + E+ A+
Sbjct: 13 DKLFLLGNEATVRAAIESGVGVASTYPGTPSSEIGNVLSGIAKRAGMYFEFSVNEKV-AL 71
Query: 79 SXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
GL ++ +S + A + V+T + S Q +
Sbjct: 72 EVAAAAAASGVRSFTFMKHVGLNVASDSFMSTAYTGVRAGMVVLTADDPSMFSSQNEQDN 131
Query: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
Y + L +L + Q+V +F F +SE D LPV++ T V+H +G VE+
Sbjct: 132 RHYARLACLPLLEPSDPQEVLEFMNHAFELSE--DYGLPVLLRTT-TRVSHMRGVVEVGS 188
Query: 199 EDMKLPP-----RDPYK-APVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSA 252
M+ P +DP + PVP T AR+ V K M L + E+
Sbjct: 189 R-MREPSEGFFRKDPERFVPVPAT------ARVMHRKLVDK---MKELRIRADESEL--- 235
Query: 253 NRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATME--GLNVGLIKVKS 310
NR + GG D+E+ VVASG G Y +E GL + ++K+
Sbjct: 236 NR-------VFNGG------SDSELGVVASG-----GAFNYVYDALESLGLELPVLKLGF 277
Query: 311 LRPFPVDEIREALKNAKAVIVPEHNIVGWLAKEVKAAIPNSGIVVDGPRVYGGM--TLP 367
PFP + E L K V+V E + + +EV A ++ + +D V+G + TLP
Sbjct: 278 TYPFPAGLVEEFLSGLKRVLVVE-EVDPIMEREVLAVAGSARLDLD---VHGKLDGTLP 332
emb|CAA16032| (AL021246) hypothetical protein Rv2455c [Mycobacterium
tuberculosis]
Length = 653
Score = 53.1 bits (125), Expect = 4e-06
Identities = 81/364 (22%), Positives = 144/364 (39%), Gaps = 52/364 (14%)
Query: 17 PREKKFITGSQAFAEAV----KRANVDVAI-AYPITPQSETMHLVGDLYAQGYVKDYYRA 71
P E + I+G+ A A + + A + V + +YPITP S+ +H + + + ++A
Sbjct: 248 PGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHELSK--HKNFNVVTFQA 305
Query: 72 EEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLS 131
E+E G + SGPG+ EA+ LGVMT + +
Sbjct: 306 EDEIGGICAALGAAYGGALGVTSTSGPGISLKSEAL----------GLGVMTELPLLVID 355
Query: 132 IQ--------PDNVEISYLL--------NSGLVVLHAENQQDVFDFTLAGFVISEKVDVY 175
+Q P E + LL S + VL + D F+ L I+ V +
Sbjct: 356 VQRGGPSTGLPTKTEQADLLQALYGRNGESPVAVLAPRSPADCFETALEAVRIA--VSYH 413
Query: 176 LPVVVATEGFFVTHAKGYVELPPEDMKLPPRDPYKAPVPP------------TDCEIP-- 221
PV++ ++G ++ + +P + P + + P P IP
Sbjct: 414 TPVILLSDGAIANGSEPW-RIPDVNALPPIKHTFAKPGEPFQPYARDRETLARQFAIPGT 472
Query: 222 PARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVA 281
P R ++ +N + + ++ R+A H ++ DAE+ ++
Sbjct: 473 PGLEHRIGGLEAANGSGDISYEPTNHDLMVRLRQAKIDGIHVPDLEVDDPTGDAELLLIG 532
Query: 282 SGCAAAQGREAQRYATMEGLNVGLIKVKSLRPFPVDEIREALKNAKAVIVPEHNIVGWLA 341
G + EA R A G V ++ L PFP + + E L+ V+ PE N+ G LA
Sbjct: 533 WGSSYGPIGEACRRARRRGTKVAHAHLRYLNPFPAN-LGEVLRRYPKVVAPELNL-GQLA 590
Query: 342 KEVK 345
+ ++
Sbjct: 591 QVLR 594
sp|O28783|IORA_ARCFU INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORA (IOR) (INDOLEPYRUVATE
FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2649079
(AE001000) indolepyruvate ferredoxin oxidoreductase,
subunit alpha (iorA) [Archaeoglobus fulgidus]
Length = 623
Score = 49.2 bits (115), Expect = 6e-05
Identities = 79/328 (24%), Positives = 132/328 (40%), Gaps = 42/328 (12%)
Query: 15 EAPREKKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDL--YAQGYVKDY--YR 70
+A EK F+ G++A A A +DV AYP TP SE + D +G + Y Y
Sbjct: 8 DAEGEKVFLLGNEAIARGAIEAGIDVFAAYPGTPSSEIADTLSDACRLLRGKMDFYMEYS 67
Query: 71 AEEEYGAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPL 130
A E+ A G+ + + S+ ++T +
Sbjct: 68 ANEKV-AFEVAVGASLAGKRAMATMKHVGVNVAADPLFSFAYVGARGGFVLVTADDPSMH 126
Query: 131 SIQPDNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHA 190
S Q + Y + L V+ + Q+ D+ F +SEK LP+++ + ++HA
Sbjct: 127 SSQNEQDNRWYGKAAKLPVVEPSSVQEAKDYAKLCFDLSEKFG--LPMILRSY-TRLSHA 183
Query: 191 KGYVELPPEDMKLPPRDPYKAP---VPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQ 247
G VEL K+P ++ + P TD + PA ++ P+ L+ + +
Sbjct: 184 SGVVELG----KIPEKEFSRVEWERHPETDV-VLPAHARKLKPI--------LLEKLEKI 230
Query: 248 EVWSANRRAAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGL-- 305
E + N W+ D +V ++A G + A +EA +E LN+ L
Sbjct: 231 ERY-FNSSEMNWVD----------EGDGDVGIIACGLSYAYTKEA-----LENLNLNLPV 274
Query: 306 IKVKSLRPFPVDEIREALKNAKAVIVPE 333
+K+ S+ P P I + K VIV E
Sbjct: 275 LKLSSMHPLPERLIENFVSQMKKVIVVE 302
pir||S58236 pyruvate oxidoreductase - Entamoeba histolytica
>gi|929587|emb|CAA90575| (Z50193) pyruvate
oxidoreductase [Entamoeba histolytica]
Length = 1165
Score = 49.2 bits (115), Expect = 6e-05
Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 12/175 (6%)
Query: 23 ITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQ-------GYVKDYYRAEEEY 75
+ G+QA A V A DV+ +PITP S M D+++ G V D Y E E
Sbjct: 4 VDGNQA-AAYVSYALSDVSFIFPITPSSP-MAENADVWSSQGRKNVFGQVVDVYEMESEA 61
Query: 76 GAMSXXXXXXXXXXXXXXXXSGPGLLRGLEAIVSWPGHRIPAVLGVMTR-VVNAPLSIQP 134
GA GL+ + ++ G +P V V R + LSI
Sbjct: 62 GASGAVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAEQALSIFG 121
Query: 135 DNVEISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTH 189
D+ ++ ++G +L + N Q D + + + ++ LP + +GF +H
Sbjct: 122 DHSDVMACRSTGFCLLSSHNVQQCHDLAIVAHLAT--LEASLPFMHFFDGFRTSH 174
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Jan 12, 2000 2:26 PM
Number of letters in database: 136,724,657
Number of sequences in database: 444,417
Lambda K H
0.319 0.137 0.405
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105490408
Number of Sequences: 444417
Number of extensions: 4368669
Number of successful extensions: 13004
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 12796
Number of HSP's gapped (non-prelim): 173
length of query: 389
length of database: 136,724,657
effective HSP length: 55
effective length of query: 334
effective length of database: 112,281,722
effective search space: 37502095148
effective search space used: 37502095148
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 71 (32.1 bits)
