Detailed annotation info for ACL00001313;
Annotation NameDihydrolipoyl dehydrogenase, mitochondrial precursor related cluster
Score712&emsp
E-value3e-74
% Sequence Identity67% (130/194)
LocusDLDH
EC Number1.8.1.4
COG Function Energy production and conversion
KEGG Pathway
SourceAccessionDescriptionScoreE-value% Sequence IdentityLocusEC NumberInformative HitFunction/PathwayGeneOntology
SSUNo hits found0
LSUNo hits found0
uniref90UniRef90_P09624Dihydrolipoyl dehydrogenase, mitochondrial precursor related cluster7123e-7467% (130/194)DLDH1.8.1.41GO:0004148|dihydrolipoyl dehydrogenase activity|IDA; GO:0004148|dihydrolipoyl dehydrogenase activity|IEA; GO:0005737|cytoplasm|IEA; GO:0005739|mitochondrion|IEA; GO:0006118|electron transport|IEA; GO:0006546|glycine catabolism|IMP; GO:0006550|isoleucine catabolism|IMP; GO:0006552|leucine catabolism|IMP; GO:0006564|L-serine biosynthesis|IMP; GO:0006574|valine catabolism|IMP; GO:0009353|oxoglutarate dehydrogenase complex (sensu Eukaryota)|IDA; GO:0015036|disulfide oxidoreductase activity|IEA; GO:0016491|oxidoreductase activity|IEA; GO:0042645|mitochondrial nucleoid|IDA; GO:0050660|FAD binding|IEA
nr1JEHChain A, Crystal Structure Of Yeast E3, Lipoamide Dehydrogenase pdb|1JEH|B Chain B, Crystal Structure Of Yeast E3, Lipoamide Dehydrogenase7127e-7467% (130/194)1
cogYFL018c[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes7127e-7567% (130/194)1 Energy production and conversion
keggsce:YFL018CLPD1; an FAD flavoprotein which contains a pair of redox-active cysteines involved in the transfer of reducing equivalents from the FAD cofactor to the substrate [EC:1.8.1.4] [KO:K00382]7123e-7467% (130/194)LPD11.8.1.41 Citrate cycle (TCA cycle) Glycine, serine and threonine metabolism Glycolysis / Gluconeogenesis Pyruvate metabolism
smartNo hits found0
pfamPF02852pfam02852, Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain4021e-3956% (62/110)Pyr_redox_dim1
pfam2PF00070pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase1547e-1147% (25/53)Pyr_redox2
est_othersBJ596439BJ596439 normalized full length cDNA library, chloronemata, caulonemata and rhizoid-like protonemata Physcomitrella patens subsp. patens cDNA clone pphn16g10 3'.2252e-3449% (54/109)1